Advanced Proteome Therapeutics Corporation

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Woodward, Paul John Courtney

Director of Issuer, Senior Officer of Issuer

1 purchase — total 72,500 CAD

Buy 23 Dec 2022

Value CA$3,293,857.25 | Price 319.83 | Shares 38,144

Woodward, Paul John Courtney

Director of Issuer, Senior Officer of Issuer

1 purchase — total 560 CAD

Buy 22 Dec 2022

Value CA$885,315.37 | Price 210.12 | Shares 59,852

Woodward, Paul John Courtney

Director of Issuer, Senior Officer of Issuer

1 purchase — total 630 CAD

Buy 21 Dec 2022

Value CA$630.00 | Price 0.04 | Shares 18,000

Woodward, Paul John Courtney

Director of Issuer, Senior Officer of Issuer

1 purchase — total 450 CAD

Buy 15 Dec 2022

Value CA$450.00 | Price 0.03 | Shares 15,000

Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Insider and/or position	Nb. shares Price Value	Number of shares	Price	Value
2022-12-23	2022-12-23	B Purchase	3.7 Woodward, Paul John Courtney Director of Issuer, Senior Officer of Issuer Executive Director	38,144 -10.2% 319.83 CA$3,293,857	38,144 -10.2%	319.83	CA$3,293,857
2022-12-22	2022-12-22	B Purchase	3.7 Woodward, Paul John Courtney Director of Issuer, Senior Officer of Issuer Executive Director	59,852 +40.0% 210.12 CA$885,315	59,852 +40.0%	210.12	CA$885,315
2022-12-21	2022-12-21	B Purchase	3.7 Woodward, Paul John Courtney Director of Issuer, Senior Officer of Issuer Executive Director	44,597 +36.9% 161.59 CA$4,426,599	44,597 +36.9%	161.59	CA$4,426,599
2022-12-15	2022-12-15	B Purchase	3.7 Woodward, Paul John Courtney Director of Issuer, Senior Officer of Issuer Executive Director	15,000 +1.3% 0.03 CA$450	15,000 +1.3%	0.03	CA$450

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