United States Biotechnology & Medical Research

Plus Therapeutics Inc (PSTV)

Track

The most recent insider trading activity at Plus Therapeutics Inc. occurred on November 4, 2025, when the Chief Financial Officer executed a purchase of company shares. Prior to this, there were additional buy transactions recorded in August 2025. No insider trading activity has been reported within the last three months.
Ticker: PSTV Exchange: NAS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Plus Therapeutics Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Trades
Buy 4 Nov 2025
Value US$3,980,364.51 | Price 353.15 | Shares 25,689 (+27.1%)
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2025-11-05 2025-11-04 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
25,689 +27.1%
353.15
US$3,980,365 		25,689 +27.1% 353.15 US$3,980,365
2025-08-25 2025-08-22 B Purchase
2.1
Lenk Robert P
Non-Executive Director
67,681 -46.0%
351.22
US$3,929,310 		67,681 -46.0% 351.22 US$3,929,310
2025-05-07 2025-05-15 PrS Proposed sale
3.1
Petersen Greg

Director

Non-Executive Director
67,356
268.44
US$3,194,986 		67,356 268.44 US$3,194,986
2024-09-17 2024-09-13 B Purchase
4.2
Hawkins Richard J
Non-Executive Director
4,000 +35.8%
1.50
US$5,996 		4,000 +35.8% 1.50 US$5,996
2024-09-16 2024-09-12 B Purchase
4.2
Hawkins Richard J
Non-Executive Director
6,285 +128.2%
1.35
US$8,512 		6,285 +128.2% 1.35 US$8,512
2024-09-13 2024-09-11 B Purchase
2.8
Clowes Howard
Non-Executive Director
5,000 +23.3%
1.34
US$6,681 		5,000 +23.3% 1.34 US$6,681
2024-09-13 2024-09-11 B Purchase
3.1
Petersen Greg
Non-Executive Director
12,500 +34.3%
1.35
US$16,875 		12,500 +34.3% 1.35 US$16,875
2024-09-11 2024-09-10 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
4,098 +71.7%
1.27
US$5,204 		4,098 +71.7% 1.27 US$5,204
2024-09-11 2024-09-10 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
8,000 +64.4%
1.23
US$9,839 		8,000 +64.4% 1.23 US$9,839
2024-05-10 2024-05-08 B Purchase
2.1
Lenk Robert P
Non-Executive Director
4,167 +16.6%
2.04
US$8,501 		4,167 +16.6% 2.04 US$8,501
2024-05-10 2024-05-08 B Purchase
2.1
Lenk Robert P
Non-Executive Director
4,167 +16.6%
2.04
US$8,501 		4,167 +16.6% 2.04 US$8,501
2024-05-10 2024-05-08 B Purchase
2.8
Clowes Howard
Non-Executive Director
9,804 +83.8%
2.04
US$20,000 		9,804 +83.8% 2.04 US$20,000
2024-05-10 2024-05-08 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
12,255 +7208.8%
2.04
US$25,000 		12,255 +7208.8% 2.04 US$25,000
2024-05-10 2024-05-08 B Purchase
3.1
Petersen Greg
Non-Executive Director
12,255 +50.7%
2.04
US$25,000 		12,255 +50.7% 2.04 US$25,000
2024-05-10 2024-05-08 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
4,902 +601.5%
2.04
US$10,000 		4,902 +601.5% 2.04 US$10,000
2024-05-10 2024-05-08 B Purchase
4.2
Hawkins Richard J
Non-Executive Director
4,902 +490200.0%
2.04
US$10,000 		4,902 +490200.0% 2.04 US$10,000
2023-12-15 2023-11-20 S Sale
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,068 -92.4%
1.96
US$4,053 		2,068 -92.4% 1.96 US$4,053
2023-11-17 2023-11-16 B Purchase
2.1
Lenk Robert P
Non-Executive Director
1,000 +4.1%
1.95
US$1,950 		1,000 +4.1% 1.95 US$1,950
2023-11-17 2023-11-15 B Purchase
2.1
Lenk Robert P
Non-Executive Director
1,000 +4.3%
1.77
US$1,770 		1,000 +4.3% 1.77 US$1,770
2023-11-15 2023-11-13 B Purchase
2.1
Lenk Robert P
Non-Executive Director
4,000 +20.9%
1.43
US$5,720 		4,000 +20.9% 1.43 US$5,720
2023-11-15 2023-11-10 B Purchase
2.1
Lenk Robert P
Non-Executive Director
2,000 +11.7%
1.45
US$2,900 		2,000 +11.7% 1.45 US$2,900
2023-11-13 2023-11-09 B Purchase
2.1
Lenk Robert P
Non-Executive Director
4,199 +32.4%
1.59
US$6,676 		4,199 +32.4% 1.59 US$6,676
2023-11-13 2023-11-08 B Purchase
2.1
Lenk Robert P
Non-Executive Director
5,000 +62.8%
1.65
US$8,250 		5,000 +62.8% 1.65 US$8,250
2023-11-08 2023-11-07 B Purchase
2.1
Lenk Robert P
Non-Executive Director
6,000 +306.0%
1.64
US$9,840 		6,000 +306.0% 1.64 US$9,840
2023-11-08 2023-11-06 B Purchase
2.1
Lenk Robert P
Non-Executive Director
1,395 +246.5%
1.50
US$2,092 		1,395 +246.5% 1.50 US$2,092
2023-09-15 2023-09-13 B Purchase
2.8
Clowes Howard
Non-Executive Director
6,993 +148.8%
1.43
US$10,022 		6,993 +148.8% 1.43 US$10,022
2023-09-12 2023-09-11 B Purchase
3.1
Petersen Greg
Non-Executive Director
20,000 +480.1%
1.70
US$34,062 		20,000 +480.1% 1.70 US$34,062
2023-06-08 2023-06-06 B Purchase
2.8
Clowes Howard
Non-Executive Director
1,000 +27.0%
3.98
US$3,980 		1,000 +27.0% 3.98 US$3,980
2023-05-04 2023-05-03 B Purchase
2.8
Clowes Howard
Non-Executive Director
2,500 +208.3%
3.64
US$9,102 		2,500 +208.3% 3.64 US$9,102
2023-03-06 2023-03-03 B Purchase
4.2
Hawkins Richard J
