|
2022-07-27 |
2022-07-25 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
19,557
-4.5%
42.90
839,066
USD
|
19,557
-4.5%
|
42.90
|
839,066
USD
|
|
|
2022-07-27 |
2022-07-25 |
S
Sale
|
Urist Marshall
EVP, Research & Investments
Officer
|
3,600
-15.4%
43.05
154,985
USD
|
3,600
-15.4%
|
43.05
|
154,985
USD
|
|
|
2022-06-29 |
2022-06-29 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
30,000
-6.6%
42.17
1,265,238
USD
|
30,000
-6.6%
|
42.17
|
1,265,238
USD
|
|
|
2022-06-24 |
2022-06-24 |
S
Sale
|
Urist Marshall
EVP, Research & Investments
Officer
|
23,333
-50.0%
43.19
1,007,694
USD
|
23,333
-50.0%
|
43.19
|
1,007,694
USD
|
|
|
2022-06-10 |
2022-06-08 |
S
Sale
|
Reddoch James F.
EVP & Chief Scientific Officer
Officer
|
100,000
-9.8%
41.56
4,155,900
USD
|
100,000
-9.8%
|
41.56
|
4,155,900
USD
|
|
|
2022-05-31 |
2022-05-27 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
13,974
-3.1%
40.77
569,754
USD
|
13,974
-3.1%
|
40.77
|
569,754
USD
|
|
|
2022-05-31 |
2022-05-27 |
S
Sale
|
Reddoch James F.
EVP & Chief Scientific Officer
Officer
|
75,000
-6.8%
41.08
3,081,008
USD
|
75,000
-6.8%
|
41.08
|
3,081,008
USD
|
|
|
2022-05-31 |
2022-05-26 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
86,026
-16.2%
40.21
3,459,338
USD
|
86,026
-16.2%
|
40.21
|
3,459,338
USD
|
|
|
2022-05-25 |
2022-05-23 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
100,000
-15.9%
40.27
4,026,770
USD
|
100,000
-15.9%
|
40.27
|
4,026,770
USD
|
|
|
2022-05-23 |
2022-05-20 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
123,696
-21.5%
39.28
4,858,655
USD
|
123,696
-21.5%
|
39.28
|
4,858,655
USD
|
|
|
2022-05-23 |
2022-05-19 |
S
Sale
|
Reddoch James F.
EVP & Chief Scientific Officer
Officer
|
75,000
-6.4%
40.44
3,033,128
USD
|
75,000
-6.4%
|
40.44
|
3,033,128
USD
|
|
|
2022-05-23 |
2022-05-19 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
26,304
-4.4%
40.09
1,054,651
USD
|
26,304
-4.4%
|
40.09
|
1,054,651
USD
|
|
|
2022-05-16 |
2022-05-16 |
S
Sale
|
Urist Marshall
EVP, Research & Investments
Officer
|
23,333
-33.3%
39.85
929,836
USD
|
23,333
-33.3%
|
39.85
|
929,836
USD
|
|
|
2022-03-30 |
2022-03-29 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
60,000
-9.1%
38.59
2,315,322
USD
|
60,000
-9.1%
|
38.59
|
2,315,322
USD
|
|
|
2022-03-21 |
2022-03-21 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
14,322
-100.0%
39.05
559,288
USD
|
14,322
-100.0%
|
39.05
|
559,288
USD
|
|
|
2022-03-21 |
2022-03-21 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
25,545
-100.0%
39.05
997,558
USD
|
25,545
-100.0%
|
39.05
|
997,558
USD
|
|
|
2022-03-21 |
2022-03-18 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
56,181
-39.7%
39.77
2,234,094
USD
|
56,181
-39.7%
|
39.77
|
2,234,094
USD
|
|
|
2022-03-21 |
2022-03-18 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
26,238
-64.7%
39.38
1,033,334
USD
|
26,238
-64.7%
|
39.38
|
1,033,334
USD
|
|
|
2022-03-21 |
2022-03-18 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
46,803
-64.7%
39.38
1,843,247
USD
|
46,803
-64.7%
|
39.38
|
1,843,247
USD
|
|
|
2022-02-25 |
2022-02-24 |
B
Purchase
|
Fernandez Henry A
Non-Executive Director
|
32,500
+126.5%
37.49
1,218,373
USD
|
32,500
+126.5%
|
37.49
|
1,218,373
USD
|
|
|
2021-11-18 |
2021-11-17 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
31,341
-2.7%
42.33
1,326,636
USD
|
31,341
-2.7%
|
42.33
|
1,326,636
USD
|
|
|
2021-11-18 |
2021-11-17 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
38,815
-2.1%
