United States Biotechnology & Medical Research

Hepion Pharmaceuticals Inc (HEPA)

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On April 21, 2026, multiple key executives and stakeholders at Hepion Pharmaceuticals Inc. executed significant purchase orders. Interim CEO Gary S. Stetz, Executive Chairman Vincent S. LoPriore, and other individuals acquired substantial equity positions. These transactions represent the most recent activity recorded for the firm, reflecting notable capital deployment by leadership.
Ticker: HEPA Exchange: NAS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Hepion Pharmaceuticals Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Stetz Gary S. II Non-Executive Director
Transaction date
Purchase
Price
425.71
Quantity 93,977 -7.4%
Value US$4,388,779
Stetz Gary S. Interim CEO Executive Director
Transaction date
Purchase
Price
262.33
Quantity 88,153 -5.6%
Value US$1,846,472
1.4
Purcell Michael J. Non-Executive Director
Transaction date
Purchase
Price
17.54
Quantity 94,833 -23.9%
Value US$4,214,761
LoPriore Vincent S Executive Chairman Executive Director
Transaction date
Purchase
Price
0.05
Quantity 1,000 +14.0%
Value US$100,000
LoPriore Vincent S Executive Chairman Executive Director
Transaction date
Purchase
Price
0.05
Quantity 1,000 +128.0%
Value US$100,000
4.0
Appajosyula Sireesh Chief Operating Officer Executive Director
Transaction date
Purchase
Price
0.05
Quantity 1,000 +160.0%
Value US$100,000
1.4
Purcell Michael J. Non-Executive Director
Transaction date
Purchase
Price
0.04
Quantity 1,250,000 +inf%
Value US$50,000
Stetz Gary S. Interim CEO Executive Director
Transaction date
Purchase
Price
0.04
Quantity 1,250,000 +inf%
Value US$50,000
LoPriore Vincent S Executive Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.04
Quantity 1,250,000 +25.0%
Value US$50,000
LoPriore Vincent S Executive Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.04
Quantity 5,000,000 +inf%
Value US$200,000
4.0
Appajosyula Sireesh Non-Executive Director
Transaction date
Purchase
Price
0.04
Quantity 1,250,000 +inf%
Value US$50,000
2.4
Wijngaard Peter Non-Executive Director
Transaction date
Purchase
Price
3.05
Quantity 2,500 +35.7%
Value US$7,625
2.4
Wijngaard Peter Non-Executive Director
Transaction date
Purchase
Price
3.09
Quantity 2,500 +55.5%
Value US$7,725
2.4
Wijngaard Peter Non-Executive Director
Transaction date
Purchase
Price
5.64
Quantity 1,000 +28.6%
Value US$5,640
2.9
Foster Robert T CEO and Director Executive Director
Transaction date
Purchase
Price
5.60
Quantity 1,600 +3.3%
Value US$8,960
2.4
Wijngaard Peter Non-Executive Director
Transaction date
Purchase
Price
5.37
Quantity 861 +32.6%
Value US$4,624
2.4
Wijngaard Peter Non-Executive Director
Transaction date
Purchase
Price
5.45
Quantity 139 +5.6%
Value US$758
2.4
Wijngaard Peter Non-Executive Director
Transaction date
Purchase
Price
5.82
Quantity 1,000 +66.6%
Value US$5,820
2.9
Foster Robert T CEO,CSO and Director Executive Director
Transaction date
Purchase
Price
5.40
Quantity 1,600 +3.4%
Value US$8,640
2.9
Foster Robert T CEO and Director Executive Director
Transaction date
Purchase
Price
2.00
Quantity 20,000 +79.2%
Value US$40,000
3.2
Cavan John T Chief Financial Officer Officer
Transaction date
Purchase
Price
2.00
Quantity 10,000 +208.3%
Value US$20,000
2.4
Wijngaard Peter Non-Executive Director
Transaction date
Purchase
Price
2.20
Quantity 10,000 +50.0%
Value US$22,000
2.4
Wijngaard Peter Non-Executive Director
Transaction date
Purchase
Price
1.91
Quantity 20,000 +inf%
Value US$38,200
2.9
Foster Robert T CEO and Director Executive Director
Transaction date
Purchase
Price
1.58
Quantity 25,000 +9652.5%
Value US$39,418
3.2
BRANCACCIO JOHN P Non-Executive Director
Transaction date
Purchase
Price
1.53
Quantity 7,000 +87500.0%
Value US$10,710
3.6
JACOB GARY S Non-Executive Director
Transaction date
Purchase
Price
1.66
Quantity 12,000 +20339.0%
Value US$19,920
3.2
Cavan John T Chief Financial Officer Officer
Transaction date
Purchase
Price
1.62
Quantity 4,500 +1500.0%
Value US$7,290
Cavan John T CFO
Transaction date
Purchase
Price
0.65
Quantity 20,000 +inf%
Value US$13,000
SAPIRSTEIN JAMES Chief Executive Officer Executive Director
Transaction date
Purchase
Price
1.00
Quantity 10,000 +333.3%
Value US$10,000
SAPIRSTEIN JAMES Chief Executive Officer Executive Director
Transaction date
Purchase
Price
2.15
Quantity 500 +20.0%
Value US$1,075
SAPIRSTEIN JAMES Chief Executive Officer Executive Director
Transaction date
Purchase
Price
1.64
Quantity 2,500 +inf%
Value US$4,100
BRANCACCIO JOHN P Non-Executive Director
Transaction date
Purchase
Price
1.49
Quantity 4,393 +218.0%
Value US$6,546
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-08-12 2026-08-03 B Purchase
Stetz Gary S. II
Non-Executive Director
93,977 -7.4%
425.71
US$4,388,779 		93,977 -7.4% 425.71 US$4,388,779
2026-08-12 2026-08-03 B Purchase
Stetz Gary S.

