|
2018-11-28 |
2018-11-27 |
A
Achat
|
Gurnet Holding Co
Actionnaire important
|
75 154
-20.0%
167,69
3 570 804 $US
|
75 154
-20.0%
|
167,69
|
3 570 804 $US
|
|
|
2018-11-28 |
2018-11-27 |
A
Achat
|
Gurnet Holding Co
Actionnaire important
|
43 181
-10.4%
93,11
1 212 741 $US
|
43 181
-10.4%
|
93,11
|
1 212 741 $US
|
|
|
2018-10-15 |
2018-10-12 |
V
Vente
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
22 220
-2.9%
427,78
3 322 340 $US
|
22 220
-2.9%
|
427,78
|
3 322 340 $US
|
|
|
2018-10-15 |
2018-10-12 |
V
Vente
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
500 000
-9.0%
12,51
6 255 000 $US
|
500 000
-9.0%
|
12,51
|
6 255 000 $US
|
|
|
2018-10-15 |
2018-10-11 |
V
Vente
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
500 000
-8.2%
12,50
6 250 000 $US
|
500 000
-8.2%
|
12,50
|
6 250 000 $US
|
|
|
2018-10-15 |
2018-10-11 |
V
Vente
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
282 447
-4.4%
12,51
3 533 412 $US
|
282 447
-4.4%
|
12,51
|
3 533 412 $US
|
|
|
2018-08-17 |
2018-08-17 |
V
Vente
|
Sweemer Timothy D
Chief Accounting Officer
Dirigeant
|
346
-1.0%
9,01
3 117 $US
|
346
-1.0%
|
9,01
|
3 117 $US
|
|
|
2018-08-17 |
2018-08-17 |
V
Vente
|
Singh Parminder
CTO & Vice President, R&D
Dirigeant
|
3 133
-16.5%
9,01
28 224 $US
|
3 133
-16.5%
|
9,01
|
28 224 $US
|
|
|
2018-08-17 |
2018-08-17 |
V
Vente
|
BREUIL ROBERT S
Chief Financial Officer
Dirigeant
|
972
-6.3%
9,01
8 756 $US
|
972
-6.3%
|
9,01
|
8 756 $US
|
|
|
2018-08-17 |
2018-08-17 |
V
Vente
|
Sarret Joseph J.
Chief Business Officer
Dirigeant
|
3 565
-18.0%
9,01
32 116 $US
|
3 565
-18.0%
|
9,01
|
32 116 $US
|
|
|
2018-08-17 |
2018-08-17 |
PlS
Vente planifiée
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
34 320
-12.2%
8,96
307 586 $US
|
34 320
-12.2%
|
8,96
|
307 586 $US
|
|
|
2018-08-17 |
2018-08-17 |
V
Vente
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
2 701
-0.9%
9,01
24 332 $US
|
2 701
-0.9%
|
9,01
|
24 332 $US
|
|
|
2018-08-17 |
2018-08-16 |
PlS
Vente planifiée
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
39 320
-12.4%
8,66
340 606 $US
|
39 320
-12.4%
|
8,66
|
340 606 $US
|
|
|
2018-08-17 |
2018-08-15 |
PlS
Vente planifiée
|
Thomas Robert
Administrateur non-exécutif
|
35 608
-100.0%
8,86
315 476 $US
|
35 608
-100.0%
|
8,86
|
315 476 $US
|
|
|
2018-01-18 |
2018-01-18 |
A
Achat
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
310 000
+5.1%
12,80
3 968 000 $US
|
310 000
+5.1%
|
12,80
|
3 968 000 $US
|
|
|
2018-01-18 |
2018-01-17 |
A
Achat
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
149 650
+2.5%
12,24
1 831 716 $US
|
149 650