42.35
1,643,749
USD
|
38,815
-2.1%
|
42.35
|
1,643,749
USD
|
|
|
2021-11-18 |
2021-11-17 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
69,233
-12.2%
42.35
2,931,900
USD
|
69,233
-12.2%
|
42.35
|
2,931,900
USD
|
|
|
2021-11-18 |
2021-11-17 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
62,435
-9.1%
42.39
2,646,401
USD
|
62,435
-9.1%
|
42.39
|
2,646,401
USD
|
|
|
2021-11-18 |
2021-11-17 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
84,148
-11.8%
42.39
3,566,832
USD
|
84,148
-11.8%
|
42.39
|
3,566,832
USD
|
|
|
2021-11-18 |
2021-11-16 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
12,565
-1.8%
42.01
527,805
USD
|
12,565
-1.8%
|
42.01
|
527,805
USD
|
|
|
2021-11-18 |
2021-11-16 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
65,852
-8.4%
42.12
2,773,660
USD
|
65,852
-8.4%
|
42.12
|
2,773,660
USD
|
|
|
2021-11-18 |
2021-11-16 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
27,341
-5.2%
43.19
1,180,822
USD
|
27,341
-5.2%
|
43.19
|
1,180,822
USD
|
|
|
2021-11-18 |
2021-11-16 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
72,659
-12.2%
42.33
3,075,379
USD
|
72,659
-12.2%
|
42.33
|
3,075,379
USD
|
|
|
2021-06-29 |
2021-06-29 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
479,800
-12.2%
41.26
19,794,437
USD
|
479,800
-12.2%
|
41.26
|
19,794,437
USD
|
|
|
2021-06-29 |
2021-06-29 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
1,200
-0.0%
42.01
50,409
USD
|
1,200
-0.0%
|
42.01
|
50,409
USD
|
|
|
2021-06-29 |
2021-06-28 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
167,448
-4.1%
42.11
7,051,269
USD
|
167,448
-4.1%
|
42.11
|
7,051,269
USD
|
|
|
2021-06-29 |
2021-06-25 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
487,364
-10.6%
42.69
20,807,519
USD
|
487,364
-10.6%
|
42.69
|
20,807,519
USD
|
|
|
2021-06-29 |
2021-06-25 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
179,100
-16.1%
42.81
7,666,501
USD
|
179,100
-16.1%
|
42.81
|
7,666,501
USD
|
|
|
2021-06-14 |
2021-06-10 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
10,000
-4.0%
46.45
464,491
USD
|
10,000
-4.0%
|
46.45
|
464,491
USD
|
|
|
2021-06-14 |
2021-06-10 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
40,000
-4.3%
46.52
1,860,772
USD
|
40,000
-4.3%
|
46.52
|
1,860,772
USD
|
|
|
2021-06-14 |
2021-06-10 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
20,000
-3.1%
46.46
929,106
USD
|
20,000
-3.1%
|
46.46
|
929,106
USD
|
|
|
2021-06-08 |
2021-06-08 |
S
Sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
50,000
-3.8%
46.43
2,321,540
USD
|
50,000
-3.8%
|
46.43
|
2,321,540
USD
|
|
|
2021-06-08 |
2021-06-07 |
S
Sale
|
Urist Marshall
EVP & Co-Head of R&I
Officer
|
16,568
-100.0%
47.02
779,059
USD
|
16,568
-100.0%
|
47.02
|
779,059
USD
|
|
|
2021-06-08 |
2021-06-07 |
PS
Planned sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
2,210
-0.2%
47.01
103,896
USD
|
2,210
-0.2%
|
47.01
|
103,896
USD
|
|
|
2021-06-08 |
2021-06-07 |
PS
Planned sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
47,790
-3.5%
46.57
2,225,523
USD
|
47,790
-3.5%
|
46.57
|
2,225,523
USD
|
|
|
2021-06-08 |
2021-06-04 |
S
Sale
|
Urist Marshall
EVP & Co-Head of R&I
Officer
|
16,566
-50.0%
45.13
747,662
USD
|
16,566
-50.0%
|
45.13
|
747,662
USD
|
|
|
2021-06-08 |
2021-06-04 |
S
Sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
100,000
-6.8%
44.60
4,459,730
USD
|
100,000
-6.8%
|
44.60
|
4,459,730
USD
|
|
|
2021-06-04 |
2021-06-02 |
S
Sale
|
Urist Marshall
EVP & Co-Head Research & Inv.
