|
2020-10-05 |
2020-10-01 |
S
Sale
|
Large shareholder
|
66,518
+5.4%
262.75
US$401,924
|
66,518
+5.4%
|
262.75
|
US$401,924
|
|
|
2020-03-18 |
2020-03-16 |
B
Purchase
|
Large shareholder
|
81,548
+26.6%
21.99
US$3,949,517
|
81,548
+26.6%
|
21.99
|
US$3,949,517
|
|
|
2020-02-27 |
2020-02-25 |
B
Purchase
|
Large shareholder
|
70,759
-45.9%
277.44
US$2,684,418
|
70,759
-45.9%
|
277.44
|
US$2,684,418
|
|
|
2020-02-27 |
2020-02-25 |
B
Purchase
|
Large shareholder
|
24,000
+8.3%
8.29
US$198,960
|
24,000
+8.3%
|
8.29
|
US$198,960
|
|
|
2020-01-28 |
2020-01-27 |
B
Purchase
|
Large shareholder
|
8,000
+2.9%
9.41
US$75,280
|
8,000
+2.9%
|
9.41
|
US$75,280
|
|
|
2020-01-28 |
2020-01-27 |
B
Purchase
|
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2020-01-28 |
2020-01-27 |
B
Purchase
|
Large shareholder
|
8,000
+0.2%
9.43
US$75,440
|
8,000
+0.2%
|
9.43
|
US$75,440
|
|
|
2020-01-28 |
2020-01-24 |
B
Purchase
|
Large shareholder
|
40,000
+16.7%
9.72
US$388,800
|
40,000
+16.7%
|
9.72
|
US$388,800
|
|
|
2020-01-28 |
2020-01-24 |
B
Purchase
|
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2020-01-28 |
2020-01-24 |
B
Purchase
|
Large shareholder
|
34,000
+0.8%
9.58
US$325,720
|
34,000
+0.8%
|
9.58
|
US$325,720
|
|
|
2020-01-13 |
2020-01-10 |
B
Purchase
|
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2020-01-13 |
2020-01-10 |
B
Purchase
|
Large shareholder
|
18,000
+0.4%
11.64
US$209,520
|
18,000
+0.4%
|
11.64
|
US$209,520
|
|
|
2020-01-13 |
2020-01-09 |
B
Purchase
|
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2020-01-13 |
2020-01-09 |
B
Purchase
|
Large shareholder
|
12,466
+0.3%
12.33
US$153,706
|
12,466
+0.3%
|
12.33
|
US$153,706
|
|
|
2020-01-13 |
2020-01-09 |
S
Sale
|
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2020-01-13 |
2020-01-09 |
S
Sale
|
Large shareholder
|
12,466
-0.3%
12.43
US$154,952
|
12,466
-0.3%
|
12.43
|
US$154,952
|
|
|
2019-08-09 |
2019-08-09 |
B
Purchase
|
Camber Capital Management LP
|
3,400
+0.1%
9.18
US$31,206
|
3,400
+0.1%
|
9.18
|
US$31,206
|
|
|
2019-08-09 |
2019-08-09 |
B
Purchase
|
Camber Capital Management LP
|
26,600
+0.6%
8.94
US$237,791
|
26,600
+0.6%
|
8.94
|
US$237,791
|
|
|
2019-08-09 |
2019-08-07 |
B
Purchase
|
ARMISTICE CAPITAL, LLC
Large shareholder
|
40,000
+20.0%
7.43
US$297,200
|
40,000
+20.0%
|
7.43
|
US$297,200
|
|
|
2019-08-09 |
2019-08-07 |
B
Purchase
|
ARMISTICE CAPITAL, LLC
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2019-08-09 |
2019-08-07 |
B
Purchase
|
ARMISTICE CAPITAL, LLC
Large shareholder
|
260,000
+6.8%
7.32
US$1,903,200
|
260,000
+6.8%
|
7.32
|
US$1,903,200
|
|
|
2019-08-09 |
2019-08-07 |
B
Purchase
|
Camber Capital Management LP
|
4,000
+0.1%
7.58
US$30,300
|
4,000
+0.1%
|
7.58
|
US$30,300
|
|
|
2019-08-09 |
2019-08-07 |
B
Purchase
|
Camber Capital Management LP
|
50,000
+1.2%
7.74
US$387,000
|
50,000
+1.2%
|
7.74
|
US$387,000
|
|
|
2019-08-09 |
2019-08-07 |
B
Purchase
|
