|
2025-04-14 |
2025-04-10 |
S
Venta
|
Gran accionista
|
92 177
+43.6%
207,72
4.712.996 US$
|
92 177
+43.6%
|
207,72
|
4.712.996 US$
|
|
|
2025-04-14 |
2025-04-10 |
S
Venta
|
Gran accionista
|
13 906
-20.0%
218,60
4.221.897 US$
|
13 906
-20.0%
|
218,60
|
4.221.897 US$
|
|
|
2023-11-17 |
2023-11-17 |
B
Compra
|
Chief Commercial Officer
Oficial
|
77 288
-23.4%
103,57
4.536.954 US$
|
77 288
-23.4%
|
103,57
|
4.536.954 US$
|
|
|
2023-01-19 |
2023-01-18 |
Por favor
Venta prevista
|
Chief Financial Officer
Oficial
|
8 673
-2.1%
0,61
5.283 US$
|
8 673
-2.1%
|
0,61
|
5.283 US$
|
|
|
2022-10-20 |
2022-10-19 |
Por favor
Venta prevista
|
President and CEO
Consejero ejecutivo
|
51 100
-3.3%
0,62
31.820 US$
|
51 100
-3.3%
|
0,62
|
31.820 US$
|
|
|
2022-10-20 |
2022-10-18 |
Por favor
Venta prevista
|
President and CEO
Consejero ejecutivo
|
80 000
-4.9%
0,68
54.008 US$
|
80 000
-4.9%
|
0,68
|
54.008 US$
|
|
|
2022-10-11 |
2022-10-07 |
B
Compra
|
Consejero no ejecutivo
|
2 264 861
+63.2%
0,48
1.087.133 US$
|
2 264 861
+63.2%
|
0,48
|
1.087.133 US$
|
|
|
2022-08-17 |
2022-08-17 |
Por favor
Venta prevista
|
Chief Financial Officer
Oficial
|
1 270
-0.3%
0,48
605 US$
|
1 270
-0.3%
|
0,48
|
605 US$
|
|
|
2022-08-17 |
2022-08-17 |
Por favor
Venta prevista
|
Chief Commercial Officer
Oficial
|
4 300
-0.6%
0,48
2.049 US$
|
4 300
-0.6%
|
0,48
|
2.049 US$
|
|
|
2022-08-17 |
2022-08-16 |
Por favor
Venta prevista
|
Chief Financial Officer
Oficial
|
5 100
-1.2%
0,48
2.460 US$
|
5 100
-1.2%
|
0,48
|
2.460 US$
|
|
|
2022-08-17 |
2022-08-16 |
Por favor
Venta prevista
|
Chief Commercial Officer
Oficial
|
18 700
-2.6%
0,49
9.172 US$
|
18 700
-2.6%
|
0,49
|
9.172 US$
|
|
|
2018-02-26 |
2018-02-14 |
B
Compra
|
Eggenberg Michael
Consejero no ejecutivo
Gran accionista
|
342 132
+11.5%
7,20
2.463.350 US$
|
342 132
+11.5%
|
7,20
|
2.463.350 US$
|
|
|
2018-02-26 |
2018-02-14 |
B
Compra
|
Eggenberg Michael
Consejero no ejecutivo
Gran accionista
|
603 687
+11.4%
7,20
4.346.546 US$
|
603 687
+11.4%
|
7,20
|
4.346.546 US$
|
|
|
2018-02-26 |
2018-02-14 |
B
Compra
|
Rizzo Matthew
Consejero no ejecutivo
Gran accionista
|
342 132
+11.5%
7,20
2.463.350 US$
|
342 132
+11.5%
|
7,20
|
2.463.350 US$
|
|
|
2018-02-26 |
2018-02-14 |
B
Compra
|
Rizzo Matthew
Consejero no ejecutivo
Gran accionista
|
603 687
+11.4%
7,20
4.346.546 US$
|
603 687
+11.4%
|
7,20
|
4.346.546 US$
|
|
|