Non-Executive Director
1 +inf%
1,000.00
US$1,000 		1 +inf% 1,000.00 US$1,000
2023-01-04 2022-12-30 S Sale
2.1
Lenk Robert P
Non-Executive Director
1,500 -15.0%
0.31
US$472 		1,500 -15.0% 0.31 US$472
2022-06-16 2022-06-15 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
5,000 +17.5%
0.65
US$3,240 		5,000 +17.5% 0.65 US$3,240
2022-06-06 2022-06-02 B Purchase
2.8
Clowes Howard
Non-Executive Director
15,000 +500.0%
0.57
US$8,589 		15,000 +500.0% 0.57 US$8,589
2022-05-19 2022-05-17 B Purchase
3.1
Petersen Greg
Non-Executive Director
30,000 +92.3%
0.55
US$16,500 		30,000 +92.3% 0.55 US$16,500
2022-04-28 2022-04-26 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,500 +9.6%
0.68
US$1,710 		2,500 +9.6% 0.68 US$1,710
2022-04-27 2022-04-26 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
5,000 +23.7%
0.69
US$3,450 		5,000 +23.7% 0.69 US$3,450
2022-04-27 2022-04-26 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
3,000 +32.5%
0.67
US$2,016 		3,000 +32.5% 0.67 US$2,016
2022-03-03 2022-03-01 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
2,000 +27.7%
1.10
US$2,200 		2,000 +27.7% 1.10 US$2,200
2021-11-04 2021-11-02 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
1,000 +16.1%
1.86
US$1,864 		1,000 +16.1% 1.86 US$1,864
2021-10-28 2021-10-27 B Purchase
3.1
Petersen Greg
Non-Executive Director
12,500 +62.5%
1.72
US$21,500 		12,500 +62.5% 1.72 US$21,500
2021-10-27 2021-10-26 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,500 +13.5%
1.66
US$4,150 		2,500 +13.5% 1.66 US$4,150
2021-10-27 2021-10-26 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
2,000 +47.3%
1.67
US$3,339 		2,000 +47.3% 1.67 US$3,339
2021-05-03 2021-04-30 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,183 +13.3%
2.28
US$4,970 		2,183 +13.3% 2.28 US$4,970
2021-03-05 2021-03-04 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,500 +18.0%
2.50
US$6,250 		2,500 +18.0% 2.50 US$6,250
2021-03-04 2021-03-03 B Purchase
2.8
Clowes Howard
Non-Executive Director
3,000 +inf%
2.42
US$7,260 		3,000 +inf% 2.42 US$7,260
2020-12-14 2020-12-10 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,500 +22.0%
1.99
US$4,975 		2,500 +22.0% 1.99 US$4,975
2020-12-02 2020-11-30 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Officer
2,200 +24.0%
2.14
US$4,708 		2,200 +24.0% 2.14 US$4,708
2020-08-26 2020-08-25 B Purchase
2.1
Lenk Robert P
Non-Executive Director
3,000 +inf%
2.49
US$7,465 		3,000 +inf% 2.49 US$7,465
2020-08-14 2020-08-13 B Purchase
3.1
Petersen Greg
Non-Executive Director
10,000 +100.0%
2.80
US$28,000 		10,000 +100.0% 2.80 US$28,000
2020-08-13 2020-08-12 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Officer
4,000 +77.4%
2.58
US$10,318 		4,000 +77.4% 2.58 US$10,318
2020-08-13 2020-08-12 B Purchase
3.1
Petersen Greg
Non-Executive Director
10,000 +inf%
2.52
US$25,200 		10,000 +inf% 2.52 US$25,200
2020-06-23 2020-06-22 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Officer
5,000 +2994.0%
2.10
US$10,500 		5,000 +2994.0% 2.10 US$10,500
2018-02-15 2018-02-14 S Sale PostFinance AG Large shareholder
473,831 -9.4%
0.34
US$161,008 		473,831 -9.4% 0.34 US$161,008
2018-02-14 2018-02-13 S Sale PostFinance AG Large shareholder
101,710 -2.0%
0.31
US$31,652 		101,710 -2.0% 0.31 US$31,652
2018-02-14 2018-02-12 S Sale PostFinance AG Large shareholder
185,272 -3.5%
0.31
US$58,324 		185,272 -3.5% 0.31 US$58,324
2018-02-12 2018-02-09 S Sale PostFinance AG Large shareholder
7,552 -0.1%
0.34
US$2,568 		7,552 -0.1% 0.34 US$2,568
2018-02-12 2018-02-08 S Sale PostFinance AG Large shareholder
228,603 -4.1%
0.34
US$78,434 		228,603 -4.1% 0.34 US$78,434
2018-01-11 2018-01-11 S Sale Swissquote Bank SA
20,000 -0.4%
0.34
US$6,800 		20,000 -0.4% 0.34 US$6,800
2018-01-11 2018-01-11 S Sale Swissquote Bank SA
12,630 -0.2%
0.34
US$4,294 		12,630 -0.2% 0.34 US$4,294
2018-01-11 2018-01-11 S Sale Swissquote Bank SA
20,000 -0.4%
0.34
US$6,812 		20,000 -0.4% 0.34 US$6,812
2018-01-11 2018-01-11 S Sale Swissquote Bank SA
20,000 -0.4%
0.34
US$6,810 		20,000 -0.4% 0.34 US$6,810
2018-01-11 2018-01-10 S Sale Swissquote Bank SA
15,796 -0.3%
0.38
US$6,007 		15,796 -0.3% 0.38 US$6,007
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.39
US$7,804 		20,000 -0.4% 0.39 US$7,804
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.40
US$7,928 		20,000 -0.4% 0.40 US$7,928
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.38
US$7,600 		20,000 -0.4% 0.38 US$7,600
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.38
US$7,600 		20,000 -0.4% 0.38 US$7,600
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.37
US$7,400 		20,000 -0.4% 0.37 US$7,400
2016-08-11 2016-08-10 B Purchase HARRIS JOHN DAVID

