|
2023-07-18 |
2023-07-10 |
B
Compra
|
Consejero no ejecutivo
|
64 289
-22.8%
290,40
4.761.463 US$
|
64 289
-22.8%
|
290,40
|
4.761.463 US$
|
|
|
2023-04-06 |
2023-04-06 |
S
Venta
|
Gran accionista
|
6 874
+25.2%
265,26
2.233.250 US$
|
6 874
+25.2%
|
265,26
|
2.233.250 US$
|
|
|
2023-04-06 |
2023-04-05 |
S
Venta
|
Gran accionista
|
51 179
+18.8%
250,20
1.227.635 US$
|
51 179
+18.8%
|
250,20
|
1.227.635 US$
|
|
|
2023-04-06 |
2023-04-04 |
S
Venta
|
Gran accionista
|
4 810 623
-9.2%
0,16
769.700 US$
|
4 810 623
-9.2%
|
0,16
|
769.700 US$
|
|
|
2021-12-06 |
2021-12-03 |
B
Compra
|
Chief Business Officer
Oficial
|
8 200
+13.7%
2,45
20.083 US$
|
8 200
+13.7%
|
2,45
|
20.083 US$
|
|
|
2021-12-03 |
2021-12-01 |
S
Venta
|
Gran accionista
|
2 707 463
-4.9%
3,31
8.961.703 US$
|
2 707 463
-4.9%
|
3,31
|
8.961.703 US$
|
|
|
2020-04-28 |
2020-04-24 |
B
Compra
|
Gran accionista
|
9 090 909
+19.8%
1,10
10.000.000 US$
|
9 090 909
+19.8%
|
1,10
|
10.000.000 US$
|
|
|
2019-10-07 |
2019-10-04 |
B
Compra
|
Chief Medical Officer
|
40 000
+51.6%
0,50
20.000 US$
|
40 000
+51.6%
|
0,50
|
20.000 US$
|
|
|
2019-10-01 |
2019-10-01 |
B
Compra
|
Chief Business Officer
|
10 000
+20.0%
0,48
4.822 US$
|
10 000
+20.0%
|
0,48
|
4.822 US$
|
|
|
2019-10-01 |
2019-10-01 |
B
Compra
|
CFO and Head of BD
Consejero ejecutivo
|
12 000
+48.0%
0,47
5.676 US$
|
12 000
+48.0%
|
0,47
|
5.676 US$
|
|
|
2019-10-07 |
2019-09-30 |
B
Compra
|
Chief Medical Officer
|
14 500
+inf%
0,50
7.250 US$
|
14 500
+inf%
|
0,50
|
7.250 US$
|
|
|
2019-09-30 |
2019-09-30 |
B
Compra
|
CEO, President
Consejero ejecutivo
|
150 000
+32.7%
0,50
75.450 US$
|
150 000
+32.7%
|
0,50
|
75.450 US$
|
|
|
2019-09-24 |
2019-09-23 |
B
Compra
|
Gran accionista
|
20 000 000
+77.1%
0,50
10.000.000 US$
|
20 000 000
+77.1%
|
0,50
|
10.000.000 US$
|
|
|
2019-09-23 |
2019-09-19 |
B
Compra
|
|
10 000 000
+330.5%
0,50
5.000.000 US$
|
10 000 000
+330.5%
|
0,50
|
5.000.000 US$
|
|
|
2019-07-01 |
2019-06-27 |
B
Compra
|
Chief Medical Officer
|
8 000
+11.5%
1,07
8.560 US$
|
8 000
+11.5%
|
1,07
|
8.560 US$
|
|
|
2019-06-20 |
2019-06-20 |
B
Compra
|
Chief Medical Officer
|
42 000
+152.7%
0,89
37.380 US$
|
42 000
+152.7%
|
0,89
|
37.380 US$
|
|
|
2019-06-20 |
2019-06-20 |
B
Compra
|
Chief Medical Officer
|
10 000
+57.1%
0,78
7.800 US$
|
10 000
+57.1%
|
0,78
|
7.800 US$
|
|
|
2019-06-19 |
2019-06-19 |
B
Compra
|
Chief Business Officer
|
8 000
+19.0%
0,74
5.886 US$
|
8 000
+19.0%
|
0,74
|
5.886 US$
|
|
|
2019-06-19 |
2019-06-19 |
B
Compra
|
CEO, President
Consejero ejecutivo
|
144 000
+45.8%
0,73
105.336 US$
|
144 000
+45.8%
|
0,73
|
105.336 US$
|
|
|
2019-06-20 |
2019-06-18 |
B
Compra
|
Gran accionista
|
1 000 000
+4.0%
0,65
650.000 US$
|
1 000 000
+4.0%
|
0,65
|
650.000 US$
|
|
|
2019-06-18 |
2019-06-17 |
B
Compra
|
Gran accionista
|
1 000 000
+4.2%
0,62
618.000 US$
|
1 000 000