2018-02-23 |
2018-02-14 |
B
Compra
|
ORBIMED ADVISORS LLC
Consejero no ejecutivo
Gran accionista
|
342 132
+11.5%
7,20
2.463.350 US$
|
342 132
+11.5%
|
7,20
|
2.463.350 US$
|
|
|
2018-02-23 |
2018-02-14 |
B
Compra
|
ORBIMED ADVISORS LLC
Consejero no ejecutivo
Gran accionista
|
603 687
+11.4%
7,20
4.346.546 US$
|
603 687
+11.4%
|
7,20
|
4.346.546 US$
|
|
|
2016-05-10 |
2016-05-09 |
B
Compra
|
Goldberger Daniel S
Chief Executive Officer
Consejero ejecutivo
|
5 000
+6.1%
2,34
11.700 US$
|
5 000
+6.1%
|
2,34
|
11.700 US$
|
|
|
2015-12-03 |
2015-12-03 |
B
Compra
|
Swanson Kent L
Consejero no ejecutivo
|
1 000
+1.2%
2,83
2.830 US$
|
1 000
+1.2%
|
2,83
|
2.830 US$
|
|
|
2015-12-03 |
2015-12-03 |
B
Compra
|
Swanson Kent L
Consejero no ejecutivo
|
1 000
+1.2%
2,82
2.820 US$
|
1 000
+1.2%
|
2,82
|
2.820 US$
|
|
|
2015-12-03 |
2015-12-03 |
B
Compra
|
Swanson Kent L
Consejero no ejecutivo
|
300
+0.4%
2,81
843 US$
|
300
+0.4%
|
2,81
|
843 US$
|
|
|
2015-12-03 |
2015-12-01 |
B
Compra
|
Swanson Kent L
Consejero no ejecutivo
|
1 000
+1.3%
2,85
2.850 US$
|
1 000
+1.3%
|
2,85
|
2.850 US$
|
|
|
2015-11-23 |
2015-11-20 |
B
Compra
|
Kirschman David Louis
EVP & Chief Scientific Officer
Consejero ejecutivo
Gran accionista
|
1 000
+0.1%
3,04
3.040 US$
|
1 000
+0.1%
|
3,04
|
3.040 US$
|
|
|
2015-11-23 |
2015-11-20 |
B
Compra
|
Kirschman David Louis
EVP & Chief Scientific Officer
Consejero ejecutivo
Gran accionista
|
1 000
+0.1%
2,94
2.943 US$
|
1 000
+0.1%
|
2,94
|
2.943 US$
|
|
|
2015-11-20 |
2015-11-20 |
B
Compra
|
Swanson Kent L
Consejero no ejecutivo
|
4 976
+6.6%
3,00
14.928 US$
|
4 976
+6.6%
|
3,00
|
14.928 US$
|
|
|
2015-11-20 |
2015-11-19 |
B
Compra
|
Swanson Kent L
Consejero no ejecutivo
|
24
+0.0%
2,90
70 US$
|
24
+0.0%
|
2,90
|
70 US$
|
|
|
2015-11-19 |
2015-11-19 |
B
Compra
|
Kirschman David Louis
EVP & Chief Scientific Officer
Consejero ejecutivo
Gran accionista
|
1 000
+0.1%
2,94
2.943 US$
|
1 000
+0.1%
|
2,94
|
2.943 US$
|
|
|
2015-11-19 |
2015-11-18 |
B
Compra
|
Kirschman David Louis
EVP & Chief Scientific Officer
Consejero ejecutivo
Gran accionista
|
1 000
+0.1%
2,86
2.862 US$
|
1 000
+0.1%
|
2,86
|
2.862 US$
|
|
|
2015-11-16 |
2015-11-16 |
B
Compra
|
Goldberger Daniel S
Chief Executive Officer
Consejero ejecutivo
|
3 000
+24.0%
2,80
8.400 US$
|
3 000
+24.0%
|
2,80
|
8.400 US$
|
|
|
2015-09-09 |
2015-09-04 |
B
Compra
|
WICKWIRE JON M.
