|
2019-12-12 |
2019-12-12 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
38 424
-11.1%
426,36
2.716.053 US$
|
38 424
-11.1%
|
426,36
|
2.716.053 US$
|
|
|
2019-12-12 |
2019-12-11 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
62 142
+40.0%
50,33
100.488 US$
|
62 142
+40.0%
|
50,33
|
100.488 US$
|
|
|
2019-12-12 |
2019-12-10 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
90 213
+23.3%
193,69
4.937.356 US$
|
90 213
+23.3%
|
193,69
|
4.937.356 US$
|
|
|
2019-12-09 |
2019-12-09 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
4 500
+0.1%
0,70
3.150 US$
|
4 500
+0.1%
|
0,70
|
3.150 US$
|
|
|
2019-12-09 |
2019-12-06 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
40
+0.0%
0,70
28 US$
|
40
+0.0%
|
0,70
|
28 US$
|
|
|
2019-12-09 |
2019-12-05 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
5 160
+0.1%
0,70
3.612 US$
|
5 160
+0.1%
|
0,70
|
3.612 US$
|
|
|
2019-11-26 |
2019-11-22 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
89 845
+2.4%
0,75
67.033 US$
|
89 845
+2.4%
|
0,75
|
67.033 US$
|
|
|
2019-10-16 |
2019-10-11 |
B
Compra
|
Gran accionista
|
100 000
+2.7%
0,65
64.900 US$
|
100 000
+2.7%
|
0,65
|
64.900 US$
|
|
|
2018-12-27 |
2018-12-27 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
100 000
-6.3%
0,85
85.140 US$
|
100 000
-6.3%
|
0,85
|
85.140 US$
|
|
|
2018-12-27 |
2018-12-27 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
56 316
-3.4%
0,85
48.139 US$
|
56 316
-3.4%
|
0,85
|
48.139 US$
|
|
|
2018-12-27 |
2018-12-27 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
14 800
-0.9%
0,88
13.028 US$
|
14 800
-0.9%
|
0,88
|
13.028 US$
|
|
|
2018-12-27 |
2018-12-26 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
30 726
-1.8%
0,91
27.868 US$
|
30 726
-1.8%
|
0,91
|
27.868 US$
|
|
|
2018-12-27 |
2018-12-26 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
28 745
-1.7%
0,91
26.037 US$
|
28 745
-1.7%
|
0,91
|
26.037 US$
|
|
|
2018-12-27 |
2018-12-26 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
12 219
-0.7%
0,91
11.108 US$
|
12 219
-0.7%
|
0,91
|
11.108 US$
|
|
|
2018-12-27 |
2018-12-26 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
109 900
-5.9%
0,87
95.833 US$
|
109 900
-5.9%
|
0,87
|
95.833 US$
|
|
|
2018-12-27 |
2018-12-26 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
12 450
-0.7%
0,91
11.302 US$
|
12 450
-0.7%
|
0,91
|
11.302 US$
|
|
|
2018-12-27 |
2018-12-26 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
83 245
-4.3%
0,98
81.447 US$
|
83 245
-4.3%
|
0,98
|
81.447 US$
|
|
|
2018-12-27 |
2018-12-26 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
1 200
-0.1%
0,93
1.119 US$
|
1 200
-0.1%
|
0,93
|
1.119 US$
|
|
|
2018-12-27 |
2018-12-24 |
S
Venta
|
Broadfin Healthcare Master Fund Ltd
Gran accionista
|
400
-0.0%
0,98
392 US$
|
400
-0.0%
|
0,98
|
392 US$
|
|
|
2017-06-13 |
2017-06-12 |
B
Compra
|
Stern Donald K
|
2 500
+inf%
9,10
22.750 US$
|
2 500
+inf%
|
9,10
|
22.750 US$
|
|
|
2017-05-17 |
2017-05-15 |
B
Compra
|
Aryeh Jason
Consejero no ejecutivo
|
361
+0.1%
8,95
3.231 US$
|
361
+0.1%
|
8,95
|
3.231 US$
|
|
|
2016-09-15 |
2016-09-15 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
14 928
+0.3%
1,55
23.138 US$
|
14 928
+0.3%
|
1,55
|
23.138 US$
|
|
|
2016-09-15 |
2016-09-14 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
56 864
+1.0%
1,55
88.270 US$
|
56 864
+1.0%
|
1,55
|
88.270 US$
|
|
|
2016-09-15 |
2016-09-13 |
B
Compra
|
STONEPINE CAPITAL, L.P.