+4.2%
|
0,62
|
618.000 US$
|
|
|
2018-12-18 |
2018-12-17 |
B
Compra
|
Kariv Tomer
Consejero no ejecutivo
|
185 714
+inf%
1,40
260.000 US$
|
185 714
+inf%
|
1,40
|
260.000 US$
|
|
|
2018-12-18 |
2018-12-17 |
B
Compra
|
Kariv Tomer
Consejero no ejecutivo
|
331 429
+54.2%
1,40
464.001 US$
|
331 429
+54.2%
|
1,40
|
464.001 US$
|
|
|
2018-12-18 |
2018-12-17 |
B
Compra
|
Kariv Tomer
Consejero no ejecutivo
|
298 431
+54.2%
1,40
417.803 US$
|
298 431
+54.2%
|
1,40
|
417.803 US$
|
|
|
2018-12-18 |
2018-12-17 |
B
Compra
|
Kariv Tomer
Consejero no ejecutivo
|
612 997
+54.2%
1,40
858.196 US$
|
612 997
+54.2%
|
1,40
|
858.196 US$
|
|
|
2018-12-17 |
2018-12-13 |
B
Compra
|
PERCEPTIVE ADVISORS LLC
Gran accionista
|
14 285 714
+152.9%
1,40
20.000.000 US$
|
14 285 714
+152.9%
|
1,40
|
20.000.000 US$
|
|
|
2018-08-07 |
2018-08-06 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
8 100
+3.6%
1,93
15.607 US$
|
8 100
+3.6%
|
1,93
|
15.607 US$
|
|
|
2018-08-06 |
2018-08-03 |
B
Compra
|
Diaz-Mitoma Francisco
Chief Medical Officer
Oficial
|
6 000
+52.2%
2,10
12.600 US$
|
6 000
+52.2%
|
2,10
|
12.600 US$
|
|
|
2018-08-06 |
2018-08-03 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
13 500
+6.4%
2,01
27.111 US$
|
13 500
+6.4%
|
2,01
|
27.111 US$
|
|
|
2018-08-03 |
2018-08-03 |
B
Compra
|
Beattie Nell
Chief Business Officer
Oficial
|
2 000
+10.7%
2,01
4.011 US$
|
2 000
+10.7%
|
2,01
|
4.011 US$
|
|
|
2018-08-06 |
2018-08-02 |
B
Compra
|
Diaz-Mitoma Francisco
Chief Medical Officer
Oficial
|
3 000
+35.3%
2,20
6.600 US$
|
3 000
+35.3%
|
2,20
|
6.600 US$
|
|
|
2018-08-01 |
2018-07-31 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
16 800
+8.6%
2,28
38.237 US$
|
16 800
+8.6%
|
2,28
|
38.237 US$
|
|
|
2018-05-25 |
2018-05-24 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
11 000
+7.2%
2,99
32.890 US$
|
11 000
+7.2%
|
2,99
|
32.890 US$
|
|
|
2018-05-14 |
2018-05-11 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
7 100
+4.9%
2,91
20.661 US$
|
7 100
+4.9%
|
2,91
|
20.661 US$
|
|
|
2018-05-14 |
2018-05-11 |
B
Compra
|
Diaz-Mitoma Francisco
Chief Medical Officer
Oficial
|
4 500
+1.7%
3,13
14.085 US$
|
4 500
+1.7%
|
3,13
|
14.085 US$
|
|
|
2018-05-14 |
2018-05-11 |
B
Compra
|
Diaz-Mitoma Francisco
Chief Medical Officer
Oficial
|
5 500
+183.3%
2,98
16.390 US$
|
5 500
+183.3%
|
2,98
|
16.390 US$
|
|
|
2017-12-13 |
2017-12-12 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
4 609
+3.3%
3,88
17.883 US$
|
4 609
+3.3%
|
3,88
|
17.883 US$
|
|
|
2017-12-13 |
2017-12-12 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
5 391
+4.0%
3,89
20.971 US$
|
5 391
+4.0%
|
3,89
|
20.971 US$
|
|
|
2017-11-29 |
2017-11-28 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
15 000
+12.5%
4,75
71.250 US$
|
15 000
+12.5%
|
4,75
|
71.250 US$
|
|
|
2017-11-01 |
2017-10-30 |
B
Compra
|
Opko Health, Inc.
