Prothena Corporation PLC (PRTA)

Prothena Corporation witnessed significant buying activity recently, primarily driven by William P. Scully, who acquired substantial shares following the latest earnings report. Conversely, several officers executed planned sales of their holdings. These transactions occurred amidst a five percent decline in stock value over the past quarter, reflecting mixed sentiment among key stakeholders regarding current market performance.
Ticker: PRTA Exchange: NSM


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Insider trades have triggered activity signals for Prothena Corporation PLC. Upgrade to see score, net flow, insiders and the full signal context.

Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
75.74
Quantity 97,531 -33.0%
Value US$4,827,866
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
332.31
Quantity 23,937 +8.7%
Value US$1,383,719
Kingston Anne Evans Chief Strategy Officer Officer
Transaction date
Planned sale
Price
140.18
Quantity 99,272 -2.8%
Value US$3,211,430
Isaacs Michael John General Counsel & Company Sec. Officer
Transaction date
Planned sale
Price
8.47
Quantity 1,000 -19.0%
Value US$100,000
ANNE KINGSTON Officer Officer
Transaction date
Proposed sale
Price
8.47
Quantity 1,000
Value US$100,000
MICHAEL JOHN ISAACS Officer Officer
Transaction date
Proposed sale
Price
8.47
Quantity 1,000
Value US$100,000
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
7.90
Quantity 20,000 +2.7%
Value US$157,990
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
8.17
Quantity 125,000 +13.4%
Value US$1,021,225
MALECEK MICHAEL J Previous Officer Officer
Transaction date
Proposed sale
Price
9.25
Quantity 80,000
Value US$740,000
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
9.31
Quantity 50,000 +5.6%
Value US$465,295
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
9.43
Quantity 50,000 +6.0%
Value US$471,300
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
9.81
Quantity 100,000 +13.6%
Value US$981,300
3.1
EcoR1 Capital, LLC Large shareholder
Transaction date
Sale
Price
7.64
Quantity 1,984,053 -27.2%
Value US$15,164,712
3.1
EcoR1 Capital, LLC Large shareholder
Transaction date
Sale
Price
8.11
Quantity 977,693 -11.8%
Value US$7,930,166
3.1
EcoR1 Capital, LLC Large shareholder
Transaction date
Sale
Price
8.36
Quantity 3,317,938 -28.6%
Value US$27,744,929
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
12.79
Quantity 100,000 +15.7%
Value US$1,279,040
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
12.99
Quantity 30,000 +4.8%
Value US$389,640
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
13.39
Quantity 800 +0.1%
Value US$10,715
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
13.37
Quantity 1,200 +0.2%
Value US$16,038
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
15.91
Quantity 2,000 +0.3%
Value US$31,813
1.8
SCULLY WILLIAM P Large shareholder
Transaction date
Purchase
Price
13.93
Quantity 73,436 +6.0%
Value US$1,022,670
Walker Karin L Officer Officer
Transaction date
Proposed sale
Price
34.00
Quantity 5,000
Value US$170,000
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
34.00
Quantity 5,000 -100.0%
Value US$170,000