Camber Capital Management LP
|
301,000
+7.5%
7.79
US$2,343,496
|
301,000
+7.5%
|
7.79
|
US$2,343,496
|
|
|
2019-06-27 |
2019-06-27 |
B
Purchase
|
Large shareholder
|
20,000
+11.1%
9.47
US$189,400
|
20,000
+11.1%
|
9.47
|
US$189,400
|
|
|
2019-06-27 |
2019-06-27 |
B
Purchase
|
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2019-06-27 |
2019-06-27 |
B
Purchase
|
Large shareholder
|
44,000
+1.2%
9.52
US$418,880
|
44,000
+1.2%
|
9.52
|
US$418,880
|
|
|
2019-06-27 |
2019-06-26 |
B
Purchase
|
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2019-06-27 |
2019-06-26 |
B
Purchase
|
Large shareholder
|
120,000
+3.3%
9.13
US$1,095,600
|
120,000
+3.3%
|
9.13
|
US$1,095,600
|
|
|
2019-06-27 |
2019-06-25 |
B
Purchase
|
Large shareholder
|
30,000
+20.0%
8.86
US$265,800
|
30,000
+20.0%
|
8.86
|
US$265,800
|
|
|
2019-06-27 |
2019-06-25 |
B
Purchase
|
Large shareholder
|
25,000
+20.0%
8.85
US$221,250
|
25,000
+20.0%
|
8.85
|
US$221,250
|
|
|
2019-06-27 |
2019-06-25 |
B
Purchase
|
Large shareholder
|
0
0.00
US$0
|
0
|
0.00
|
US$0
|
|
|
2019-06-27 |
2019-06-25 |
B
Purchase
|
Large shareholder
|
259,016
+7.7%
8.59
US$2,224,947
|
259,016
+7.7%
|
8.59
|
US$2,224,947
|
|
|
2019-05-29 |
2019-05-28 |
B
Purchase
|
Chief Medical Officer
|
10,000
+14.0%
9.91
US$99,100
|
10,000
+14.0%
|
9.91
|
US$99,100
|
|
|
2019-05-09 |
2019-05-09 |
B
Purchase
|
Chief Human Resources Officer
|
5,000
+7.2%
10.93
US$54,650
|
5,000
+7.2%
|
10.93
|
US$54,650
|
|
|
2019-05-09 |
2019-05-09 |
B
Purchase
|
President & CEO
Executive Director
|
10,000
+2.1%
10.70
US$107,000
|
10,000
+2.1%
|
10.70
|
US$107,000
|
|
|
2019-03-11 |
2019-03-07 |
PlS
Planned sale
|
EVP, General Counsel
|
1,425
-1.8%
14.01
US$19,964
|
1,425
-1.8%
|
14.01
|
US$19,964
|
|
|
2018-08-08 |
2018-08-07 |
PlS
Planned sale
|
HEIDEN WILLIAM K
President & CEO
Executive Director
|
5,000
-1.5%
25.00
US$125,000
|
5,000
-1.5%
|
25.00
|
US$125,000
|
|
|
2018-06-05 |
2018-06-04 |
PlS
Planned sale
|
HEIDEN WILLIAM K
President & CEO
Executive Director
|
20,000
-5.7%
25.00
US$500,000
|
20,000
-5.7%
|
25.00
|
US$500,000
|
|
|
2018-03-06 |
2018-03-06 |
PlS
Planned sale
|
Vittiglio Joseph
EVP, General Counsel
|
770
-1.4%
20.80
US$16,016
|
770
-1.4%
|
20.80
|
US$16,016
|
|
|
2017-08-30 |
2017-08-29 |
PlS
Planned sale
|
Vittiglio Joseph
SVP, General Counsel
|
1,250
-3.6%
16.75
US$20,938
|
1,250
-3.6%
|
16.75
|
US$20,938
|
|
|
2017-07-14 |
2017-07-13 |
PlS
Planned sale
|
Krop Julie
SVP Clinical & Regulatory, CMO
Officer
|
4,938
-14.8%
20.00
US$98,760
|
4,938
-14.8%
|
20.00
|
US$98,760
|
|
|
2017-05-02 |
2017-05-01 |
PlS
Planned sale
|
Krop Julie
SVP Clinical & Regulatory, CMO
Officer
|
1,891
-4.9%
24.45
US$46,235
|
1,891
-4.9%
|
24.45
|
US$46,235
|
|
|
2016-10-20 |
2016-10-20 |
PlS
Planned sale
|
Krop Julie
SVP Clinical & Regulatory, CMO
Officer
|
4,938
-17.3%
24.80
US$122,462
|
4,938
-17.3%
|
24.80
|
US$122,462
|
|
|
2015-11-10 |
2015-11-10 |
B
Purchase
|
Fallon John A.