+2.5%
|
12,24
|
1 831 716 $US
|
|
|
2018-01-18 |
2018-01-16 |
A
Achat
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
50 350
+0.9%
11,83
595 640 $US
|
50 350
+0.9%
|
11,83
|
595 640 $US
|
|
|
2017-11-17 |
2017-11-17 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
25 000
-0.7%
10,95
273 750 $US
|
25 000
-0.7%
|
10,95
|
273 750 $US
|
|
|
2017-11-17 |
2017-11-17 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
9 255
-0.3%
10,96
101 435 $US
|
9 255
-0.3%
|
10,96
|
101 435 $US
|
|
|
2017-11-17 |
2017-11-17 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
100 000
-2.7%
10,95
1 095 000 $US
|
100 000
-2.7%
|
10,95
|
1 095 000 $US
|
|
|
2017-11-17 |
2017-11-17 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
65 345
-1.7%
11,01
719 448 $US
|
65 345
-1.7%
|
11,01
|
719 448 $US
|
|
|
2017-11-17 |
2017-11-16 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
400
-0.0%
10,97
4 388 $US
|
400
-0.0%
|
10,97
|
4 388 $US
|
|
|
2017-11-17 |
2017-11-16 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
25 000
-0.7%
10,88
272 000 $US
|
25 000
-0.7%
|
10,88
|
272 000 $US
|
|
|
2017-11-17 |
2017-11-16 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
25 000
-0.7%
10,85
271 250 $US
|
25 000
-0.7%
|
10,85
|
271 250 $US
|
|
|
2017-11-17 |
2017-11-16 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
250 000
-6.1%
10,97
2 742 500 $US
|
250 000
-6.1%
|
10,97
|
2 742 500 $US
|
|
|
2017-11-03 |
2017-11-02 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
150 000
-3.6%
11,05
1 657 500 $US
|
150 000
-3.6%
|
11,05
|
1 657 500 $US
|
|
|
2017-10-06 |
2017-10-04 |
V
Vente
|
Broadfin Healthcare Master Fund Ltd
Actionnaire important
|
218 100
-4.9%
11,01
2 401 107 $US
|
218 100
-4.9%
|
11,01
|
2 401 107 $US
|
|
|
2017-08-23 |
2017-08-22 |
V
Vente
|
Singh Parminder
CTO & Vice President, R&D
|
22 822
-74.2%
7,61
173 561 $US
|
22 822
-74.2%
|
7,61
|
173 561 $US
|
|
|
2017-08-23 |
2017-08-21 |
V
Vente
|
Singh Parminder
CTO & Vice President, R&D
|
7 593
-19.8%
7,53
57 139 $US
|
7 593
-19.8%
|
7,53
|
57 139 $US
|
|
|
2017-08-18 |
2017-08-17 |
V
Vente
|
Sweemer Timothy D
Chief Accounting Officer
|
12 012
-27.1%
7,62
91 529 $US
|
12 012
-27.1%
|
7,62
|
91 529 $US
|
|
|
2017-08-18 |
2017-08-17 |
V
Vente
|
Singh Parminder
CTO & Vice President, R&D
|
32 000
-45.5%
7,61
243 619 $US
|
32 000
-45.5%
|
7,61
|
243 619 $US
|
|
|
2017-08-18 |
2017-08-16 |
V
Vente
|
Sweemer Timothy D
Chief Accounting Officer
|
15 488
-25.9%
7,82
121 156 $US
|
15 488
-25.9%
|
7,82
|
121 156 $US
|
|
|
2017-07-21 |
2017-07-20 |
PlS
Vente planifiée
|
Sarret Joseph J.