Walker Karin L Officer Officer
Transaction date
Proposed sale
Price
37.29
Quantity 5,000
Value US$186,450
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
37.45
Quantity 3,322 -100.0%
Value US$124,409
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
36.68
Quantity 1,678 -33.6%
Value US$61,543
Walker Karin L Officer Officer
Transaction date
Proposed sale
Price
34.00
Quantity 5,000
Value US$170,000
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
34.00
Quantity 5,000 -100.0%
Value US$170,000
Walker Karin L Officer Officer
Transaction date
Proposed sale
Price
41.27
Quantity 5,000
Value US$206,350
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
42.28
Quantity 294 -100.0%
Value US$12,430
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
41.38
Quantity 2,917 -90.8%
Value US$120,718
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
40.27
Quantity 1,789 -35.8%
Value US$72,043
Smith Brandon S. Officer Officer
Transaction date
Proposed sale
Price
47.29
Quantity 4,000
Value US$189,160
Smith Brandon S. Chief Operating Officer Officer
Transaction date
Planned sale
Price
47.74
Quantity 444 -100.0%
Value US$21,198
Smith Brandon S. Chief Operating Officer Officer
Transaction date
Planned sale
Price
46.62
Quantity 3,556 -88.9%
Value US$165,786
Karp Carol D. Officer Officer
Transaction date
Proposed sale
Price
47.40
Quantity 5,000
Value US$237,000
Karp Carol D. Chief Regulatory Officer Officer
Transaction date
Planned sale
Price
47.29
Quantity 663 -100.0%
Value US$31,355
Karp Carol D. Chief Regulatory Officer Officer
Transaction date
Planned sale
Price
46.51
Quantity 4,337 -86.7%
Value US$201,729
Malecek Michael J Officer Officer
Transaction date
Proposed sale
Price
48.21
Quantity 5,000
Value US$241,050
Malecek Michael J Chief Legal Officer Officer
Transaction date
Planned sale
Price
48.31
Quantity 404 -100.0%
Value US$19,519
Malecek Michael J Chief Legal Officer Officer
Transaction date
Planned sale
Price
47.29
Quantity 4,596 -91.9%
Value US$217,366
2.5
Patel Sanjiv Director Non-Executive Director
Transaction date
Proposed sale
Price
50.00
Quantity 35,000
Value US$1,750,000
KARIN WALKER Officer Officer
Transaction date
Proposed sale
Price
52.36
Quantity 5,000
Value US$261,806
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
52.36
Quantity 5,000 -100.0%
Value US$261,807
Garren Hideki Officer Officer
Transaction date
Proposed sale
Price
55.39
Quantity 2,000
Value US$110,780
Smith Brandon S. Officer Officer
Transaction date
Proposed sale
Price
55.39
Quantity 4,000
Value US$221,560
Smith Brandon S. Chief Operating Officer Officer
Transaction date
Planned sale
Price
55.96
Quantity 114 -100.0%
Value US$6,379
Smith Brandon S. Chief Operating Officer Officer
Transaction date
Planned sale
Price
55.48
Quantity 3,886 -97.2%
Value US$215,584
Garren Hideki Chief Medical Officer Officer
Transaction date
Planned sale
Price
55.48
Quantity 2,000 -100.0%
Value US$110,952
Karp Carol D. Officer Officer
Transaction date
Proposed sale
Price
54.61
Quantity 5,000
Value US$273,050
Karp Carol D. Chief Regulatory Officer Officer
Transaction date
Planned sale
Price
55.27
Quantity 6 -100.0%
Value US$332
Karp Carol D. Chief Regulatory Officer Officer
