|
March 3, 2023 |
March 1, 2023 |
PS
Planned sale
|
Henderson Molly
CFO and CBO
Officer
|
2,032
-2.6%
8.53
17,335
USD
|
2,032
-2.6%
|
8.53
|
17,335
USD
|
|
|
March 3, 2023 |
March 1, 2023 |
PS
Planned sale
|
Curran Terrie
President and Chief Executive
Executive Director
|
1,436
-0.8%
8.54
12,265
USD
|
1,436
-0.8%
|
8.54
|
12,265
USD
|
|
|
Feb. 14, 2023 |
Feb. 13, 2023 |
B
Purchase
|
Parikh Asit
Non-Executive Director
|
5,000
+28.6%
7.73
38,660
USD
|
5,000
+28.6%
|
7.73
|
38,660
USD
|
|
|
Jan. 20, 2023 |
Jan. 20, 2023 |
S
Sale
|
Curran Terrie
President and Chief Executive
Executive Director
|
5,821
-3.2%
8.20
47,729
USD
|
5,821
-3.2%
|
8.20
|
47,729
USD
|
|
|
Jan. 12, 2023 |
Jan. 12, 2023 |
B
Purchase
|
Parikh Asit
Non-Executive Director
|
5,000
+40.0%
7.00
35,000
USD
|
5,000
+40.0%
|
7.00
|
35,000
USD
|
|
|
Nov. 23, 2022 |
Nov. 21, 2022 |
S
Sale
|
Henderson Molly
CFO and CBO
Officer
|
2,159
-4.7%
9.60
20,726
USD
|
2,159
-4.7%
|
9.60
|
20,726
USD
|
|
|
Nov. 23, 2022 |
Nov. 21, 2022 |
S
Sale
|
Curran Terrie
President and Chief Executive
Executive Director
|
1,526
-1.8%
9.60
14,650
USD
|
1,526
-1.8%
|
9.60
|
14,650
USD
|
|
|
May 16, 2022 |
May 16, 2022 |
B
Purchase
|
Nabulsi Azmi
Chief Operating Officer
Officer
|
20,000
+2.6%
8.16
163,288
USD
|
20,000
+2.6%
|
8.16
|
163,288
USD
|
|
|
May 16, 2022 |
May 13, 2022 |
B
Purchase
|
Curran Terrie
President and Chief Executive
Executive Director
|
20,500
+46.5%
7.41
151,835
USD
|
20,500
+46.5%
|
7.41
|
151,835
USD
|
|
|
May 16, 2022 |
May 12, 2022 |
B
Purchase
|
Parikh Asit
Non-Executive Director
|
12,500
+inf%
8.00
100,000
USD
|
12,500
+inf%
|
8.00
|
100,000
USD
|
|
|
March 16, 2022 |
March 14, 2022 |
S
Sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
18
-0.0%
19.00
342
USD
|
18
-0.0%
|
19.00
|
342
USD
|
|
|
Nov. 8, 2021 |
Nov. 4, 2021 |
S
Sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
1,000,000
-90.9%
20.85
20,850,000
USD
|
1,000,000
-90.9%
|
20.85
|
20,850,000
USD
|
|
|
Nov. 8, 2021 |
Nov. 4, 2021 |
S
Sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
1
-0.0%
19.00
19
USD
|
1
-0.0%
|
19.00
|
19
USD
|
|
|
Oct. 8, 2021 |
Oct. 8, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
2,529
-0.2%
32.05
81,052
USD
|
2,529
-0.2%
|
32.05
|
81,052
USD
|
|
|
Oct. 8, 2021 |
Oct. 7, 2021 |
PS
Planned sale
|
Socks David A
Non-Executive Director
|
15,471
-1.3%
32.66
505,343
USD
|
15,471
-1.3%
|
32.66
|
505,343
USD
|
|
|
June 29, 2021 |
June 29, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
13,960
-1.1%
34.00
474,657
USD
|
13,960
-1.1%
|
34.00
|
474,657
USD
|
|
|
June 29, 2021 |
June 28, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
156
-0.0%
35.09
5,474
USD
|
156
-0.0%
|
35.09
|
5,474
USD
|
|
|
June 29, 2021 |
June 28, 2021 |
PS
Planned sale
|
Socks David A
Non-Executive Director
|
25,884
-2.0%
34.07
881,811
USD
|
25,884
-2.0%
|
34.07
|
881,811
USD
|
|
|
June 29, 2021 |
June 28, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
370
-0.0%
35.08
12,980
USD
|
370
-0.0%
|
35.08
|
12,980
USD
|
|
|
June 29, 2021 |
June 25, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
1,250
-0.1%
36.07
45,088
USD
|
1,250
-0.1%
|
36.07
|
45,088
USD
|
|
|
June 29, 2021 |
June 25, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
22,881
-2.5%
35.46
811,360
USD
|
22,881
-2.5%
|
35.46
|
811,360
USD
|
|
|
June 25, 2021 |
June 24, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
10,848
-1.2%
35.14
381,199
USD
|
10,848
-1.2%
|
35.14
|
381,199
USD
|
|
|
June 25, 2021 |
June 23, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
200
-0.0%
35.00
7,000
USD
|
200
-0.0%
|
35.00
|
7,000
USD
|
|
|
June 23, 2021 |
June 22, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
100
-0.0%
35.00
3,500
USD
|
100
-0.0%
|
35.00
|
3,500
USD
|
|
|
June 23, 2021 |
June 21, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