Gran accionista
|
655 738
+10.9%
3,05
2.000.001 US$
|
655 738
+10.9%
|
3,05
|
2.000.001 US$
|
|
|
2017-10-31 |
2017-10-30 |
B
Compra
|
GILLIS STEVEN
|
300 000
+11.0%
3,05
915.000 US$
|
300 000
+11.0%
|
3,05
|
915.000 US$
|
|
|
2017-10-31 |
2017-10-30 |
B
Compra
|
CHAWLA SAM
|
3 100 000
+49.6%
3,05
9.455.000 US$
|
3 100 000
+49.6%
|
3,05
|
9.455.000 US$
|
|
|
2017-10-30 |
2017-10-26 |
B
Compra
|
PERCEPTIVE ADVISORS LLC
Gran accionista
|
3 100 000
+49.6%
3,05
9.455.000 US$
|
3 100 000
+49.6%
|
3,05
|
9.455.000 US$
|
|
|
2017-08-22 |
2017-08-21 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
10 000
+9.1%
3,22
32.200 US$
|
10 000
+9.1%
|
3,22
|
32.200 US$
|
|
|
2017-08-22 |
2017-08-21 |
B
Compra
|
Diaz-Mitoma Francisco
Chief Medical Officer
|
3 000
+inf%
3,17
9.510 US$
|
3 000
+inf%
|
3,17
|
9.510 US$
|
|
|
2017-08-14 |
2017-08-10 |
B
Compra
|
Baxter Jeff
CEO, President
Consejero ejecutivo
|
10 000
+10.0%
3,28
32.800 US$
|
10 000
+10.0%
|
3,28
|
32.800 US$
|
|
|
2016-12-08 |
2016-12-06 |
B
Compra
|
PERCEPTIVE ADVISORS LLC
Gran accionista
|
3 383 955
+119.6%
3,05
10.321.063 US$
|
3 383 955
+119.6%
|
3,05
|
10.321.063 US$
|
|
|
2015-08-18 |
2015-08-14 |
B
Compra
|
PERCEPTIVE ADVISORS LLC
Gran accionista
|
650 000
+24.9%
2,08
1.352.000 US$
|
650 000
+24.9%
|
2,08
|
1.352.000 US$
|
|
|
2013-10-07 |
2013-09-30 |
B
Compra
|
Smith Murray George
Chief Financial Officer
Oficial
|
3 027
+33.7%
1,13
3.421 US$
|
3 027
+33.7%
|
1,13
|
3.421 US$
|
|
|
2013-08-22 |
2013-08-21 |
B
Compra
|
Smith Murray George
Chief Financial Officer
Oficial
|
1 973
+28.2%
1,10
2.170 US$
|
1 973
+28.2%
|
1,10
|
2.170 US$
|
|
|
2013-08-22 |
2013-08-20 |
B
Compra
|
Smith Murray George
Chief Financial Officer
Oficial
|
5 000
+250.0%
1,20
6.000 US$
|
5 000
+250.0%
|
1,20
|
6.000 US$
|
|
|
2013-08-22 |
2013-08-20 |
B
Compra
|
Smith Murray George
Chief Financial Officer
Oficial
|
2 000
+inf%
1,18
2.360 US$
|
2 000
+inf%
|
1,18
|
2.360 US$
|
|
|
2012-04-11 |
2012-04-09 |
B
Compra
|
Pratt Shannon
Consejero no ejecutivo
|
20 000
+33.3%
1,15
23.000 US$
|
20 000
+33.3%
|
1,15
|
23.000 US$
|
|
|
2012-04-11 |
2012-04-02 |
B
Compra
|
Pratt Shannon
Consejero no ejecutivo
|
20 000
+50.0%
1,10
21.960 US$
|
20 000
+50.0%
|
1,10
|
21.960 US$
|
|
|
2012-04-11 |
2012-03-19 |
B
Compra
|
Pratt Shannon
Consejero no ejecutivo
|
20 000
+100.0%
1,25
25.040 US$
|
20 000
+100.0%
|
1,25
|
25.040 US$
|
|
|
2012-04-11 |
2012-03-12 |
B
Compra
|
Pratt Shannon
Consejero no ejecutivo
|
7 000
+77.3%
1,10
7.679 US$
|
7 000
+77.3%
|
1,10
|
7.679 US$
|
|
|
2009-11-17 |