Transaction date
Planned sale
Price
54.76
Quantity 4,994 -99.9%
Value US$273,472
Malecek Michael J Officer Officer
Transaction date
Proposed sale
Price
55.01
Quantity 5,000
Value US$275,066
Malecek Michael J Chief Legal Officer Officer
Transaction date
Planned sale
Price
56.21
Quantity 14 -100.0%
Value US$787
Malecek Michael J Chief Legal Officer Officer
Transaction date
Planned sale
Price
55.39
Quantity 2,664 -99.5%
Value US$147,551
Malecek Michael J Chief Legal Officer Officer
Transaction date
Planned sale
Price
54.58
Quantity 2,322 -46.4%
Value US$126,728
KARIN WALKER Officer Officer
Transaction date
Proposed sale
Price
57.18
Quantity 5,000
Value US$285,922
Walker Karin L Chief Accounting Officer Officer
Transaction date
Planned sale
Price
57.18
Quantity 5,000 -100.0%
Value US$285,922
Smith Brandon S. Officer Officer
Transaction date
Proposed sale
Price
58.71
Quantity 4,000
Value US$234,844
Garren Hideki Officer Officer
Transaction date
Proposed sale
Price
58.74
Quantity 2,000
Value US$117,480
Smith Brandon S. Chief Operating Officer Officer
Transaction date
Planned sale
Price
59.91
Quantity 401 -100.0%
Value US$24,025
Smith Brandon S. Chief Operating Officer Officer
Transaction date
Planned sale
Price
59.15
Quantity 1,373 -77.4%
Value US$81,217
Smith Brandon S. Chief Operating Officer Officer
Transaction date
Planned sale
Price
58.22
Quantity 2,226 -55.6%
Value US$129,602
Garren Hideki Chief Medical Officer Officer
Transaction date
Planned sale
Price
59.74
Quantity 374 -100.0%
Value US$22,341
Garren Hideki Chief Medical Officer Officer
Transaction date
Planned sale
Price
58.93
Quantity 748 -66.7%
Value US$44,079
Garren Hideki Chief Medical Officer Officer
Transaction date
Planned sale
Price
58.15
Quantity 878 -43.9%
Value US$51,059
Zago Wagner M. Officer Officer
Transaction date
Proposed sale
Price
67.05
Quantity 4,000
Value US$268,182
Karp Carol D. Officer Officer
Transaction date
Proposed sale
Price
67.01
Quantity 5,000
Value US$335,072
Karp Carol D. Chief Regulatory Officer Officer
Transaction date
Planned sale
Price
67.95
Quantity 328 -100.0%
Value US$22,288
Karp Carol D. Chief Regulatory Officer Officer
Transaction date
Planned sale
Price
66.95
Quantity 4,672 -93.4%
Value US$312,784
Zago Wagner M. Chief Scientific Officer Officer
Transaction date
Planned sale
Price
68.07
Quantity 229 -100.0%
Value US$15,589
Zago Wagner M. Chief Scientific Officer Officer
Transaction date
Planned sale
Price
66.98
Quantity 3,771 -94.3%
Value US$252,593
Malecek Michael J Officer Officer
Transaction date
Proposed sale
Price
62.33
Quantity 5,000
Value US$311,638
Malecek Michael J Chief Legal Officer Officer
Transaction date
Planned sale
Price
63.40
Quantity 620 -100.0%
Value US$39,309
Malecek Michael J Chief Legal Officer Officer
Transaction date
Planned sale
Price
62.69
Quantity 1,903 -75.4%
Value US$119,297
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Value Details
2026-08-10 2026-08-07 B Purchase Large shareholder
97,531 -33.0%
75.74
US$4,827,866
97,531 -33.0% 75.74 US$4,827,866
2026-08-10 2026-08-07 B Purchase Large shareholder
23,937 +8.7%
332.31
US$1,383,719
23,937 +8.7% 332.31 US$1,383,719
2026-07-30 2026-07-29 PlS Planned sale