Non-Executive Director
|
3,230
+113.1%
31.20
US$100,776
|
3,230
+113.1%
|
31.20
|
US$100,776
|
|
|
2015-08-07 |
2015-08-05 |
PlS
Planned sale
|
THOMAS FRANK E
President & COO
Officer
|
15,000
-12.1%
66.85
US$1,002,750
|
15,000
-12.1%
|
66.85
|
US$1,002,750
|
|
|
2015-07-17 |
2015-07-15 |
PlS
Planned sale
|
HEIDEN WILLIAM K
CEO
Executive Director
|
20,000
-8.8%
75.00
US$1,500,000
|
20,000
-8.8%
|
75.00
|
US$1,500,000
|
|
|
2015-06-17 |
2015-06-15 |
PlS
Planned sale
|
Holmes Scott A
SVP, Finance and Treasurer
Officer
|
6,234
-10.7%
66.63
US$415,371
|
6,234
-10.7%
|
66.63
|
US$415,371
|
|
|
2015-06-08 |
2015-06-05 |
PlS
Planned sale
|
HEIDEN WILLIAM K
CEO
Executive Director
|
12,128
-5.5%
71.52
US$867,395
|
12,128
-5.5%
|
71.52
|
US$867,395
|
|
|
2015-06-08 |
2015-06-05 |
PlS
Planned sale
|
HEIDEN WILLIAM K
CEO
Executive Director
|
4,680
-2.1%
70.69
US$330,829
|
4,680
-2.1%
|
70.69
|
US$330,829
|
|
|
2015-06-08 |
2015-06-05 |
PlS
Planned sale
|
HEIDEN WILLIAM K
CEO
Executive Director
|
36,550
-13.9%
69.77
US$2,550,094
|
36,550
-13.9%
|
69.77
|
US$2,550,094
|
|
|
2015-06-08 |
2015-06-05 |
PlS
Planned sale
|
HEIDEN WILLIAM K
CEO
Executive Director
|
6,642
-2.5%
68.90
US$457,634
|
6,642
-2.5%
|
68.90
|
US$457,634
|
|
|
2015-06-08 |
2015-06-04 |
S
Sale
|
THOMAS FRANK E
President & COO
Officer
|
7,996
-6.8%
69.76
US$557,801
|
7,996
-6.8%
|
69.76
|
US$557,801
|
|
|
2015-06-08 |
2015-06-04 |
S
Sale
|
THOMAS FRANK E
President & COO
Officer
|
12,004
-9.3%
69.27
US$831,517
|
12,004
-9.3%
|
69.27
|
US$831,517
|
|
|
2015-06-05 |
2015-06-03 |
S
Sale
|
Wilson Kenneth H
SVP, Sales and Marketing
Officer
|
5,388
-17.7%
68.77
US$370,533
|
5,388
-17.7%
|
68.77
|
US$370,533
|
|
|
2015-06-05 |
2015-06-03 |
S
Sale
|
Holmes Scott A
SVP, Finance and Treasurer
Officer
|
22,516
-42.2%
68.88
US$1,550,902
|
22,516
-42.2%
|
68.88
|
US$1,550,902
|
|
|
2015-01-09 |
2015-01-09 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
17,493
-0.7%
43.48
US$760,596
|
17,493
-0.7%
|
43.48
|
US$760,596
|
|
|
2015-01-09 |
2015-01-08 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
25,169
-1.0%
46.00
US$1,157,774
|
25,169
-1.0%
|
46.00
|
US$1,157,774
|
|
|
2015-01-09 |
2015-01-08 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
10,000
-0.4%
46.25
US$462,500
|
10,000
-0.4%
|
46.25
|
US$462,500
|
|
|
2015-01-09 |
2015-01-08 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
