|
2015-08-24 |
2015-08-21 |
V
Vente
|
Creech Todd A
Former Chief Financial Officer
|
83 901
+1.6%
308,78
2 921 665 $US
|
83 901
+1.6%
|
308,78
|
2 921 665 $US
|
|
|
2015-08-24 |
2015-08-20 |
V
Vente
|
Creech Todd A
Former Chief Financial Officer
|
24 229
+48.9%
126,94
3 889 218 $US
|
24 229
+48.9%
|
126,94
|
3 889 218 $US
|
|
|
2015-06-09 |
2015-06-08 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
48 311
-28.8%
352,56
4 548 587 $US
|
48 311
-28.8%
|
352,56
|
4 548 587 $US
|
|
|
2015-06-09 |
2015-06-05 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
164 227
-5.8%
57,88
9 505 459 $US
|
164 227
-5.8%
|
57,88
|
9 505 459 $US
|
|
|
2015-06-05 |
2015-06-04 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
48 913
-1.7%
57,71
2 822 769 $US
|
48 913
-1.7%
|
57,71
|
2 822 769 $US
|
|
|
2015-06-05 |
2015-06-04 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
39 495
-1.4%
57,21
2 259 509 $US
|
39 495
-1.4%
|
57,21
|
2 259 509 $US
|
|
|
2015-06-05 |
2015-06-03 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
23 189
-0.8%
56,60
1 312 497 $US
|
23 189
-0.8%
|
56,60
|
1 312 497 $US
|
|
|
2015-06-02 |
2015-06-02 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
84 342
-2.8%
56,77
4 788 095 $US
|
84 342
-2.8%
|
56,77
|
4 788 095 $US
|
|
|
2015-06-02 |
2015-06-01 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
72 520
-2.3%
58,00
4 206 160 $US
|
72 520
-2.3%
|
58,00
|
4 206 160 $US
|
|
|
2015-06-02 |
2015-05-29 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
14 696
-0.5%
59,69
877 204 $US
|
14 696
-0.5%
|
59,69
|
877 204 $US
|
|
|
2015-06-02 |
2015-05-29 |
V
Vente
|
Alta Partners VIII, L.P.
Actionnaire important
|
124 865
-3.9%
58,63
7 320 835 $US
|
124 865
-3.9%
|
58,63
|
7 320 835 $US
|
|
|
2014-12-17 |
2014-12-15 |
V
Vente
|
3x5 Special Opportunity Fund, L.P.
Actionnaire important
|
79 444
-39.2%
47,09
3 741 336 $US
|
79 444
-39.2%
|
47,09
|
3 741 336 $US
|
|
|
2014-06-25 |
2014-06-23 |
A
Achat
|
Alta Partners VIII, L.P.
Actionnaire important
|
200 000
+6.6%
18,00
3 600 000 $US
|
200 000
+6.6%
|
18,00
|
3 600 000 $US
|
|
|
2014-06-25 |
2014-06-23 |
A
Achat
|
NOHRA GUY P
Administrateur non-exécutif
|
200 000
+6.6%
18,00
3 600 000 $US
|
200 000
+6.6%
|
18,00
|
3 600 000 $US
|
|
|
2014-06-25 |
2014-06-23 |
A
Achat
|
OSTRO MARC
Administrateur non-exécutif
Actionnaire important
|
160 000
+6.6%
18,00
2 880 000 $US
|
160 000
+6.6%
|
18,00
|
2 880 000 $US
|
|
|
2014-06-25 |
2014-06-23 |
A
Achat
|
DEVON PARK BIOVENTURES LP
Actionnaire important
|
160 000
+6.6%
18,00
2 880 000 $US
|
160 000
+6.6%
|
18,00
|
2 880 000 $US
|
|
|
2014-06-24 |
2014-06-23 |
A
Achat
|
Novo A/S
See Remarks
Actionnaire important
|
275 000
+54.3%
18,00
4 950 000 $US
|
275 000
+54.3%
|
18,00
|
4 950 000 $US
|
|