Officer
|
14,566
-30.5%
41.52
604,850
USD
|
14,566
-30.5%
|
41.52
|
604,850
USD
|
|
|
2021-06-04 |
2021-06-02 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
50,000
-4.5%
42.13
2,106,385
USD
|
50,000
-4.5%
|
42.13
|
2,106,385
USD
|
|
|
2021-06-04 |
2021-06-02 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
12,500
-1.7%
42.09
526,128
USD
|
12,500
-1.7%
|
42.09
|
526,128
USD
|
|
|
2021-05-24 |
2021-05-21 |
S
Sale
|
Urist Marshall
EVP & Co-Head Research & Inv.
Officer
|
100
-0.2%
41.00
4,100
USD
|
100
-0.2%
|
41.00
|
4,100
USD
|
|
|
2021-05-24 |
2021-05-20 |
S
Sale
|
Urist Marshall
EVP & Co-Head Research & Inv.
Officer
|
1,900
-3.8%
41.08
78,059
USD
|
1,900
-3.8%
|
41.08
|
78,059
USD
|
|
|
2021-04-16 |
2021-04-14 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
55,898
-21.8%
42.14
2,355,486
USD
|
55,898
-21.8%
|
42.14
|
2,355,486
USD
|
|
|
2021-04-16 |
2021-04-14 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
13,924
-21.8%
42.12
586,434
USD
|
13,924
-21.8%
|
42.12
|
586,434
USD
|
|
|
2021-04-16 |
2021-04-14 |
S
Sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
55,714
-21.8%
42.10
2,345,593
USD
|
55,714
-21.8%
|
42.10
|
2,345,593
USD
|
|
|
2021-04-14 |
2021-04-12 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
360
-0.1%
42.32
15,235
USD
|
360
-0.1%
|
42.32
|
15,235
USD
|
|
|
2021-04-14 |
2021-04-12 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
89
-0.1%
42.32
3,766
USD
|
89
-0.1%
|
42.32
|
3,766
USD
|
|
|
2021-04-14 |
2021-04-12 |
S
Sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
359
-0.1%
42.32
15,193
USD
|
359
-0.1%
|
42.32
|
15,193
USD
|
|
|
2021-03-24 |
2021-03-22 |
S
Sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
43,927
-14.6%
46.32
2,034,519
USD
|
43,927
-14.6%
|
46.32
|
2,034,519
USD
|
|
|
2021-03-24 |
2021-03-22 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
100
-0.0%
47.04
4,704
USD
|
100
-0.0%
|
47.04
|
4,704
USD
|
|
|
2021-03-24 |
2021-03-22 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
43,642
-14.5%
46.32
2,021,436
USD
|
43,642
-14.5%
|
46.32
|
2,021,436
USD
|
|
|
2021-03-24 |
2021-03-22 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
10,987
-14.6%
46.34
509,086
USD
|
10,987
-14.6%
|
46.34
|
509,086
USD
|
|
|
2021-03-05 |
2021-03-03 |
S
Sale
|
Coyne Terrance P.
