|
2019-10-02 |
2019-10-01 |
PS
Planned sale
|
SUVARI TRICIA BORGA
Chief Legal Officer
|
3,249
-19.4%
48.70
158,226
USD
|
3,249
-19.4%
|
48.70
|
158,226
USD
|
|
|
2019-09-13 |
2019-09-11 |
S
Sale
|
Calhoun Lesley Ann
See Remarks
|
2,765
-75.7%
54.36
150,296
USD
|
2,765
-75.7%
|
54.36
|
150,296
USD
|
|
|
2019-02-14 |
2019-02-12 |
PS
Planned sale
|
Calhoun Lesley Ann
See Remarks
Officer
|
354
-25.5%
50.45
17,860
USD
|
354
-25.5%
|
50.45
|
17,860
USD
|
|
|
2018-08-20 |
2018-08-17 |
S
Sale
|
Calhoun Lesley Ann
See Remarks
Officer
|
300
-26.4%
49.19
14,756
USD
|
300
-26.4%
|
49.19
|
14,756
USD
|
|
|
2018-08-20 |
2018-08-16 |
S
Sale
|
Calhoun Lesley Ann
See Remarks
Officer
|
1,500
-56.9%
50.01
75,020
USD
|
1,500
-56.9%
|
50.01
|
75,020
USD
|
|
|
2018-08-20 |
2018-08-16 |
S
Sale
|
Calhoun Lesley Ann
See Remarks
Officer
|
204
-15.2%
49.97
10,194
USD
|
204
-15.2%
|
49.97
|
10,194
USD
|
|
|
2018-07-10 |
2018-07-09 |
S
Sale
|
Calhoun Lesley Ann
See Remarks
Officer
|
2,295
-85.5%
44.27
101,609
USD
|
2,295
-85.5%
|
44.27
|
101,609
USD
|
|
|
2018-07-10 |
2018-07-06 |
S
Sale
|
Calhoun Lesley Ann
See Remarks
Officer
|
1,000
-72.0%
44.01
44,005
USD
|
1,000
-72.0%
|
44.01
|
44,005
USD
|
|
|
2018-07-10 |
2018-07-06 |
S
Sale
|
PATRICK DEVAL L
Non-Executive Director
|
42,379
-100.0%
43.40
1,839,283
USD
|
42,379
-100.0%
|
43.40
|
1,839,283
USD
|
|
|
2018-05-21 |
2018-05-17 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,400
-1.0%
48.25
67,550
USD
|
1,400
-1.0%
|
48.25
|
67,550
USD
|
|
|
2018-05-21 |
2018-05-17 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,600
-1.2%
48.25
77,200
USD
|
1,600
-1.2%
|
48.25
|
77,200
USD
|
|
|
2018-04-19 |
2018-04-17 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,400
-1.0%
45.50
63,700
USD
|
1,400
-1.0%
|
45.50
|
63,700
USD
|
|
|
2018-04-19 |
2018-04-17 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,600
-1.1%
45.50
72,800
USD
|
1,600
-1.1%
|
45.50
|
72,800
USD
|
|
|
2018-03-20 |
2018-03-16 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,400
-1.0%
54.15
75,810
USD
|
1,400
-1.0%
|
54.15
|
75,810
USD
|
|
|
2018-03-20 |
2018-03-16 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,600
-1.1%
54.15
86,640
USD
|
1,600
-1.1%
|
54.15
|
86,640
USD
|
|
|
2018-03-05 |
2018-03-05 |
S
Sale
|
Calhoun Lesley Ann
See Remarks
Officer
|
99
-20.3%
60.35
5,975
USD
|
99
-20.3%
|
60.35
|
5,975
USD
|
|
|
2018-02-21 |
2018-02-16 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,400
-1.0%
62.95
88,130
USD
|
1,400
-1.0%
|
62.95
|
88,130
USD
|
|
|
2018-02-21 |
2018-02-16 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,600
-1.1%
62.95
100,720
USD
|
1,600
-1.1%
|
62.95
|
100,720
USD
|
|
|
2018-02-02 |
2018-02-01 |
PS
Planned sale
|
Radovich Peter
See Remarks
Officer
|
812
-10.6%
57.30
46,528
USD
|
812
-10.6%
|
57.30
|
46,528
USD
|
|
|
2018-01-25 |
2018-01-23 |
PS
Planned sale
|
Radovich Peter
See Remarks
Officer
|
30,000
-89.3%
60.00
1,800,000
USD
|
30,000
-89.3%
|
60.00
|
1,800,000
USD
|
|
|
2018-01-18 |
2018-01-17 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,600
-1.2%
52.85
84,560
USD
|
1,600
-1.2%
|
52.85
|
84,560
USD
|
|
|
2018-01-18 |
2018-01-17 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,400
-1.0%
52.85
73,990
USD
|
1,400
-1.0%
|
52.85
|
73,990
USD
|
|
|
2018-01-11 |
2018-01-10 |
PS
Planned sale
|
Radovich Peter
See Remarks
Officer
|
15,000
-84.8%
50.00
750,000
USD
|
15,000
-84.8%
|
50.00
|
750,000
USD
|
|
|
2017-12-19 |
2017-12-19 |
B
Purchase
|
PERCEPTIVE ADVISORS LLC
Major owner
|
175,000
+3.7%
38.00
6,650,000
USD
|
175,000
+3.7%
|
38.00
|
6,650,000
USD
|
|
|
2017-12-20 |