VP and GM Cell Therapy

Officer
2,500 +55.6%
2.03
US$5,075 		2,500 +55.6% 2.03 US$5,075
2016-06-15 2016-06-14 B Purchase Naughton Gail K Non-Executive Director
1,000 +71.4%
2.10
US$2,100 		1,000 +71.4% 2.10 US$2,100
2016-06-15 2016-06-14 B Purchase RICKEY DAVID Non-Executive Director
5,000 +10.0%
2.10
US$10,500 		5,000 +10.0% 2.10 US$10,500
2016-05-16 2016-05-13 B Purchase HARRIS JOHN DAVID

VP and GM Cell Therapy

Officer
2,000 +inf%
2.71
US$5,420 		2,000 +inf% 2.71 US$5,420
2016-03-09 2016-03-09 B Purchase RICKEY DAVID Non-Executive Director
100,000 +15.3%
0.19
US$18,860 		100,000 +15.3% 0.19 US$18,860
2016-03-09 2016-03-09 B Purchase RICKEY DAVID Non-Executive Director
50,000 +22.7%
0.19
US$9,430 		50,000 +22.7% 0.19 US$9,430
2015-09-08 2015-09-03 B Purchase Thompson Tommy G Non-Executive Director
25,449 +43.8%
0.37
US$9,531 		25,449 +43.8% 0.37 US$9,531
2015-09-03 2015-09-02 B Purchase HAYDEN JEREMY B.

General Counsel & VP of BD

Officer
8,200 +45.6%
0.36
US$2,911 		8,200 +45.6% 0.36 US$2,911
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