EVP & CFO
Officer
|
1,456
-0.7%
46.83
68,184
USD
|
1,456
-0.7%
|
46.83
|
68,184
USD
|
|
|
2021-03-05 |
2021-03-03 |
S
Sale
|
Coyne Terrance P.
EVP & CFO
Officer
|
11,001
-5.2%
45.86
504,459
USD
|
11,001
-5.2%
|
45.86
|
504,459
USD
|
|
|
2021-03-05 |
2021-03-03 |
S
Sale
|
Coyne Terrance P.
EVP & CFO
Officer
|
57,723
-21.4%
45.09
2,602,465
USD
|
57,723
-21.4%
|
45.09
|
2,602,465
USD
|
|
|
2021-03-05 |
2021-03-03 |
S
Sale
|
Coyne Terrance P.
EVP & CFO
Officer
|
29,820
-9.9%
43.71
1,303,343
USD
|
29,820
-9.9%
|
43.71
|
1,303,343
USD
|
|
|
2021-03-04 |
2021-03-02 |
S
Sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
3,510
-1.2%
47.84
167,925
USD
|
3,510
-1.2%
|
47.84
|
167,925
USD
|
|
|
2021-03-04 |
2021-03-02 |
S
Sale
|
Coyne Terrance P.
EVP & CFO
Officer
|
5,022
-1.6%
47.88
240,429
USD
|
5,022
-1.6%
|
47.88
|
240,429
USD
|
|
|
2021-03-04 |
2021-03-02 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
3,510
-1.2%
47.85
167,948
USD
|
3,510
-1.2%
|
47.85
|
167,948
USD
|
|
|
2021-03-04 |
2021-03-02 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
96,490
-24.1%
46.89
4,524,368
USD
|
96,490
-24.1%
|
46.89
|
4,524,368
USD
|
|
|
2021-03-04 |
2021-03-02 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
2,625
-3.4%
47.84
125,575
USD
|
2,625
-3.4%
|
47.84
|
125,575
USD
|
|
|
2021-03-04 |
2021-03-02 |
S
Sale
|
Reddoch James F.
EVP, Research & Investments
Officer
|
96,490
-24.1%
46.89
4,524,233
USD
|
96,490
-24.1%
|
46.89
|
4,524,233
USD
|
|
|
2021-03-04 |
2021-03-02 |
S
Sale
|
Coyne Terrance P.
EVP & CFO
Officer
|
94,978
-23.7%
46.89
4,453,661
USD
|
94,978
-23.7%
|
46.89
|
4,453,661
USD
|
|
|
2021-03-04 |
2021-03-02 |
S
Sale
|
Lloyd George W.
EVP, Investments & GC
Officer
|
22,375
-22.4%
46.89
1,049,258
USD
|
22,375
-22.4%
|
46.89
|
1,049,258
USD
|
|
|
2021-02-26 |
2021-02-25 |
B
Purchase
|
Fernandez Henry A
Non-Executive Director
|
25,700
+inf%
46.83
1,203,480
USD
|
25,700
+inf%
|
46.83
|
1,203,480
USD
|
|
|
2020-12-18 |
2020-12-18 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Major owner
|
101,050
-0.3%
44.02
4,448,221
USD
|
101,050
-0.3%
|
44.02
|
4,448,221
USD
|
|
|
2020-12-18 |
2020-12-17 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Major owner
|
7,200,000
-15.6%
43.92
316,224,000
USD
|
7,200,000
-15.6%
|
43.92
|
316,224,000
USD
|
|
|
2020-10-22 |
2020-10-20 |
S
Sale
|
RIGGS RORY B
Non-Executive Director
|
463,200
-100.0%
42.00
19,454,400
USD
|
463,200
-100.0%
|
42.00
|
19,454,400
USD
|
|
|
2020-06-23 |
2020-06-18 |
B
Purchase
|
Coyne Terrance P.
EVP & CFO
Officer
|
1,450
+inf%
28.00
40,600
USD
|
1,450
+inf%
|
28.00
|
40,600
USD
|
|