2017-12-18 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,400
-1.0%
36.55
51,170
USD
|
1,400
-1.0%
|
36.55
|
51,170
USD
|
|
|
2017-12-20 |
2017-12-18 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,600
-1.2%
36.55
58,480
USD
|
1,600
-1.2%
|
36.55
|
58,480
USD
|
|
|
2017-11-21 |
2017-11-17 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,400
-1.0%
39.75
55,650
USD
|
1,400
-1.0%
|
39.75
|
55,650
USD
|
|
|
2017-11-21 |
2017-11-17 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,600
-1.2%
39.75
63,600
USD
|
1,600
-1.2%
|
39.75
|
63,600
USD
|
|
|
2017-10-31 |
2017-10-30 |
PS
Planned sale
|
Radovich Peter
Senior VP, Operations
|
12,500
-100.0%
35.00
437,500
USD
|
12,500
-100.0%
|
35.00
|
437,500
USD
|
|
|
2017-10-27 |
2017-10-27 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
15,600
-18.7%
34.09
531,770
USD
|
15,600
-18.7%
|
34.09
|
531,770
USD
|
|
|
2017-10-27 |
2017-10-26 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
54,400
-39.5%
33.93
1,845,781
USD
|
54,400
-39.5%
|
33.93
|
1,845,781
USD
|
|
|
2017-10-18 |
2017-10-17 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,400
-1.0%
32.65
45,710
USD
|
1,400
-1.0%
|
32.65
|
45,710
USD
|
|
|
2017-10-18 |
2017-10-17 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,600
-1.1%
32.65
52,240
USD
|
1,600
-1.1%
|
32.65
|
52,240
USD
|
|
|
2017-10-05 |
2017-10-04 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2017-10-05 |
2017-10-04 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2017-10-05 |
2017-10-04 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2017-10-05 |
2017-10-04 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2017-10-05 |
2017-10-03 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2017-10-05 |
2017-10-03 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2017-10-02 |
2017-09-29 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,400
-1.0%
30.00
42,000
USD
|
1,400
-1.0%
|
30.00
|
42,000
USD
|
|
|
2017-10-02 |
2017-09-29 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,600
-1.1%
30.00
48,000
USD
|
1,600
-1.1%
|
30.00
|
48,000
USD
|
|
|
2017-09-05 |
2017-08-31 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,400
-1.0%
30.00
42,000
USD
|
1,400
-1.0%
|
30.00
|
42,000
USD
|
|
|
2017-09-05 |
2017-08-31 |
PS
Planned sale
|
Choi Jung
See Remarks
|
1,600
-1.1%
30.00
48,000
USD
|
1,600
-1.1%
|
30.00
|
48,000
USD
|
|
|
2017-09-05 |
2017-08-31 |
PS
Planned sale
|
Radovich Peter
See Remarks
|
2,410
-47.3%
30.00
72,300
USD
|
2,410
-47.3%
|
30.00
|
72,300
USD
|
|
|
2017-07-27 |
2017-07-25 |
S
Sale
|
PATRICK DEVAL L
Non-Executive Director
|
27,053
-100.0%
29.69
803,204
USD
|
27,053
-100.0%
|
29.69
|
803,204
USD
|
|
|
2017-07-25 |
2017-07-21 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,400
-1.0%
30.00
42,000
USD
|
1,400
-1.0%
|
30.00
|
42,000
USD
|
|
|
2017-07-25 |
2017-07-21 |
PS
Planned sale
|
Choi Jung
See Remarks
Officer
|
1,600
-1.1%
30.00
48,000
USD
|
1,600
-1.1%
|
30.00
|
48,000
USD
|
|
|
2017-06-22 |
2017-06-02 |
S
Sale
|
HOMCY CHARLES J
|
31,742
-18.7%
27.64
877,203
USD
|
31,742
-18.7%
|
27.64
|
877,203
USD
|
|
|
2017-06-22 |
2017-06-02 |
S
Sale
|
HOMCY CHARLES J
|
49,959
-22.8%
26.92
1,344,921
USD
|
49,959
-22.8%
|
26.92
|
1,344,921
USD
|
|
|
2017-06-22 |
2017-06-01 |
S
Sale
|
HOMCY CHARLES J
|
18,299
-7.7%
26.58
486,345
USD
|
18,299
-7.7%
|
26.58
|
486,345
USD
|
|
|
2017-04-10 |
2017-04-06 |
S
Sale
|
TEPPER ROBERT I
Major owner
|
31,225
-12.0%
33.23
1,037,576
USD
|
31,225
-12.0%
|
33.23
|
1,037,576
USD
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
Third Rock Ventures II, L.P.