Consejero no ejecutivo
|
10 869
+53.3%
3,68
39.998 US$
|
10 869
+53.3%
|
3,68
|
39.998 US$
|
|
|
2015-09-09 |
2015-09-04 |
B
Compra
|
Goldberger Daniel S
Chief Executive Officer
Consejero ejecutivo
|
81 522
+inf%
3,68
300.001 US$
|
81 522
+inf%
|
3,68
|
300.001 US$
|
|
|
2015-09-09 |
2015-09-04 |
B
Compra
|
DEEDRICK JOHN ARTHUR
Consejero no ejecutivo
|
6 793
+69.1%
3,68
24.998 US$
|
6 793
+69.1%
|
3,68
|
24.998 US$
|
|
|
2015-09-09 |
2015-09-04 |
B
Compra
|
LOPACH MICHAEL A
Consejero no ejecutivo
|
10 869
+320.7%
3,68
39.998 US$
|
10 869
+320.7%
|
3,68
|
39.998 US$
|
|
|
2015-09-09 |
2015-09-04 |
B
Compra
|
Swanson Kent L
Consejero no ejecutivo
|
30 000
+66.9%
3,68
110.400 US$
|
30 000
+66.9%
|
3,68
|
110.400 US$
|
|
|
2014-07-21 |
2014-06-10 |
S
Venta
|
HOLMES DARREL LEE
COO
Oficial
|
50 000
-81.1%
0,74
37.000 US$
|
50 000
-81.1%
|
0,74
|
37.000 US$
|
|
|
2014-05-22 |
2014-05-22 |
B
Compra
|
Goldberger Daniel S
President and CEO
Consejero ejecutivo
|
25 000
+25.0%
0,65
16.250 US$
|
25 000
+25.0%
|
0,65
|
16.250 US$
|
|
|
2014-05-20 |
2014-05-20 |
B
Compra
|
JUDA GREGORY ALEXANDER
Chief Scientific Officer
Oficial
|
20 000
+100.0%
0,69
13.796 US$
|
20 000
+100.0%
|
0,69
|
13.796 US$
|
|
|
2014-05-09 |
2014-05-07 |
S
Venta
|
COOK GUY S
Gran accionista
|
365 000
-23.3%
0,66
240.900 US$
|
365 000
-23.3%
|
0,66
|
240.900 US$
|
|
|
2014-05-09 |
2014-05-07 |
S
Venta
|
COOK GUY S
Gran accionista
|
500 000
-27.8%
0,66
330.000 US$
|
500 000
-27.8%
|
0,66
|
330.000 US$
|
|
|
2014-05-09 |
2014-05-07 |
S
Venta
|
COOK GUY S
Gran accionista
|
500 000
-27.8%
0,66
330.000 US$
|
500 000
-27.8%
|
0,66
|
330.000 US$
|
|
|
2014-05-07 |
2014-05-06 |
S
Venta
|
COOK GUY S
Gran accionista
|
135 000
-7.9%
0,75
101.534 US$
|
135 000
-7.9%
|
0,75
|
101.534 US$
|
|
|
2014-05-07 |
2014-05-06 |
S
Venta
|
COOK GUY S
Gran accionista
|
725 000
-24.3%
0,75
545.272 US$
|
725 000
-24.3%
|
0,75
|
545.272 US$
|
|
|
2014-05-07 |
2014-05-05 |
S
Venta
|
COOK GUY S
Gran accionista
|
25 000
-0.8%
0,74
18.505 US$
|
25 000
-0.8%
|
0,74
|
18.505 US$
|
|
|
2014-05-05 |
2014-05-02 |
S
Venta
|
COOK GUY S
Gran accionista
|
230 000
-7.1%
0,73
167.785 US$
|
230 000
-7.1%
|
0,73
|
167.785 US$
|
|
|
2014-05-05 |
