Column Group IV GP, LP

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2026-02-09	2026-02-06	Eikon Therapeutics Inc (EIKN)	B Purchase	56,127 +13.5% 443.21 US$111,780	56,127 +13.5%	443.21	US$111,780
2026-02-09	2026-02-06	Eikon Therapeutics Inc (EIKN)	B Purchase	69,727 +27.1% 305.64 US$4,605,213	69,727 +27.1%	305.64	US$4,605,213
2026-02-09	2026-02-06	Eikon Therapeutics Inc (EIKN)	B Purchase	52,271 -39.0% 264.15 US$3,033,212	52,271 -39.0%	264.15	US$3,033,212