Major owner
|
10,900
-6.9%
28.73
313,146
USD
|
10,900
-6.9%
|
28.73
|
313,146
USD
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
Third Rock Ventures II, L.P.
Major owner
|
7,279
-4.4%
27.69
201,526
USD
|
7,279
-4.4%
|
27.69
|
201,526
USD
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
Third Rock Ventures II, L.P.
Major owner
|
27,115
-14.2%
26.95
730,803
USD
|
27,115
-14.2%
|
26.95
|
730,803
USD
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
Third Rock Ventures II, L.P.
Major owner
|
1,000,000
-77.8%
25.50
25,500,000
USD
|
1,000,000
-77.8%
|
25.50
|
25,500,000
USD
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
Third Rock Ventures II, L.P.
Major owner
|
1,000,000
-13.4%
25.50
25,500,000
USD
|
1,000,000
-13.4%
|
25.50
|
25,500,000
USD
|
|
|
2016-12-20 |
2016-12-16 |
S
Sale
|
STARR KEVIN P
Major owner
|
108,955
-56.9%
16.00
1,743,345
USD
|
108,955
-56.9%
|
16.00
|
1,743,345
USD
|
|
|
2016-11-16 |
2016-11-14 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2016-11-16 |
2016-11-14 |
S
Sale
|
Third Rock Ventures II, L.P.
Major owner
|
1,000,000
-43.8%
19.36
19,360,000
USD
|
1,000,000
-43.8%
|
19.36
|
19,360,000
USD
|
|
|
2016-11-16 |
2016-11-14 |
S
Sale
|
HOMCY CHARLES J
Non-Executive Director
|
0
0.00
0
USD
|
0
|
0.00
|
0
USD
|
|
|
2016-11-16 |
2016-11-14 |
S
Sale
|
Third Rock Ventures II, L.P.
Major owner
|
1,000,000
-9.5%
19.36
19,360,000
USD
|
1,000,000
-9.5%
|
19.36
|
19,360,000
USD
|
|
|
2016-01-07 |
2016-01-07 |
B
Purchase
|
Schembri John
See Remarks
Officer
|
1,000
+200.0%
22.36
22,360
USD
|
1,000
+200.0%
|
22.36
|
22,360
USD
|
|
|
2015-12-23 |
2015-12-22 |
B
Purchase
|
Ramos Eleanor
Chief Medical Officer
Officer
|
1,000
+10.0%
30.28
30,280
USD
|
1,000
+10.0%
|
30.28
|
30,280
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
LOVE TED W
See Remarks
Executive Director
|
2,500
+inf%
20.00
50,000
USD
|
2,500
+inf%
|
20.00
|
50,000
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
LOVE TED W
See Remarks
Executive Director
|
2,500
+inf%
20.00
50,000
USD
|
2,500
+inf%
|
20.00
|
50,000
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
Sham Hing
SVP of Chemistry
Officer
|
2,000
+5.8%
20.00
40,000
USD
|
2,000
+5.8%
|
20.00
|
40,000
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
Schembri John
See Remarks
Officer
|
500
+inf%
20.00
10,000
USD
|
500
+inf%
|
20.00
|
10,000
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
PERRY MARK L
Non-Executive Director
|
5,000
+23.3%
20.00
100,000
USD
|
5,000
+23.3%
|
20.00
|
100,000
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
LOVE TED W
See Remarks
Executive Director
|
5,000
+0.4%
20.00
100,000
USD
|
5,000
+0.4%
|
20.00
|
100,000
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
Choi Jung
See Remarks
Officer
|
25,000
+17.5%
20.00
500,000
USD
|
25,000
+17.5%
|
20.00
|
500,000
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
Radovich Peter
See Remarks
Officer
|
12,500
+inf%
20.00
250,000
USD
|
12,500
+inf%
|
20.00
|
250,000
USD
|
|
|
2016-01-07 |
2015-08-17 |
B
Purchase
|
PATRICK DEVAL L
Non-Executive Director
|
2,500
+inf%
20.00
50,000
USD
|
2,500
+inf%
|
20.00
|
50,000
USD
|
|
|
2015-12-23 |
2015-08-17 |
B
Purchase
|
Ramos Eleanor
Chief Medical Officer
Officer
|
10,000
+inf%
20.00
200,000
USD
|
10,000
+inf%
|
20.00
|
200,000
USD
|
|