Interim CEO

Executive Director
88,153 -5.6%
262.33
US$1,846,472 		88,153 -5.6% 262.33 US$1,846,472
2026-08-12 2026-08-03 B Purchase
1.4
Purcell Michael J.
Non-Executive Director
94,833 -23.9%
17.54
US$4,214,761 		94,833 -23.9% 17.54 US$4,214,761
2026-08-12 2026-08-03 B Purchase
LoPriore Vincent S

Executive Chairman

Executive Director
1,000 +14.0%
0.05
US$100,000 		1,000 +14.0% 0.05 US$100,000
2026-08-12 2026-08-03 B Purchase
LoPriore Vincent S

Executive Chairman

Executive Director
1,000 +128.0%
0.05
US$100,000 		1,000 +128.0% 0.05 US$100,000
2026-08-12 2026-08-03 B Purchase
4.0
Appajosyula Sireesh

Chief Operating Officer

Executive Director
1,000 +160.0%
0.05
US$100,000 		1,000 +160.0% 0.05 US$100,000
2026-04-27 2026-04-21 B Purchase
1.4
Purcell Michael J.
Non-Executive Director
1,250,000 +inf%
0.04
US$50,000 		1,250,000 +inf% 0.04 US$50,000
2026-04-27 2026-04-21 B Purchase
Stetz Gary S.

Interim CEO

Executive Director
1,250,000 +inf%
0.04
US$50,000 		1,250,000 +inf% 0.04 US$50,000
2026-04-27 2026-04-21 B Purchase
LoPriore Vincent S

Executive Chairman

Executive Director Large shareholder
1,250,000 +25.0%
0.04
US$50,000 		1,250,000 +25.0% 0.04 US$50,000
2026-04-27 2026-04-21 B Purchase
LoPriore Vincent S

Executive Chairman

Executive Director Large shareholder
5,000,000 +inf%
0.04
US$200,000 		5,000,000 +inf% 0.04 US$200,000
2026-04-27 2026-04-21 B Purchase
4.0
Appajosyula Sireesh
Non-Executive Director
1,250,000 +inf%
0.04
US$50,000 		1,250,000 +inf% 0.04 US$50,000
2023-11-28 2023-11-27 B Purchase
2.4
Wijngaard Peter
Non-Executive Director
2,500 +35.7%
3.05
US$7,625 		2,500 +35.7% 3.05 US$7,625
2023-11-28 2023-11-24 B Purchase
2.4
Wijngaard Peter
Non-Executive Director
2,500 +55.5%
3.09
US$7,725 		2,500 +55.5% 3.09 US$7,725
2023-09-20 2023-09-19 B Purchase
2.4
Wijngaard Peter
Non-Executive Director
1,000 +28.6%
5.64
US$5,640 		1,000 +28.6% 5.64 US$5,640
2023-09-19 2023-09-18 B Purchase
2.9
Foster Robert T