9,294
-1.0%
35.31
328,171
USD
|
9,294
-1.0%
|
35.31
|
328,171
USD
|
|
|
June 21, 2021 |
June 18, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
5,398
-0.6%
35.13
189,632
USD
|
5,398
-0.6%
|
35.13
|
189,632
USD
|
|
|
June 21, 2021 |
June 17, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
3,305
-0.4%
35.08
115,939
USD
|
3,305
-0.4%
|
35.08
|
115,939
USD
|
|
|
June 16, 2021 |
June 14, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
2,826
-0.3%
35.06
99,080
USD
|
2,826
-0.3%
|
35.06
|
99,080
USD
|
|
|
June 11, 2021 |
June 10, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
2,102
-0.2%
35.14
73,864
USD
|
2,102
-0.2%
|
35.14
|
73,864
USD
|
|
|
June 11, 2021 |
June 9, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
1,191
-0.1%
35.28
42,018
USD
|
1,191
-0.1%
|
35.28
|
42,018
USD
|
|
|
June 9, 2021 |
June 8, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
100
-0.0%
35.00
3,500
USD
|
100
-0.0%
|
35.00
|
3,500
USD
|
|
|
June 9, 2021 |
June 7, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
2,264
-0.2%
35.05
79,353
USD
|
2,264
-0.2%
|
35.05
|
79,353
USD
|
|
|
June 4, 2021 |
June 2, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
4,300
-0.5%
35.18
151,274
USD
|
4,300
-0.5%
|
35.18
|
151,274
USD
|
|
|
June 2, 2021 |
June 1, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
3,967
-0.4%
36.20
143,605
USD
|
3,967
-0.4%
|
36.20
|
143,605
USD
|
|
|
June 2, 2021 |
June 1, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
7,244
-0.8%
35.55
257,524
USD
|
7,244
-0.8%
|
35.55
|
257,524
USD
|
|
|
June 2, 2021 |
May 28, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
2,104
-0.2%
37.55
79,005
USD
|
2,104
-0.2%
|
37.55
|
79,005
USD
|
|
|
June 2, 2021 |
May 28, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
2,668
-0.3%
36.40
97,115
USD
|
2,668
-0.3%
|
36.40
|
97,115
USD
|
|
|
June 2, 2021 |
May 28, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
4,133
-0.4%
35.37
146,184
USD
|
4,133
-0.4%
|
35.37
|
146,184
USD
|
|
|
May 26, 2021 |
May 25, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
548
-0.1%
36.59
20,051
USD
|
548
-0.1%
|
36.59
|
20,051
USD
|
|
|
May 26, 2021 |
May 25, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
10,399
-1.0%
36.16
376,028
USD
|
10,399
-1.0%
|
36.16
|
376,028
USD
|
|
|
May 26, 2021 |
May 24, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
1,683
-0.2%
36.10
60,756
USD
|
1,683
-0.2%
|
36.10
|
60,756
USD
|
|
|
May 26, 2021 |
May 24, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
8,911
-0.9%
35.58
317,053
USD
|
8,911
-0.9%
|
35.58
|
317,053
USD
|
|
|
May 24, 2021 |
May 21, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
11,648
-1.1%
35.74
416,300
USD
|
11,648
-1.1%
|
35.74
|
416,300
USD
|
|
|
May 24, 2021 |
May 20, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
7,098
-0.7%
35.10
249,140
USD
|
7,098
-0.7%
|
35.10
|
249,140
USD
|
|
|
May 18, 2021 |
May 14, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
100
-0.0%
35.00
3,500
USD
|
100
-0.0%
|
35.00
|
3,500
USD
|
|
|
May 14, 2021 |
May 13, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
100
-0.0%
35.33
3,533
USD
|
100
-0.0%
|
35.33
|
3,533
USD
|
|
|
May 14, 2021 |
May 12, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
905
-0.1%
36.06
32,634
USD
|
905
-0.1%
|
36.06
|
32,634
USD
|
|
|
May 14, 2021 |
May 12, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
10,871
-1.0%
35.39
384,725
USD
|
10,871
-1.0%
|
35.39
|
384,725
USD
|
|
|
May 11, 2021 |
May 7, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
1,011
-0.1%
35.03
35,415
USD
|
1,011
-0.1%
|
35.03
|
35,415
USD
|
|
|
May 7, 2021 |
May 6, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
202
-0.0%
35.01
7,072
USD
|
202
-0.0%
|
35.01
|
7,072
USD
|
|
|
May 7, 2021 |
May 5, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