Chief Strategy Officer

Officer
99,272 -2.8%
140.18
US$3,211,430
99,272 -2.8% 140.18 US$3,211,430
2026-07-30 2026-07-29 PlS Planned sale

General Counsel & Company Sec.

Officer
1,000 -19.0%
8.47
US$100,000
1,000 -19.0% 8.47 US$100,000
2026-07-29 2026-07-29 PrS Proposed sale

Officer

Officer
1,000
8.47
US$100,000
1,000 8.47 US$100,000
2026-07-29 2026-07-29 PrS Proposed sale

Officer

Officer
1,000
8.47
US$100,000
1,000 8.47 US$100,000
2026-06-18 2026-06-16 B Purchase Large shareholder
20,000 +2.7%
7.90
US$157,990
20,000 +2.7% 7.90 US$157,990
2026-06-12 2026-06-11 B Purchase Large shareholder
125,000 +13.4%
8.17
US$1,021,225
125,000 +13.4% 8.17 US$1,021,225
2026-06-09 2026-06-09 PrS Proposed sale

Previous Officer

Officer
80,000
9.25
US$740,000
80,000 9.25 US$740,000
2026-06-05 2026-06-04 B Purchase Large shareholder
50,000 +5.6%
9.31
US$465,295
50,000 +5.6% 9.31 US$465,295
2026-06-03 2026-06-02 B Purchase Large shareholder
50,000 +6.0%
9.43
US$471,300
50,000 +6.0% 9.43 US$471,300
2026-05-26 2026-05-22 B Purchase Large shareholder
100,000 +13.6%
9.81
US$981,300
100,000 +13.6% 9.81 US$981,300
2025-05-06 2025-05-06 S Sale Large shareholder
1,984,053 -27.2%
7.64
US$15,164,712
1,984,053 -27.2% 7.64 US$15,164,712
2025-05-06 2025-05-05 S Sale Large shareholder
977,693 -11.8%
8.11
US$7,930,166
977,693 -11.8% 8.11 US$7,930,166
2025-05-06 2025-05-02 S Sale Large shareholder
3,317,938 -28.6%
8.36
US$27,744,929
3,317,938 -28.6% 8.36 US$27,744,929
2025-05-02 2025-01-14 B Purchase Large shareholder
100,000 +15.7%
12.79
US$1,279,040
100,000 +15.7% 12.79 US$1,279,040
2025-05-02 2024-12-31 B Purchase Large shareholder
30,000 +4.8%
12.99
US$389,640
30,000 +4.8% 12.99 US$389,640
2025-05-02 2024-12-31 B Purchase Large shareholder
800 +0.1%
13.39
US$10,715
800 +0.1% 13.39 US$10,715
2025-05-02 2024-12-31 B Purchase Large shareholder
1,200 +0.2%
13.37
US$16,038
1,200 +0.2% 13.37 US$16,038
2025-05-02 2024-12-20 B Purchase Large shareholder
2,000 +0.3%
15.91
US$31,813
2,000 +0.3% 15.91 US$31,813
2025-05-02 2024-12-18 B Purchase Large shareholder
73,436 +6.0%
13.93
US$1,022,670
73,436 +6.0% 13.93 US$1,022,670
2024-01-24 2024-01-24 PrS Proposed sale

Officer

Officer
5,000
34.00
US$170,000
5,000 34.00 US$170,000
2024-01-24 2024-01-24 PlS Planned sale

Chief Accounting Officer

Officer
5,000 -100.0%
34.00
US$170,000
5,000 -100.0% 34.00 US$170,000
2023-12-20 2023-12-20 PrS Proposed sale

Officer

Officer
5,000
37.29
US$186,450
5,000 37.29 US$186,450
2023-12-20 2023-12-20 PlS Planned sale

Chief Accounting Officer

Officer
3,322 -100.0%
37.45
US$124,409
3,322 -100.0% 37.45 US$124,409
2023-12-20 2023-12-20 PlS Planned sale

Chief Accounting Officer

Officer
1,678 -33.6%
36.68
US$61,543
1,678 -33.6% 36.68 US$61,543
2023-11-30 2023-11-30 PrS Proposed sale

Officer

Officer
5,000
34.00
US$170,000
5,000 34.00 US$170,000
2023-11-30 2023-11-30 PlS Planned sale

Chief Accounting Officer

Officer
5,000 -100.0%
34.00
US$170,000
5,000 -100.0% 34.00 US$170,000
2023-10-25 2023-10-25 PrS Proposed sale

Officer

Officer
5,000
41.27
US$206,350
5,000 41.27 US$206,350
2023-10-25 2023-10-25 PlS Planned sale

Chief Accounting Officer

Officer
294 -100.0%
42.28
US$12,430
294 -100.0% 42.28 US$12,430
2023-10-25 2023-10-25 PlS Planned sale

Chief Accounting Officer

Officer
2,917 -90.8%
41.38
US$120,718
2,917 -90.8% 41.38 US$120,718
2023-10-25 2023-10-25 PlS Planned sale

