2020-05-15 |
2020-05-13 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
5,905
-6.7%
22.64
133,689
USD
|
5,905
-6.7%
|
22.64
|
133,689
USD
|
|
2020-05-15 |
2020-05-13 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
11,969
-12.0%
21.21
253,862
USD
|
11,969
-12.0%
|
21.21
|
253,862
USD
|
|
2020-05-15 |
2020-05-13 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
1,380
-1.4%
20.92
28,870
USD
|
1,380
-1.4%
|
20.92
|
28,870
USD
|
|
2020-05-15 |
2020-05-13 |
PS
Planned sale
|
Dreyer Scott
EVP & Chief Commercial Officer
Officer
|
4,434
-8.4%
22.61
100,253
USD
|
4,434
-8.4%
|
22.61
|
100,253
USD
|
|
2020-05-15 |
2020-05-13 |
PS
Planned sale
|
Fleming Alison B
Chief Technology Officer
Officer
|
5,261
-4.7%
21.12
111,112
USD
|
5,261
-4.7%
|
21.12
|
111,112
USD
|
|
2020-01-22 |
2020-01-21 |
PS
Planned sale
|
Heffernan Michael Thomas
|
32,700
-23.4%
22.69
741,963
USD
|
32,700
-23.4%
|
22.69
|
741,963
USD
|
|
2020-01-22 |
2020-01-21 |
PS
Planned sale
|
Heffernan Michael Thomas
|
262,587
-65.3%
21.84
5,734,900
USD
|
262,587
-65.3%
|
21.84
|
5,734,900
USD
|
|
2020-01-16 |
2020-01-14 |
PS
Planned sale
|
Dreyer Scott
EVP & Chief Commercial Officer
|
1,321
-3.6%
23.87
31,532
USD
|
1,321
-3.6%
|
23.87
|
31,532
USD
|
|
2019-11-13 |
2019-11-08 |
S
Sale
|
Fleming Alison B
Chief Technology Officer
Officer
|
25,000
-25.4%
19.44
486,000
USD
|
25,000
-25.4%
|
19.44
|
486,000
USD
|
|
2019-11-13 |
2019-11-08 |
S
Sale
|
Hirsch David
Non-Executive Director
|
25,000
-59.4%
19.33
483,250
USD
|
25,000
-59.4%
|
19.33
|
483,250
USD
|
|
2019-11-08 |
2019-11-07 |
PS
Planned sale
|
Ciaffoni Joseph
President and CEO
Executive Director
|
31,226
-15.0%
19.16
598,290
USD
|
31,226
-15.0%
|
19.16
|
598,290
USD
|
|
2019-11-08 |
2019-11-07 |
PS
Planned sale
|
Ciaffoni Joseph
President and CEO
Executive Director
|
33,595
-13.9%
18.41
618,484
USD
|
33,595
-13.9%
|
18.41
|
618,484
USD
|
|
2019-09-03 |
2019-08-29 |
S
Sale
|
Hirsch David
|
22,106
-34.4%
11.65
257,535
USD
|
22,106
-34.4%
|
11.65
|
257,535
USD
|
|
2019-07-17 |
2019-07-15 |
PS
Planned sale
|
Heffernan Michael Thomas
|
25,000
-15.9%
11.26
281,500
USD
|
25,000
-15.9%
|
11.26
|
281,500
USD
|
|
2019-07-12 |
2019-07-11 |
PS
Planned sale
|
Dreyer Scott
EVP & Chief Commercial Officer
|
2,857
-7.0%
12.31
35,170
USD
|
2,857
-7.0%
|
12.31
|
35,170
USD
|
|
2019-06-19 |
2019-06-17 |
PS
Planned sale
|
Heffernan Michael Thomas
|
2,021
-1.3%
12.05
24,353
USD
|
2,021
-1.3%
|
12.05
|
24,353
USD
|
|
2019-06-19 |
2019-06-17 |
PS
Planned sale
|
Heffernan Michael Thomas
|
22,979
-12.6%
11.31
259,892
USD
|
22,979
-12.6%
|
11.31
|
259,892
USD
|
|
2019-06-04 |
2019-06-03 |
PS
Planned sale
|
Ciaffoni Joseph
President and CEO
Executive Director
|
7,436
-4.0%
11.59
86,183
USD
|
7,436
-4.0%
|
11.59
|
86,183
USD
|
|
2019-06-04 |
2019-05-31 |
PS
Planned sale
|
Ciaffoni Joseph
President and CEO