2009-11-13 |
B
Compra
|
Pratt Shannon
Consejero no ejecutivo
|
6 000
+39.5%
1,35
8.100 US$
|
6 000
+39.5%
|
1,35
|
8.100 US$
|
|
|
2009-12-31 |
2009-10-13 |
S
Venta
|
McChesney Shawn
|
1 500
-100.0%
1,59
2.392 US$
|
1 500
-100.0%
|
1,59
|
2.392 US$
|
|
|
2009-09-17 |
2009-09-15 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
401
-0.0%
1,90
762 US$
|
401
-0.0%
|
1,90
|
762 US$
|
|
|
2009-09-03 |
2009-09-02 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
16 029
-0.5%
1,96
31.394 US$
|
16 029
-0.5%
|
1,96
|
31.394 US$
|
|
|
2009-09-01 |
2009-08-31 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
599
-0.0%
1,95
1.168 US$
|
599
-0.0%
|
1,95
|
1.168 US$
|
|
|
2009-09-01 |
2009-08-28 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
1 022
-0.0%
1,95
1.995 US$
|
1 022
-0.0%
|
1,95
|
1.995 US$
|
|
|
2009-08-27 |
2009-08-27 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
1 699
-0.1%
1,95
3.313 US$
|
1 699
-0.1%
|
1,95
|
3.313 US$
|
|
|
2009-08-27 |
2009-08-26 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
1 563
-0.1%
1,95
3.048 US$
|
1 563
-0.1%
|
1,95
|
3.048 US$
|
|
|
2009-08-27 |
2009-08-25 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
289
-0.0%
1,95
564 US$
|
289
-0.0%
|
1,95
|
564 US$
|
|
|
2009-08-14 |
2009-08-14 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
8 600
-0.3%
2,00
17.203 US$
|
8 600
-0.3%
|
2,00
|
17.203 US$
|
|
|
2009-08-14 |
2009-08-13 |
S
Venta
|
PAULSON CHESTER L F
Chairman
Consejero ejecutivo
Gran accionista
|
1 400
-0.0%
2,15
3.010 US$
|
1 400
-0.0%
|
2,15
|
3.010 US$
|
|
|
2009-09-01 |
2009-08-12 |
S
Venta
|
PAULSON CHARLES
Consejero no ejecutivo
|
1 000
-100.0%
2,50
2.500 US$
|
1 000
-100.0%
|
2,50
|
2.500 US$
|
|
|
2008-03-05 |
2008-02-29 |
S
Venta
|
STRIPLIN HARRY L
|
1 237
-4.3%
4,99
6.168 US$
|
1 237
-4.3%
|
4,99
|
6.168 US$
|
|
|
2008-01-24 |
2008-01-24 |
S
Venta
|
STRIPLIN HARRY L
|
1 000
-3.3%
5,65
5.650 US$
|
1 000
-3.3%
|
5,65
|
5.650 US$
|
|
|
2008-01-10 |
2008-01-09 |
S
Venta
|
STRIPLIN HARRY L
|
1 000
-3.2%
5,15
5.150 US$
|
1 000
-3.2%
|
5,15
|
5.150 US$
|
|
|
2007-12-18 |
2007-12-14 |
S
Venta
|
STRIPLIN HARRY L
|
900
-2.8%
5,00
4.500 US$
|
900
-2.8%
|
5,00
|
4.500 US$
|
|
|
2007-12-18 |
2007-12-14 |
S
Venta
|
STRIPLIN HARRY L
|
100
-0.3%
5,00
500 US$
|
100
-0.3%
|
5,00
|
500 US$
|
|
|
2007-10-04 |
2007-10-04 |
S
Venta
|
MAXFIELD MARGARET L
|
1 000
-10.9%
5,20
5.203 US$
|
1 000
-10.9%
|
5,20
|
5.203 US$
|
|
|
2007-06-22 |
2007-06-21 |
S
Venta
|
MAXFIELD MARGARET L
|
500
-5.2%
5,23
2.613 US$
|
500
-5.2%
|
5,23
|
2.613 US$
|
|