Chief Accounting Officer

Officer
1,789 -35.8%
40.27
US$72,043
1,789 -35.8% 40.27 US$72,043
2023-10-11 2023-10-11 PrS Proposed sale

Officer

Officer
4,000
47.29
US$189,160
4,000 47.29 US$189,160
2023-10-11 2023-10-11 PlS Planned sale

Chief Operating Officer

Officer
444 -100.0%
47.74
US$21,198
444 -100.0% 47.74 US$21,198
2023-10-11 2023-10-11 PlS Planned sale

Chief Operating Officer

Officer
3,556 -88.9%
46.62
US$165,786
3,556 -88.9% 46.62 US$165,786
2023-10-04 2023-10-04 PrS Proposed sale

Officer

Officer
5,000
47.40
US$237,000
5,000 47.40 US$237,000
2023-10-04 2023-10-04 PlS Planned sale

Chief Regulatory Officer

Officer
663 -100.0%
47.29
US$31,355
663 -100.0% 47.29 US$31,355
2023-10-04 2023-10-04 PlS Planned sale

Chief Regulatory Officer

Officer
4,337 -86.7%
46.51
US$201,729
4,337 -86.7% 46.51 US$201,729
2023-09-27 2023-09-27 PrS Proposed sale

Officer

Officer
5,000
48.21
US$241,050
5,000 48.21 US$241,050
2023-09-27 2023-09-27 PlS Planned sale

Chief Legal Officer

Officer
404 -100.0%
48.31
US$19,519
404 -100.0% 48.31 US$19,519
2023-09-27 2023-09-27 PlS Planned sale

Chief Legal Officer

Officer
4,596 -91.9%
47.29
US$217,366
4,596 -91.9% 47.29 US$217,366
2023-09-25 2023-09-25 PrS Proposed sale

Director

Non-Executive Director
35,000
50.00
US$1,750,000
35,000 50.00 US$1,750,000
2023-09-19 2023-09-19 PrS Proposed sale

Officer

Officer
5,000
52.36
US$261,806
5,000 52.36 US$261,806
2023-09-19 2023-09-19 PlS Planned sale

Chief Accounting Officer

Officer
5,000 -100.0%
52.36
US$261,807
5,000 -100.0% 52.36 US$261,807
2023-09-13 2023-09-13 PrS Proposed sale

Officer

Officer
2,000
55.39
US$110,780
2,000 55.39 US$110,780
2023-09-13 2023-09-13 PrS Proposed sale

Officer

Officer
4,000
55.39
US$221,560
4,000 55.39 US$221,560
2023-09-13 2023-09-13 PlS Planned sale

Chief Operating Officer

Officer
114 -100.0%
55.96
US$6,379
114 -100.0% 55.96 US$6,379
2023-09-13 2023-09-13 PlS Planned sale

Chief Operating Officer

Officer
3,886 -97.2%
55.48
US$215,584
3,886 -97.2% 55.48 US$215,584
2023-09-13 2023-09-13 PlS Planned sale

Chief Medical Officer

Officer
2,000 -100.0%
55.48
US$110,952
2,000 -100.0% 55.48 US$110,952
2023-09-06 2023-09-06 PrS Proposed sale

Officer

Officer
5,000
54.61
US$273,050
5,000 54.61 US$273,050
2023-09-06 2023-09-06 PlS Planned sale

Chief Regulatory Officer

Officer
6 -100.0%
55.27
US$332
6 -100.0% 55.27 US$332
2023-09-06 2023-09-06 PlS Planned sale

Chief Regulatory Officer

Officer
4,994 -99.9%
54.76
US$273,472
4,994 -99.9% 54.76 US$273,472
2023-08-30 2023-08-30 PrS Proposed sale

Officer

Officer
5,000
55.01
US$275,066
5,000 55.01 US$275,066
2023-08-30 2023-08-30 PlS Planned sale