Executive Director
|
5,851
-3.0%
11.52
67,404
USD
|
5,851
-3.0%
|
11.52
|
67,404
USD
|
|
2019-05-17 |
2019-05-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
6,517
-3.5%
13.13
85,568
USD
|
6,517
-3.5%
|
13.13
|
85,568
USD
|
|
2019-05-17 |
2019-05-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
18,483
-8.9%
12.74
235,473
USD
|
18,483
-8.9%
|
12.74
|
235,473
USD
|
|
2019-04-17 |
2019-04-15 |
PS
Planned sale
|
Heffernan Michael Thomas
|
4,808
-2.3%
15.87
76,303
USD
|
4,808
-2.3%
|
15.87
|
76,303
USD
|
|
2019-04-17 |
2019-04-15 |
PS
Planned sale
|
Heffernan Michael Thomas
|
20,192
-8.9%
14.91
301,063
USD
|
20,192
-8.9%
|
14.91
|
301,063
USD
|
|
2019-03-19 |
2019-03-15 |
PS
Planned sale
|
Heffernan Michael Thomas
|
25,000
-9.9%
17.17
429,250
USD
|
25,000
-9.9%
|
17.17
|
429,250
USD
|
|
2019-02-20 |
2019-02-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
7,068
-2.7%
15.06
106,444
USD
|
7,068
-2.7%
|
15.06
|
106,444
USD
|
|
2019-02-20 |
2019-02-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
17,932
-6.5%
14.71
263,780
USD
|
17,932
-6.5%
|
14.71
|
263,780
USD
|
|
2019-01-17 |
2019-01-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
25,000
-8.0%
15.56
389,000
USD
|
25,000
-8.0%
|
15.56
|
389,000
USD
|
|
2018-12-18 |
2018-12-17 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
3,313
-1.1%
18.57
61,522
USD
|
3,313
-1.1%
|
18.57
|
61,522
USD
|
|
2018-12-18 |
2018-12-17 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
21,687
-6.5%
18.12
392,968
USD
|
21,687
-6.5%
|
18.12
|
392,968
USD
|
|
2018-11-16 |
2018-11-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
3,600
-1.1%
17.05
61,380
USD
|
3,600
-1.1%
|
17.05
|
61,380
USD
|
|
2018-11-16 |
2018-11-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
21,400
-5.9%
16.53
353,742
USD
|
21,400
-5.9%
|
16.53
|
353,742
USD
|
|
2018-10-17 |
2018-10-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Non-Executive Director
|
25,000
-6.5%
16.53
413,250
USD
|
25,000
-6.5%
|
16.53
|
413,250
USD
|
|
2018-06-22 |
2018-06-21 |
PS
Planned sale
|
Brannelly Paul
Executive Vice President & CFO
|
4,900
-3.8%
28.35
138,915
USD
|
4,900
-3.8%
|
28.35
|
138,915
USD
|
|
2018-06-22 |
2018-06-21 |
PS
Planned sale
|
Brannelly Paul
Executive Vice President & CFO
|
5,100
-3.8%
27.50
140,250
USD
|
5,100
-3.8%
|
27.50
|
140,250
USD
|
|
2018-06-13 |
2018-06-12 |
PS
Planned sale
|
Fleming Alison B
Chief Technology Officer
|
4,096
-7.1%
27.00
110,592
USD
|
4,096
-7.1%
|
27.00
|
110,592
USD
|
|
2018-06-13 |
2018-06-12 |
S
Sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
53,057
-12.0%
25.26
1,340,220
USD
|
53,057
-12.0%
|
25.26
|
1,340,220
USD
|
|
2018-06-13 |
2018-06-11 |
S
Sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
96,943
-18.0%
25.28
2,450,719
USD
|
96,943
-18.0%
|
25.28
|
2,450,719
USD
|
|
2018-06-04 |
2018-06-01 |
PS
Planned sale
|
Ciaffoni Joseph