2014-05-01 |
S
Venta
|
COOK GUY S
Gran accionista
|
50 000
-1.5%
0,71
35.420 US$
|
50 000
-1.5%
|
0,71
|
35.420 US$
|
|
|
2014-05-01 |
2014-04-30 |
S
Venta
|
COOK GUY S
Gran accionista
|
40 000
-1.2%
0,70
28.008 US$
|
40 000
-1.2%
|
0,70
|
28.008 US$
|
|
|
2014-05-01 |
2014-04-29 |
S
Venta
|
COOK GUY S
Gran accionista
|
45 000
-1.3%
0,70
31.500 US$
|
45 000
-1.3%
|
0,70
|
31.500 US$
|
|
|
2014-04-29 |
2014-04-25 |
S
Venta
|
COOK GUY S
Gran accionista
|
100 000
-2.9%
0,70
70.110 US$
|
100 000
-2.9%
|
0,70
|
70.110 US$
|
|
|
2014-04-25 |
2014-04-24 |
S
Venta
|
COOK GUY S
Gran accionista
|
130 000
-3.6%
0,71
91.793 US$
|
130 000
-3.6%
|
0,71
|
91.793 US$
|
|
|
2014-04-25 |
2014-04-23 |
S
Venta
|
COOK GUY S
Gran accionista
|
260 000
-6.7%
0,70
182.494 US$
|
260 000
-6.7%
|
0,70
|
182.494 US$
|
|
|
2014-04-23 |
2014-04-22 |
S
Venta
|
COOK GUY S
Gran accionista
|
270 000
-6.5%
0,71
192.726 US$
|
270 000
-6.5%
|
0,71
|
192.726 US$
|
|
|
2014-04-23 |
2014-04-21 |
S
Venta
|
COOK GUY S
Gran accionista
|
140 000
-3.3%
0,70
98.448 US$
|
140 000
-3.3%
|
0,70
|
98.448 US$
|
|
|
2014-04-21 |
2014-04-17 |
S
Venta
|
COOK GUY S
Gran accionista
|
75 000
-1.7%
0,70
52.500 US$
|
75 000
-1.7%
|
0,70
|
52.500 US$
|
|
|
2014-04-10 |
2014-04-09 |
S
Venta
|
COOK GUY S
Gran accionista
|
100 000
-2.2%
0,71
70.870 US$
|
100 000
-2.2%
|
0,71
|
70.870 US$
|
|
|
2014-04-10 |
2014-04-08 |
S
Venta
|
COOK GUY S
Gran accionista
|
310 000
-6.5%
0,72
223.820 US$
|
310 000
-6.5%
|
0,72
|
223.820 US$
|
|
|
2014-01-17 |
2014-01-15 |
B
Compra
|
COOK GUY S
Gran accionista
|
160 000
+3.5%
0,64
102.816 US$
|
160 000
+3.5%
|
0,64
|
102.816 US$
|
|
|
2014-01-08 |
2014-01-07 |
S
Venta
|
COOK GUY S
Gran accionista
|
273 300
-5.6%
0,53
144.849 US$
|
273 300
-5.6%
|
0,53
|
144.849 US$
|
|
|
2013-12-30 |
2013-12-26 |
S
Venta
|
COOK GUY S
Gran accionista
|
64 380
-1.3%
0,53
34.179 US$
|
64 380
-1.3%
|
0,53
|
34.179 US$
|
|
|
2013-12-26 |
2013-12-24 |
S
Venta
|
COOK GUY S
Gran accionista
|
100 000
-5.3%
0,44
44.000 US$
|
100 000
-5.3%
|
0,44
|
44.000 US$
|
|
|
2013-12-26 |
2013-12-24 |
S
Venta
|
COOK GUY S
Gran accionista
|
100 000
-5.3%
0,44
44.000 US$
|
100 000
-5.3%
|
0,44
|
44.000 US$
|
|
|
2013-12-26 |
2013-12-24 |