Gran accionista
|
61 704
+1.1%
1,54
95.166 US$
|
61 704
+1.1%
|
1,54
|
95.166 US$
|
|
|
2015-12-30 |
2015-12-29 |
B
Compra
|
Aryeh Jason
Consejero no ejecutivo
|
400
+0.1%
2,49
996 US$
|
400
+0.1%
|
2,49
|
996 US$
|
|
|
2015-12-30 |
2015-12-29 |
B
Compra
|
Aryeh Jason
Consejero no ejecutivo
|
18 000
+4.1%
2,50
45.000 US$
|
18 000
+4.1%
|
2,50
|
45.000 US$
|
|
|
2015-06-18 |
2015-06-16 |
B
Compra
|
Aryeh Jason
Consejero no ejecutivo
|
288 000
+inf%
3,47
999.360 US$
|
288 000
+inf%
|
3,47
|
999.360 US$
|
|
|
2015-06-17 |
2015-06-16 |
S
Venta
|
AXIAL CAPITAL MANAGEMENT, LLC
Gran accionista
|
8 865 036
-100.0%
3,47
30.771.426 US$
|
8 865 036
-100.0%
|
3,47
|
30.771.426 US$
|
|
|
2015-06-17 |
2015-06-16 |
S
Venta
|
Axial Capital Master, L.P.
Gran accionista
|
7 563 053
-100.0%
3,47
26.252.113 US$
|
7 563 053
-100.0%
|
3,47
|
26.252.113 US$
|
|
|
2014-12-23 |
2014-12-22 |
B
Compra
|
KOZARICH JOHN W
Consejero no ejecutivo
|
900
+4.3%
3,62
3.258 US$
|
900
+4.3%
|
3,62
|
3.258 US$
|
|
|
2014-12-23 |
2014-12-22 |
B
Compra
|
KOZARICH JOHN W
Consejero no ejecutivo
|
600
+2.9%
3,62
2.172 US$
|
600
+2.9%
|
3,62
|
2.172 US$
|
|
|
2014-12-23 |
2014-12-22 |
B
Compra
|
KOZARICH JOHN W
Consejero no ejecutivo
|
4 400
+27.3%
3,62
15.928 US$
|
4 400
+27.3%
|
3,62
|
15.928 US$
|
|
|
2014-12-23 |
2014-12-22 |
B
Compra
|
KOZARICH JOHN W
Consejero no ejecutivo
|
900
+5.9%
3,62
3.258 US$
|
900
+5.9%
|
3,62
|
3.258 US$
|
|
|
2014-12-23 |
2014-12-22 |
B
Compra
|
KOZARICH JOHN W
Consejero no ejecutivo
|
600
+4.1%
3,63
2.178 US$
|
600
+4.1%
|
3,63
|
2.178 US$
|
|
|
2014-12-23 |
2014-12-22 |
B
Compra
|
KOZARICH JOHN W
Consejero no ejecutivo
|
900
+6.6%
3,63
3.267 US$
|
900
+6.6%
|
3,63
|
3.267 US$
|
|
|
2014-12-23 |
2014-12-19 |
B
Compra
|
KOZARICH JOHN W
Consejero no ejecutivo
|
1 700
+14.2%
3,45
5.865 US$
|
1 700
+14.2%
|
3,45
|
5.865 US$
|
|
|
2014-12-19 |
2014-12-18 |
B
Compra
|
Meckler Jeffrey A
Consejero no ejecutivo
|
20 000
+38.5%
3,60
72.000 US$
|
20 000
+38.5%
|
3,60
|
72.000 US$
|
|
|
2014-07-15 |
2014-07-11 |
S
Venta
|
NB Public Equity K/S
Gran accionista
|
1 000 000
-13.4%
5,80
5.800.000 US$
|
1 000 000
-13.4%
|
5,80
|
5.800.000 US$
|
|
|
2013-07-02 |
2013-07-01 |
S
Venta
|
Axial Capital Master, L.P.