Chief Operating Officer
|
14,862
-14.4%
22.48
334,098
USD
|
14,862
-14.4%
|
22.48
|
334,098
USD
|
|
2018-06-04 |
2018-05-31 |
PS
Planned sale
|
Ciaffoni Joseph
Chief Operating Officer
|
5,617
-4.9%
23.35
131,157
USD
|
5,617
-4.9%
|
23.35
|
131,157
USD
|
|
2018-06-04 |
2018-05-31 |
PS
Planned sale
|
Ciaffoni Joseph
Chief Operating Officer
|
59,204
-34.0%
22.54
1,334,458
USD
|
59,204
-34.0%
|
22.54
|
1,334,458
USD
|
|
2021-03-03 |
2018-05-10 |
PS
Planned sale
|
Fleming Alison B
Chief Technical Officer
Officer
|
1,400
-0.9%
27.00
37,800
USD
|
1,400
-0.9%
|
27.00
|
37,800
USD
|
|
2018-05-14 |
2018-05-10 |
PS
Planned sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
1,500
-0.3%
27.00
40,500
USD
|
1,500
-0.3%
|
27.00
|
40,500
USD
|
|
2018-05-14 |
2018-05-10 |
PS
Planned sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
5,600
-1.0%
26.00
145,600
USD
|
5,600
-1.0%
|
26.00
|
145,600
USD
|
|
2018-04-23 |
2018-04-19 |
PS
Planned sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
100
-0.0%
26.01
2,601
USD
|
100
-0.0%
|
26.01
|
2,601
USD
|
|
2018-04-23 |
2018-04-19 |
PS
Planned sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
44,300
-7.5%
26.00
1,151,800
USD
|
44,300
-7.5%
|
26.00
|
1,151,800
USD
|
|
2018-01-23 |
2018-01-23 |
PS
Planned sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
16,408
-3.1%
25.01
410,364
USD
|
16,408
-3.1%
|
25.01
|
410,364
USD
|
|
2018-01-23 |
2018-01-22 |
PS
Planned sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
3,592
-0.7%
25.00
89,800
USD
|
3,592
-0.7%
|
25.00
|
89,800
USD
|
|
2021-03-03 |
2018-01-19 |
PS
Planned sale
|
Fleming Alison B
Chief Technical Officer
Officer
|
1,449
-0.9%
23.00
33,327
USD
|
1,449
-0.9%
|
23.00
|
33,327
USD
|
|
2021-03-03 |
2018-01-19 |
PS
Planned sale
|
Fleming Alison B
Chief Technical Officer
Officer
|
1,811
-1.1%
23.00
41,653
USD
|
1,811
-1.1%
|
23.00
|
41,653
USD
|
|
2021-03-03 |
2018-01-19 |
PS
Planned sale
|
Fleming Alison B
Chief Technical Officer
Officer
|
64
-0.0%
23.00
1,472
USD
|
64
-0.0%
|
23.00
|
1,472
USD
|
|
2021-01-11 |
2018-01-19 |
PS
Planned sale
|
Fleming Alison B
Chief Technology Officer
Officer
|
3,336
-2.9%
23.00
76,728
USD
|
3,336
-2.9%
|
23.00
|
76,728
USD
|
|
2018-01-19 |
2018-01-19 |
PS
Planned sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
20,000
-3.6%
22.50
450,000
USD
|
20,000
-3.6%
|
22.50
|
450,000
USD
|
|
2021-03-03 |
2018-01-12 |
PS
Planned sale
|
Fleming Alison B
Chief Technical Officer
Officer
|
5,753
-3.6%
21.00
120,813
USD
|
5,753
-3.6%
|
21.00
|
120,813
USD
|
|
2021-03-03 |
2018-01-12 |
PS
Planned sale
|
Fleming Alison B
Chief Technical Officer
Officer
|
1,747
-1.1%
21.00
36,687
USD
|
1,747
-1.1%
|
21.00
|
36,687
USD
|
|
2018-01-12 |
2018-01-10 |
PS
Planned sale
|
Fleming Alison B
Chief Technology Officer
Officer
|
6,928
-21.2%
19.07
132,117
USD
|
6,928
-21.2%
|
19.07
|