Chief Business Officer
Dirigeant
|
2 038
-21.5%
8,95
18 232 $US
|
2 038
-21.5%
|
8,95
|
18 232 $US
|
|
|
2017-07-05 |
2017-06-30 |
A
Achat
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
301 004
+5.4%
7,71
2 319 236 $US
|
301 004
+5.4%
|
7,71
|
2 319 236 $US
|
|
|
2017-05-25 |
2017-05-25 |
A
Achat
|
PERCEPTIVE ADVISORS LLC
Actionnaire important
|
1 902 400
+52.2%
6,25
11 890 000 $US
|
1 902 400
+52.2%
|
6,25
|
11 890 000 $US
|
|
|
2016-05-20 |
2016-05-19 |
A
Achat
|
BJERKHOLT ERIC
Administrateur non-exécutif
|
6 341
+112.1%
3,70
23 453 $US
|
6 341
+112.1%
|
3,70
|
23 453 $US
|
|
|
2016-05-20 |
2016-05-19 |
A
Achat
|
BJERKHOLT ERIC
Administrateur non-exécutif
|
7 790
+165.4%
3,71
28 879 $US
|
7 790
+165.4%
|
3,71
|
28 879 $US
|
|
|
2016-05-20 |
2016-05-18 |
A
Achat
|
BJERKHOLT ERIC
Administrateur non-exécutif
|
5 659
+inf%
3,57
20 179 $US
|
5 659
+inf%
|
3,57
|
20 179 $US
|
|
|
2016-05-20 |
2016-05-18 |
A
Achat
|
BJERKHOLT ERIC
Administrateur non-exécutif
|
4 710
+inf%
3,54
16 688 $US
|
4 710
+inf%
|
3,54
|
16 688 $US
|
|
|
2016-05-17 |
2016-05-16 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
6 500
+22.9%
3,70
24 046 $US
|
6 500
+22.9%
|
3,70
|
24 046 $US
|
|
|
2016-05-17 |
2016-05-13 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
6 000
+26.8%
3,50
20 996 $US
|
6 000
+26.8%
|
3,50
|
20 996 $US
|
|
|
2016-05-16 |
2016-05-12 |
A
Achat
|
GREENWOOD DAVID
Administrateur non-exécutif
|
3 000
+inf%
3,58
10 742 $US
|
3 000
+inf%
|
3,58
|
10 742 $US
|
|
|
2015-02-26 |
2015-02-25 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
3 600
+19.2%
6,99
25 169 $US
|
3 600
+19.2%
|
6,99
|
25 169 $US
|
|
|
2014-11-24 |
2014-11-24 |
A
Achat
|
BREUIL ROBERT S
Chief Financial Officer
Dirigeant
|
1 600
+40.0%
5,40
8 640 $US
|
1 600
+40.0%
|
5,40
|
8 640 $US
|
|
|
2014-11-24 |
2014-11-21 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
9 000
+92.0%
5,34
48 055 $US
|
9 000
+92.0%
|
5,34
|
48 055 $US
|
|
|
2014-08-27 |
2014-08-27 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
300
+3.2%
6,20
1 860 $US
|
300
+3.2%
|
6,20
|
1 860 $US
|
|
|
2014-08-27 |
2014-08-26 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
1 000
+11.8%
6,14
6 144 $US
|
1 000
+11.8%
|
6,14
|
6 144 $US
|
|
|
2014-08-27 |
2014-08-25 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
1 278
+17.8%
6,05
7 726 $US
|
1 278
+17.8%
|
6,05
|
7 726 $US
|
|
|
2014-05-30 |
2014-05-30 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
2 400
+50.0%
7,08
16 982 $US
|
2 400
+50.0%
|
7,08
|
16 982 $US
|
|
|
2014-05-30 |
2014-05-29 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
2 900
+152.6%
7,08
20 518 $US
|
2 900
+152.6%
|
7,08
|
20 518 $US
|
|
|
2014-05-30 |
2014-05-28 |
A
Achat
|
STAPLE PETER D
President & CEO
Administrateur exécutif
|
1 900
+inf%
6,95
13 206 $US
|
1 900
+inf%
|
6,95
|
13 206 $US
|
|
|
2014-04-08 |
2014-04-08 |
A
Achat
|
ESSEX WOODLANDS HEALTH VENTURES FUND VII LP
Actionnaire important
|
400 000
+4.5%
8,00
3 200 000 $US
|
400 000
+4.5%
|
8,00
|
3 200 000 $US
|
|
|
2014-04-08 |
2014-04-08 |
A
Achat
|
Eastman Ronald W
Administrateur non-exécutif
Actionnaire important
|
400 000
+4.5%
8,00
3 200 000 $US
|
400 000
+4.5%
|
8,00
|
3 200 000 $US
|
|