CEO and Director

Executive Director
1,600 +3.3%
5.60
US$8,960 		1,600 +3.3% 5.60 US$8,960
2023-09-20 2023-09-15 B Purchase
2.4
Wijngaard Peter
Non-Executive Director
861 +32.6%
5.37
US$4,624 		861 +32.6% 5.37 US$4,624
2023-09-20 2023-09-15 B Purchase
2.4
Wijngaard Peter
Non-Executive Director
139 +5.6%
5.45
US$758 		139 +5.6% 5.45 US$758
2023-09-20 2023-09-15 B Purchase
2.4
Wijngaard Peter
Non-Executive Director
1,000 +66.6%
5.82
US$5,820 		1,000 +66.6% 5.82 US$5,820
2023-09-18 2023-09-15 B Purchase
2.9
Foster Robert T

CEO,CSO and Director

Executive Director
1,600 +3.4%
5.40
US$8,640 		1,600 +3.4% 5.40 US$8,640
2021-02-18 2021-02-18 B Purchase
2.9
Foster Robert T

CEO and Director

Executive Director
20,000 +79.2%
2.00
US$40,000 		20,000 +79.2% 2.00 US$40,000
2021-02-18 2021-02-18 B Purchase
3.2
Cavan John T

Chief Financial Officer

Officer
10,000 +208.3%
2.00
US$20,000 		10,000 +208.3% 2.00 US$20,000
2021-02-18 2021-02-16 B Purchase
2.4
Wijngaard Peter
Non-Executive Director
10,000 +50.0%
2.20
US$22,000 		10,000 +50.0% 2.20 US$22,000
2020-12-21 2020-12-18 B Purchase
2.4
Wijngaard Peter
Non-Executive Director
20,000 +inf%
1.91
US$38,200 		20,000 +inf% 1.91 US$38,200
2020-12-08 2020-12-08 B Purchase
2.9
Foster Robert T

CEO and Director

Executive Director
25,000 +9652.5%
1.58
US$39,418 		25,000 +9652.5% 1.58 US$39,418
2020-12-02 2020-12-02 B Purchase
3.2
BRANCACCIO JOHN P
Non-Executive Director
7,000 +87500.0%
1.53
US$10,710 		7,000 +87500.0% 1.53 US$10,710
2020-12-01 2020-12-01 B Purchase
3.6
JACOB GARY S
Non-Executive Director
12,000 +20339.0%
1.66
US$19,920 		12,000 +20339.0% 1.66 US$19,920
2020-11-30 2020-11-25 B Purchase
3.2
Cavan John T

Chief Financial Officer

Officer
4,500 +1500.0%
1.62
US$7,290 		4,500 +1500.0% 1.62 US$7,290
2017-06-22 2017-06-20 B Purchase Cavan John T

CFO
20,000 +inf%
0.65
US$13,000 		20,000 +inf% 0.65 US$13,000
2016-02-18 2016-02-18 B Purchase SAPIRSTEIN JAMES

Chief Executive Officer

Executive Director
10,000 +333.3%
1.00
US$10,000 		10,000 +333.3% 1.00 US$10,000
2015-12-01 2015-11-30 B Purchase SAPIRSTEIN JAMES

Chief Executive Officer

Executive Director
500 +20.0%
2.15
US$1,075 		500 +20.0% 2.15 US$1,075
2015-11-24 2015-11-23 B Purchase SAPIRSTEIN JAMES

Chief Executive Officer

Executive Director
2,500 +inf%
1.64
US$4,100 		2,500 +inf% 1.64 US$4,100
2014-03-07 2014-03-04 B Purchase BRANCACCIO JOHN P Non-Executive Director
4,393 +218.0%
1.49
US$6,546 		4,393 +218.0% 1.49 US$6,546
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