|
2022-06-29 |
2022-06-28 |
S
Venta
|
SVP, CFO
Oficial
|
36 415
+39.2%
396,44
941.474 US$
|
36 415
+39.2%
|
396,44
|
941.474 US$
|
|
|
2021-06-28 |
2021-06-28 |
B
Compra
|
President & CEO
Consejero ejecutivo
|
40 610
+42.0%
226,96
4.657.848 US$
|
40 610
+42.0%
|
226,96
|
4.657.848 US$
|
|
|
2019-06-04 |
2019-05-31 |
B
Compra
|
VP Fin,Princ Fin&Acct Officer
|
92 743
+35.1%
42,17
227.258 US$
|
92 743
+35.1%
|
42,17
|
227.258 US$
|
|
|
2019-02-05 |
2019-02-01 |
B
Compra
|
President & CEO
Consejero ejecutivo
|
50 000
+1250.0%
1,02
51.000 US$
|
50 000
+1250.0%
|
1,02
|
51.000 US$
|
|
|
2019-02-04 |
2019-02-01 |
B
Compra
|
Consejero no ejecutivo
|
100 000
+inf%
1,02
102.000 US$
|
100 000
+inf%
|
1,02
|
102.000 US$
|
|
|
2018-03-23 |
2018-03-22 |
S
Venta
|
Habib Yacoub
SVP, Bus Dev & Corp Planning
|
5 000
-100.0%
1,76
8.800 US$
|
5 000
-100.0%
|
1,76
|
8.800 US$
|
|
|
2017-02-14 |
2017-02-10 |
Por favor
Venta prevista
|
Lark Michael W.
Sr. VP, Research & CSO
|
23 699
-24.1%
8,00
189.592 US$
|
23 699
-24.1%
|
8,00
|
189.592 US$
|
|
|
2016-11-10 |
2016-11-09 |
B
Compra
|
Bourdow Carrie L.
SVP, Chief Commercial Officer
Oficial
|
4 000
+800.0%
4,34
17.360 US$
|
4 000
+800.0%
|
4,34
|
17.360 US$
|
|
|
2016-11-09 |
2016-11-07 |
B
Compra
|
Habib Yacoub
SVP, Bus Dev & Corp Planning
Oficial
|
5 000
+inf%
4,12
20.600 US$
|
5 000
+inf%
|
4,12
|
20.600 US$
|
|
|
2016-11-09 |
2016-11-07 |
B
Compra
|
GOWEN MAXINE
President & CEO
Consejero ejecutivo
|
12 500
+312.5%
4,10
51.250 US$
|
12 500
+312.5%
|
4,10
|
51.250 US$
|
|
|
2016-05-31 |
2016-05-27 |
B
Compra
|
GOWEN MAXINE
President & CEO
Consejero ejecutivo
|
14 084
+5.0%
7,08
99.715 US$
|
14 084
+5.0%
|
7,08
|
99.715 US$
|
|
|
2016-05-31 |
2016-05-26 |
B
Compra
|
GOWEN MAXINE
President & CEO
Consejero ejecutivo
|
4 000
+inf%
7,20
28.800 US$
|
4 000
+inf%
|
7,20
|
28.800 US$
|
|
|
2016-05-31 |
2016-05-26 |
B
Compra
|
GOWEN MAXINE
President & CEO
Consejero ejecutivo
|
4 000
+1.5%
7,19
28.760 US$
|
4 000
+1.5%
|
7,19
|
28.760 US$
|
|
|
2014-12-15 |
2014-12-12 |
B
Compra
|
Limongelli John M
Sr. VP,General Counsel & Secy
Oficial
|
3 000
+33.3%
4,14
12.420 US$
|
3 000
+33.3%
|
4,14
|
12.420 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
MOULDER LEON O JR
Consejero no ejecutivo
|
19 800
+65.6%
4,06
80.388 US$
|
19 800
+65.6%
|
4,06
|
80.388 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
New Enterprise Associates 12, Limited Partnership
Gran accionista
|
1 000 000
+26.2%
4,00
4.000.000 US$
|
1 000 000
+26.2%
|
4,00
|
4.000.000 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
Lark Michael W.
Sr. VP, Research & CSO
Oficial
|
5 000
+6.2%
4,00
20.000 US$
|
5 000
+6.2%
|
4,00
|
20.000 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
Limongelli John M
Sr. VP,General Counsel & Secy
Oficial
|
9 000
+inf%
4,00
36.000 US$
|
9 000
+inf%
|
4,00
|
36.000 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
Soergel David
Sr. VP, Clinical Development
Oficial
|
1 250
+4.6%
4,00
5.000 US$
|
1 250
+4.6%
|
4,00
|
5.000 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
Alta Partners VIII, L.P.