6,936
-0.7%
35.14
243,731
USD
|
6,936
-0.7%
|
35.14
|
243,731
USD
|
|
|
May 5, 2021 |
May 4, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
100
-0.0%
38.53
3,853
USD
|
100
-0.0%
|
38.53
|
3,853
USD
|
|
|
May 5, 2021 |
May 4, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
3,500
-0.3%
37.47
131,145
USD
|
3,500
-0.3%
|
37.47
|
131,145
USD
|
|
|
May 5, 2021 |
May 4, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
4,690
-0.4%
36.21
169,825
USD
|
4,690
-0.4%
|
36.21
|
169,825
USD
|
|
|
May 5, 2021 |
May 4, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
11,070
-1.0%
35.50
392,985
USD
|
11,070
-1.0%
|
35.50
|
392,985
USD
|
|
|
May 4, 2021 |
May 4, 2021 |
S
Sale
|
Nabulsi Azmi
Chief Operating Officer
Officer
|
1,089
-0.1%
37.86
41,231
USD
|
1,089
-0.1%
|
37.86
|
41,231
USD
|
|
|
May 4, 2021 |
May 4, 2021 |
S
Sale
|
Nabulsi Azmi
Chief Operating Officer
Officer
|
1,400
-0.2%
37.09
51,921
USD
|
1,400
-0.2%
|
37.09
|
51,921
USD
|
|
|
May 4, 2021 |
May 4, 2021 |
S
Sale
|
Nabulsi Azmi
Chief Operating Officer
Officer
|
1,968
-0.3%
36.15
71,150
USD
|
1,968
-0.3%
|
36.15
|
71,150
USD
|
|
|
May 5, 2021 |
May 3, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
203
-0.0%
39.06
7,929
USD
|
203
-0.0%
|
39.06
|
7,929
USD
|
|
|
May 5, 2021 |
May 3, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
11,272
-1.0%
38.45
433,408
USD
|
11,272
-1.0%
|
38.45
|
433,408
USD
|
|
|
May 5, 2021 |
May 3, 2021 |
PS
Planned sale
|
TAKEDA PHARMACEUTICAL CO LTD
Major owner
|
3,157
-0.3%
37.60
118,703
USD
|
3,157
-0.3%
|
37.60
|
118,703
USD
|
|
|
May 4, 2021 |
May 3, 2021 |
S
Sale
|
Nabulsi Azmi
Chief Operating Officer
Officer
|
5,753
-0.7%
38.59
221,994
USD
|
5,753
-0.7%
|
38.59
|
221,994
USD
|
|
|
May 4, 2021 |
May 3, 2021 |
PS
Planned sale
|
Nabulsi Azmi
Chief Operating Officer
Officer
|
4,290
-0.5%
37.85
162,360
USD
|
4,290
-0.5%
|
37.85
|
162,360
USD
|
|
|
April 7, 2021 |
April 6, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
6,795
-0.5%
38.03
258,415
USD
|
6,795
-0.5%
|
38.03
|
258,415
USD
|
|
|
April 7, 2021 |
April 6, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
6,328
-0.5%
37.37
236,501
USD
|
6,328
-0.5%
|
37.37
|
236,501
USD
|
|
|
April 7, 2021 |
April 6, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
3,359
-0.2%
35.97
120,823
USD
|
3,359
-0.2%
|
35.97
|
120,823
USD
|
|
|
April 7, 2021 |
April 6, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
1,400
-0.1%
34.96
48,945
USD
|
1,400
-0.1%
|
34.96
|
48,945
USD
|
|
|
April 7, 2021 |
April 5, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
1,730
-0.1%
37.15
64,275
USD
|
1,730
-0.1%
|
37.15
|
64,275
USD
|
|
|
April 7, 2021 |
April 5, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
7,769
-0.6%
36.40
282,793
USD
|
7,769
-0.6%
|
36.40
|
282,793
USD
|
|
|
April 7, 2021 |
April 5, 2021 |
PS
Planned sale
|
Socks David A
Non-Executive Director
|
12,619
-0.9%
35.69
450,337
USD
|
12,619
-0.9%
|
35.69
|
450,337
USD
|
|
|
March 23, 2021 |
March 22, 2021 |
S
Sale
|
Curran Terrie
President and Chief Executive
Executive Director
|
1,140
-100.0%
44.08
50,256
USD
|
1,140
-100.0%
|
44.08
|
50,256
USD
|
|
|
March 23, 2021 |
March 22, 2021 |
PS
Planned sale
|
Curran Terrie
President and Chief Executive
Executive Director
|
10,373
-90.1%
43.24
448,495
USD
|
10,373
-90.1%
|
43.24
|
448,495
USD
|
|
|
March 12, 2021 |
March 12, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
500
-0.0%
46.67
23,335
USD
|
500
-0.0%
|
46.67
|
23,335
USD
|
|
|
March 15, 2021 |
March 11, 2021 |
S
Sale
|
RA CAPITAL MANAGEMENT, L.P.
Major owner
|
710,000
-18.6%
43.75
31,062,500
USD
|
710,000
-18.6%
|
43.75
|
31,062,500
USD
|
|
|
March 12, 2021 |
March 11, 2021 |
S
Sale
|
Socks David A
Non-Executive Director
|
731
-0.1%
47.54
34,749
USD
|
731
-0.1%
|
47.54
|
34,749
USD
|
|