Gran accionista
|
288 890
-3.7%
4,39
1.268.227 US$
|
288 890
-3.7%
|
4,39
|
1.268.227 US$
|
|
|
2013-07-01 |
2013-06-28 |
B
Compra
|
Meckler Jeffrey A
Consejero no ejecutivo
|
30 000
+150.0%
4,36
130.800 US$
|
30 000
+150.0%
|
4,36
|
130.800 US$
|
|
|
2013-05-15 |
2013-05-14 |
S
Venta
|
Jagpal Sukhi
Chief Financial Officer
Oficial
|
100
-7.7%
7,96
796 US$
|
100
-7.7%
|
7,96
|
796 US$
|
|
|
2013-05-15 |
2013-05-14 |
S
Venta
|
Jagpal Sukhi
Chief Financial Officer
Oficial
|
9 900
-88.4%
7,95
78.705 US$
|
9 900
-88.4%
|
7,95
|
78.705 US$
|
|
|
2013-05-14 |
2013-05-13 |
B
Compra
|
KOZARICH JOHN W
Consejero no ejecutivo
|
10 000
+inf%
7,97
79.700 US$
|
10 000
+inf%
|
7,97
|
79.700 US$
|
|
|
2013-05-06 |
2013-05-03 |
S
Venta
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
90 000
-81.8%
7,85
706.500 US$
|
90 000
-81.8%
|
7,85
|
706.500 US$
|
|
|
2013-05-06 |
2013-05-03 |
B
Compra
|
Meckler Jeffrey A
Consejero no ejecutivo
|
20 000
+inf%
7,96
159.200 US$
|
20 000
+inf%
|
7,96
|
159.200 US$
|
|
|
2012-12-28 |
2012-12-28 |
S
Venta
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
50 000
-71.4%
7,51
375.315 US$
|
50 000
-71.4%
|
7,51
|
375.315 US$
|
|
|
2012-12-28 |
2012-12-27 |
S
Venta
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
180 000
-90.0%
7,53
1.354.734 US$
|
180 000
-90.0%
|
7,53
|
1.354.734 US$
|
|
|
2012-12-13 |
2012-12-12 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
8,02
40.100 US$
|
5 000
-20.0%
|
8,02
|
40.100 US$
|
|
|
2012-11-29 |
2012-11-28 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,88
39.400 US$
|
5 000
-20.0%
|
7,88
|
39.400 US$
|
|
|
2012-11-21 |
2012-11-20 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,81
39.050 US$
|
5 000
-20.0%
|
7,81
|
39.050 US$
|
|
|
2012-11-05 |
2012-11-01 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,52
37.600 US$
|
5 000
-20.0%
|
7,52
|
37.600 US$
|
|
|
2012-10-23 |
2012-10-22 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,72
38.600 US$
|
5 000
-20.0%
|
7,72
|
38.600 US$
|
|
|
2012-10-05 |
2012-10-05 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,72
38.600 US$
|
5 000
-20.0%
|
7,72
|
38.600 US$
|
|
|
2012-09-19 |
2012-09-18 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,57
37.850 US$
|
5 000
-20.0%
|
7,57
|
37.850 US$
|
|
|
2012-09-06 |
2012-09-05 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,55
37.750 US$
|
5 000
-20.0%
|
7,55
|
37.750 US$
|
|
|
2012-08-20 |
2012-08-20 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,67
38.350 US$
|
5 000
-20.0%
|
7,67
|
38.350 US$
|
|
|
2012-08-15 |
2012-08-13 |
S
Venta
|
LUPINI LINDA
Senior VP, HR & Org. Dev.