Chief Legal Officer

Officer
14 -100.0%
56.21
US$787
14 -100.0% 56.21 US$787
2023-08-30 2023-08-30 PlS Planned sale

Chief Legal Officer

Officer
2,664 -99.5%
55.39
US$147,551
2,664 -99.5% 55.39 US$147,551
2023-08-30 2023-08-30 PlS Planned sale

Chief Legal Officer

Officer
2,322 -46.4%
54.58
US$126,728
2,322 -46.4% 54.58 US$126,728
2023-08-18 2023-08-18 PrS Proposed sale

Officer

Officer
5,000
57.18
US$285,922
5,000 57.18 US$285,922
2023-08-18 2023-08-18 PlS Planned sale

Chief Accounting Officer

Officer
5,000 -100.0%
57.18
US$285,922
5,000 -100.0% 57.18 US$285,922
2023-08-16 2023-08-16 PrS Proposed sale

Officer

Officer
4,000
58.71
US$234,844
4,000 58.71 US$234,844
2023-08-16 2023-08-16 PrS Proposed sale

Officer

Officer
2,000
58.74
US$117,480
2,000 58.74 US$117,480
2023-08-16 2023-08-16 PlS Planned sale

Chief Operating Officer

Officer
401 -100.0%
59.91
US$24,025
401 -100.0% 59.91 US$24,025
2023-08-16 2023-08-16 PlS Planned sale

Chief Operating Officer

Officer
1,373 -77.4%
59.15
US$81,217
1,373 -77.4% 59.15 US$81,217
2023-08-16 2023-08-16 PlS Planned sale

Chief Operating Officer

Officer
2,226 -55.6%
58.22
US$129,602
2,226 -55.6% 58.22 US$129,602
2023-08-16 2023-08-16 PlS Planned sale

Chief Medical Officer

Officer
374 -100.0%
59.74
US$22,341
374 -100.0% 59.74 US$22,341
2023-08-16 2023-08-16 PlS Planned sale

Chief Medical Officer

Officer
748 -66.7%
58.93
US$44,079
748 -66.7% 58.93 US$44,079
2023-08-16 2023-08-16 PlS Planned sale

Chief Medical Officer

Officer
878 -43.9%
58.15
US$51,059
878 -43.9% 58.15 US$51,059
2023-08-02 2023-08-02 PrS Proposed sale

Officer

Officer
4,000
67.05
US$268,182
4,000 67.05 US$268,182
2023-08-02 2023-08-02 PrS Proposed sale

Officer

Officer
5,000
67.01
US$335,072
5,000 67.01 US$335,072
2023-08-02 2023-08-02 PlS Planned sale

Chief Regulatory Officer

Officer
328 -100.0%
67.95
US$22,288
328 -100.0% 67.95 US$22,288
2023-08-02 2023-08-02 PlS Planned sale

Chief Regulatory Officer

Officer
4,672 -93.4%
66.95
US$312,784
4,672 -93.4% 66.95 US$312,784
2023-08-02 2023-08-02 PlS Planned sale

Chief Scientific Officer

Officer
229 -100.0%
68.07
US$15,589
229 -100.0% 68.07 US$15,589
2023-08-02 2023-08-02 PlS Planned sale

Chief Scientific Officer

Officer
3,771 -94.3%
66.98
US$252,593
3,771 -94.3% 66.98 US$252,593
2023-07-26 2023-07-26 PrS Proposed sale

Officer

Officer
5,000
62.33
US$311,638
5,000 62.33 US$311,638
2023-07-26 2023-07-26 PlS Planned sale

Chief Legal Officer

Officer
620 -100.0%
63.40
US$39,309
620 -100.0% 63.40 US$39,309
2023-07-26 2023-07-26 PlS Planned sale

Chief Legal Officer

Officer
1,903 -75.4%
62.69
US$119,297
1,903 -75.4% 62.69 US$119,297