Gran accionista
|
500 000
+12.9%
4,00
2.000.000 US$
|
500 000
+12.9%
|
4,00
|
2.000.000 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
Yanni Barbara
Consejero no ejecutivo
|
1 250
+inf%
4,00
5.000 US$
|
1 250
+inf%
|
4,00
|
5.000 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
GOWEN MAXINE
President & CEO
Consejero ejecutivo
|
8 000
+2.5%
4,00
32.000 US$
|
8 000
+2.5%
|
4,00
|
32.000 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
DOUGHERTY MICHAEL R
Consejero no ejecutivo
|
7 000
+inf%
4,00
28.000 US$
|
7 000
+inf%
|
4,00
|
28.000 US$
|
|
|
2014-12-10 |
2014-12-10 |
B
Compra
|
Cuca Roberto
Sr. VP and CFO
Oficial
|
25 000
+inf%
4,00
100.000 US$
|
25 000
+inf%
|
4,00
|
100.000 US$
|
|
|
2014-12-10 |
2014-12-09 |
B
Compra
|
MOULDER LEON O JR
Consejero no ejecutivo
|
30 200
+inf%
3,96
119.592 US$
|
30 200
+inf%
|
3,96
|
119.592 US$
|
|
|
2014-08-18 |
2014-08-14 |
S
Venta
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
354
-1.0%
6,04
2.138 US$
|
354
-1.0%
|
6,04
|
2.138 US$
|
|
|
2014-08-18 |
2014-08-14 |
S
Venta
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
243
-1.0%
6,04
1.468 US$
|
243
-1.0%
|
6,04
|
1.468 US$
|
|
|
2014-08-18 |
2014-08-14 |
S
Venta
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
690
-1.0%
6,04
4.168 US$
|
690
-1.0%
|
6,04
|
4.168 US$
|
|
|
2014-08-18 |
2014-08-14 |
S
Venta
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
35 415
-1.0%
6,04
213.907 US$
|
35 415
-1.0%
|
6,04
|
213.907 US$
|
|
|
2014-08-15 |
2014-08-13 |
S
Venta
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
55
-0.1%
6,12
337 US$
|
55
-0.1%
|
6,12
|
337 US$
|
|
|
2014-08-15 |
2014-08-13 |
S
Venta
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
38
-0.2%
6,12
233 US$
|
38
-0.2%
|
6,12
|
233 US$
|
|
|
2014-08-15 |
2014-08-13 |
S
Venta
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
107
-0.1%
6,12
655 US$
|
107
-0.1%
|
6,12
|
655 US$
|
|
|
2014-08-15 |
2014-08-13 |
S
Venta
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
5 500
-0.1%
6,12
33.660 US$
|
5 500
-0.1%
|
6,12
|
33.660 US$
|
|
|
2014-02-07 |
2014-02-05 |
B
Compra
|
Forest Laboratories Holdings Ltd
Gran accionista
|
428 571
+14.5%
7,00
2.999.997 US$
|
428 571
+14.5%
|
7,00
|
2.999.997 US$
|
|
|
2014-02-07 |
2014-02-05 |
B
Compra
|
HealthCare Ventures VIII, L.P.
Gran accionista
|
297 058
+13.8%
7,00
2.079.406 US$
|
297 058
+13.8%
|
7,00
|
2.079.406 US$
|
|
|
2014-02-07 |
2014-02-05 |
B
Compra
|
Alta Partners VIII, L.P.
Gran accionista
|
472 410
+13.8%
7,00
3.306.870 US$
|
472 410
+13.8%
|
7,00
|
3.306.870 US$
|
|
|
2014-02-07 |
2014-02-05 |
B
Compra
|
Polaris Venture Management Co. V, L.L.C.
Gran accionista
|
472 405
+14.1%
7,00
3.306.835 US$
|
472 405
+14.1%
|
7,00
|
3.306.835 US$
|
|
|
2014-02-07 |
2014-02-05 |
B
Compra
|
New Enterprise Associates 12, Limited Partnership
Gran accionista
|
472 410
+14.1%
7,00
3.306.870 US$
|
472 410
+14.1%
|
7,00
|
3.306.870 US$
|
|