55,000
-2.1%
45.90
US$2,524,500
|
55,000
-2.1%
|
45.90
|
US$2,524,500
|
|
|
2015-01-09 |
2015-01-08 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
52,338
-1.9%
46.11
US$2,413,305
|
52,338
-1.9%
|
46.11
|
US$2,413,305
|
|
|
2015-01-09 |
2015-01-07 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
1,090,000
-28.7%
46.60
US$50,794,000
|
1,090,000
-28.7%
|
46.60
|
US$50,794,000
|
|
|
2014-02-26 |
2014-02-26 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
400
-1.6%
21.58
US$8,632
|
400
-1.6%
|
21.58
|
US$8,632
|
|
|
2014-01-09 |
2014-01-09 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
200
-0.8%
22.41
US$4,482
|
200
-0.8%
|
22.41
|
US$4,482
|
|
|
2014-01-09 |
2014-01-09 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
100
-0.4%
21.40
US$2,140
|
100
-0.4%
|
21.40
|
US$2,140
|
|
|
2014-01-09 |
2014-01-09 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
1,700
-6.3%
20.61
US$35,037
|
1,700
-6.3%
|
20.61
|
US$35,037
|
|
|
2014-01-07 |
2014-01-07 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
2,500
-8.0%
24.10
US$60,250
|
2,500
-8.0%
|
24.10
|
US$60,250
|
|
|
2013-02-26 |
2013-02-26 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
400
-100.0%
16.37
US$6,548
|
400
-100.0%
|
16.37
|
US$6,548
|
|
|
2013-02-26 |
2013-02-25 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
433
-52.0%
16.39
US$7,097
|
433
-52.0%
|
16.39
|
US$7,097
|
|
|
2013-01-09 |
2013-01-09 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
3,000
-100.0%
15.80
US$47,407
|
3,000
-100.0%
|
15.80
|
US$47,407
|
|
|
2013-01-09 |
2013-01-08 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
3,000
-50.0%
15.87
US$47,600
|
3,000
-50.0%
|
15.87
|
US$47,600
|
|
|
2013-01-07 |
2013-01-04 |
PlS
Planned sale
|
White Christopher G
Chief Business Officer
Officer
|
4,000
-40.0%
16.03
US$64,102
|
4,000
-40.0%
|
16.03
|
US$64,102
|
|
|
2013-01-04 |
2013-01-03 |
PlS
Planned sale
|
THOMAS FRANK E
EVP, COO
Officer
|
10,000
-31.2%
15.60
US$155,969
|
10,000
-31.2%
|
15.60
|
US$155,969
|
|
|
2012-12-06 |
2012-12-05 |
PlS
Planned sale
|
Holmes Scott A
Chief Accounting Officer
Officer
|
2,500
-100.0%
14.79
US$36,975
|
2,500
-100.0%
|
14.79
|
US$36,975
|
|
|
2012-09-13 |
2012-09-12 |
PlS
Planned sale
|
Holmes Scott A
Chief Accounting Officer
Officer
|
750
-100.0%
15.54
US$11,655
|
750
-100.0%
|
15.54
|
US$11,655
|
|