Oficial
|
77 007
-83.7%
7,58
583.929 US$
|
77 007
-83.7%
|
7,58
|
583.929 US$
|
|
|
2012-08-10 |
2012-08-08 |
S
Venta
|
LUPINI LINDA
Senior VP, HR & Org. Dev.
Oficial
|
22 993
-60.5%
7,85
180.495 US$
|
22 993
-60.5%
|
7,85
|
180.495 US$
|
|
|
2012-08-08 |
2012-08-08 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,92
39.600 US$
|
5 000
-20.0%
|
7,92
|
39.600 US$
|
|
|
2012-08-07 |
2012-08-03 |
S
Venta
|
Jagpal Sukhi
Interim CFO
Oficial
|
67 000
-98.2%
8,19
548.730 US$
|
67 000
-98.2%
|
8,19
|
548.730 US$
|
|
|
2012-07-25 |
2012-07-24 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
8,28
41.400 US$
|
5 000
-20.0%
|
8,28
|
41.400 US$
|
|
|
2012-07-11 |
2012-07-09 |
S
Venta
|
CLARKE C BOYD
Former Director
|
20 000
-100.0%
7,62
152.460 US$
|
20 000
-100.0%
|
7,62
|
152.460 US$
|
|
|
2012-07-11 |
2012-07-09 |
S
Venta
|
CLARKE C BOYD
Former Director
|
55 450
-100.0%
7,62
422.291 US$
|
55 450
-100.0%
|
7,62
|
422.291 US$
|
|
|
2012-07-10 |
2012-07-09 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,53
37.650 US$
|
5 000
-20.0%
|
7,53
|
37.650 US$
|
|
|
2012-06-22 |
2012-06-21 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,65
38.250 US$
|
5 000
-20.0%
|
7,65
|
38.250 US$
|
|
|
2012-06-19 |
2012-06-15 |
Por favor
Venta prevista
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 000
-20.0%
7,47
37.350 US$
|
5 000
-20.0%
|
7,47
|
37.350 US$
|
|
|
2012-05-18 |
2012-05-16 |
B
Compra
|
NB Public Equity K/S
Gran accionista
|
50 000
+0.7%
6,67
333.340 US$
|
50 000
+0.7%
|
6,67
|
333.340 US$
|
|
|
2012-05-16 |
2012-05-15 |
B
Compra
|
CLARKE C BOYD
Consejero no ejecutivo
|
2 450
+3.4%
6,56
16.072 US$
|
2 450
+3.4%
|
6,56
|
16.072 US$
|
|
|
2011-11-30 |
2011-11-29 |
S
Venta
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
20 000
-50.0%
6,73
134.522 US$
|
20 000
-50.0%
|
6,73
|
134.522 US$
|
|
|
2011-11-30 |
2011-11-29 |
S
Venta
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
4 400
-9.9%
6,85
30.120 US$
|
4 400
-9.9%
|
6,85
|
30.120 US$
|
|
|
2011-11-30 |
2011-11-28 |
S
Venta
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
5 600
-21.9%
7,03
39.361 US$
|
5 600
-21.9%
|
7,03
|
39.361 US$
|
|
|
2011-11-23 |
2011-11-23 |
B
Compra
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
1 300
+7.0%
6,78
8.813 US$
|
1 300
+7.0%
|
6,78
|
8.813 US$
|
|
|
2011-11-23 |
2011-11-23 |
B
Compra
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
2 200
+13.3%
6,77
14.897 US$
|
2 200
+13.3%
|
6,77
|
14.897 US$
|
|
|
2011-11-23 |
2011-11-23 |
B
Compra
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
1 500
+10.0%
6,76
10.143 US$
|
1 500
+10.0%
|
6,76
|
10.143 US$
|
|
|
2011-11-23 |
2011-11-22 |
B
Compra
|
Lussow Alexander R
Sr. VP, Bus. Dev. & Comm. Op.
Oficial
|
400
+2.7%
6,96
2.783 US$
|
400
+2.7%
|
6,96
|
2.783 US$
|
|