S
Venta
|
COOK GUY S
Gran accionista
|
100 000
-5.6%
0,44
44.000 US$
|
100 000
-5.6%
|
0,44
|
44.000 US$
|
|
|
2013-12-13 |
2013-12-11 |
S
Venta
|
COOK GUY S
Gran accionista
|
160 000
-3.1%
0,42
67.536 US$
|
160 000
-3.1%
|
0,42
|
67.536 US$
|
|
|
2013-11-20 |
2013-11-19 |
B
Compra
|
JUDA GREGORY ALEXANDER
Chief Scientific Officer
Oficial
|
20 000
+inf%
0,45
9.000 US$
|
20 000
+inf%
|
0,45
|
9.000 US$
|
|
|
2013-11-15 |
2013-11-12 |
B
Compra
|
Goldberger Daniel S
President and CEO
Consejero ejecutivo
|
50 000
+99.8%
0,48
24.050 US$
|
50 000
+99.8%
|
0,48
|
24.050 US$
|
|
|
2013-10-01 |
2013-09-30 |
S
Venta
|
COOK GUY S
Gran accionista
|
137 000
-2.6%
0,64
87.570 US$
|
137 000
-2.6%
|
0,64
|
87.570 US$
|
|
|
2013-09-24 |
2013-09-20 |
S
Venta
|
COOK GUY S
Gran accionista
|
30 000
-0.6%
0,60
18.000 US$
|
30 000
-0.6%
|
0,60
|
18.000 US$
|
|
|
2013-09-16 |
2013-09-13 |
S
Venta
|
HOLMES DARREL LEE
COO
Oficial
|
30 000
-100.0%
0,57
17.100 US$
|
30 000
-100.0%
|
0,57
|
17.100 US$
|
|
|
2013-08-28 |
2013-08-28 |
S
Venta
|
COOK GUY S
Gran accionista
|
100 000
-5.0%
0,56
55.960 US$
|
100 000
-5.0%
|
0,56
|
55.960 US$
|
|
|
2013-08-28 |
2013-08-28 |
S
Venta
|
COOK GUY S
Gran accionista
|
100 000
-5.0%
0,56
55.960 US$
|
100 000
-5.0%
|
0,56
|
55.960 US$
|
|
|
2013-08-28 |
2013-08-28 |
S
Venta
|
COOK GUY S
Gran accionista
|
200 000
-10.0%
0,56
111.920 US$
|
200 000
-10.0%
|
0,56
|
111.920 US$
|
|
|
2013-08-27 |
2013-08-26 |
B
Compra
|
Goldberger Daniel S
President and CEO
Consejero ejecutivo
|
20 000
+66.4%
0,60
12.000 US$
|
20 000
+66.4%
|
0,60
|
12.000 US$
|
|
|
2013-08-20 |
2013-08-19 |
B
Compra
|
Goldberger Daniel S
President and CEO
Consejero ejecutivo
|
16 194
+117.3%
0,59
9.554 US$
|
16 194
+117.3%
|
0,59
|
9.554 US$
|
|
|
2013-08-19 |
2013-08-16 |
B
Compra
|
Goldberger Daniel S
President and CEO
Consejero ejecutivo
|
13 806
+inf%
0,58
8.042 US$
|
13 806
+inf%
|
0,58
|
8.042 US$
|
|
|
2013-06-20 |
2013-06-18 |
S
Venta
|
COOK GUY S
Gran accionista
|
372 859
-6.6%
0,52
195.005 US$
|
372 859
-6.6%
|
0,52
|
195.005 US$
|
|
|
2013-06-14 |
2013-06-13 |
B
Compra
|
Swanson Kent L
Consejero no ejecutivo
|
100 000
+40.0%
0,55
55.000 US$
|
100 000
+40.0%
|
0,55
|
55.000 US$
|
|