132,117
USD
|
|
2017-12-12 |
2017-12-08 |
S
Sale
|
Hirsch David
Major owner
|
19,650
-30.1%
17.34
340,731
USD
|
19,650
-30.1%
|
17.34
|
340,731
USD
|
|
2017-12-12 |
2017-12-08 |
S
Sale
|
Hirsch David
Major owner
|
980,350
-30.1%
17.34
16,999,269
USD
|
980,350
-30.1%
|
17.34
|
16,999,269
USD
|
|
2017-12-12 |
2017-12-08 |
S
Sale
|
Longitude Capital Partners, LLC
Major owner
|
19,650
-30.1%
17.34
340,731
USD
|
19,650
-30.1%
|
17.34
|
340,731
USD
|
|
2017-12-12 |
2017-12-08 |
S
Sale
|
Longitude Capital Partners, LLC
Major owner
|
980,350
-30.1%
17.34
16,999,269
USD
|
980,350
-30.1%
|
17.34
|
16,999,269
USD
|
|
2017-11-21 |
2017-11-21 |
PS
Planned sale
|
Fleming Alison B
Chief Technology Officer
|
572
-2.2%
19.00
10,868
USD
|
572
-2.2%
|
19.00
|
10,868
USD
|
|
2017-11-21 |
2017-11-17 |
PS
Planned sale
|
Fleming Alison B
Chief Technology Officer
|
840
-3.2%
17.00
14,280
USD
|
840
-3.2%
|
17.00
|
14,280
USD
|
|
2017-11-21 |
2017-11-17 |
PS
Planned sale
|
Fleming Alison B
Chief Technology Officer
|
1,239
-4.5%
17.00
21,063
USD
|
1,239
-4.5%
|
17.00
|
21,063
USD
|
|
2017-11-21 |
2017-11-17 |
PS
Planned sale
|
Fleming Alison B
Chief Technology Officer
|
1,950
-6.8%
17.00
33,150
USD
|
1,950
-6.8%
|
17.00
|
33,150
USD
|
|
2017-11-17 |
2017-11-15 |
PS
Planned sale
|
Heffernan Michael Thomas
Chairman, President and CEO
Executive Director
|
50,000
-8.2%
15.53
776,500
USD
|
50,000
-8.2%
|
15.53
|
776,500
USD
|
|
2017-05-15 |
2017-05-12 |
B
Purchase
|
Brannelly Paul
Executive Vice President & CFO
Officer
|
10,000
+10.0%
9.18
91,800
USD
|
10,000
+10.0%
|
9.18
|
91,800
USD
|
|
2016-08-15 |
2016-08-12 |
B
Purchase
|
Fallon John A.
Non-Executive Director
|
2,375
+inf%
10.59
25,151
USD
|
2,375
+inf%
|
10.59
|
25,151
USD
|
|
2015-05-14 |
2015-05-12 |
B
Purchase
|
Heron Patrick J
Non-Executive Director
Major owner
|
150,000
+8.6%
12.00
1,800,000
USD
|
150,000
+8.6%
|
12.00
|
1,800,000
USD
|
|
2015-05-14 |
2015-05-12 |
B
Purchase
|
TPG Group Holdings (SBS) Advisors, Inc.
|
100,000
+8.2%
12.00
1,200,000
USD
|
100,000
+8.2%
|
12.00
|
1,200,000
USD
|
|
2015-05-14 |
2015-05-12 |
B
Purchase
|
Frazier Healthcare VI, L.P.
Major owner
|
150,000
+8.6%
12.00
1,800,000
USD
|
150,000
+8.6%
|
12.00
|
1,800,000
USD
|
|
2015-05-14 |
2015-05-12 |
B
Purchase
|
Longitude Capital Partners, LLC
Major owner
|
3,930
+6.4%
12.00
47,160
USD
|
3,930
+6.4%
|
12.00
|
47,160
USD
|
|
2015-05-14 |
2015-05-12 |
B
Purchase
|
Longitude Capital Partners, LLC
Major owner
|
196,070
+6.4%
12.00
2,352,840
USD
|
196,070
+6.4%
|
12.00
|
2,352,840
USD
|
|
2015-05-13 |
2015-05-12 |
B
Purchase
|
Skyline Venture Partners V LP
Major owner
|
150,000
+5.4%
12.00
1,800,000
USD
|
150,000
+5.4%
|
12.00
|
1,800,000
USD
|
|
2015-05-13 |
2015-05-12 |
B
Purchase
|
Freund John Gordon
Non-Executive Director
Major owner
|
150,000
+5.4%
12.00
1,800,000
USD
|
150,000
+5.4%
|
12.00
|
1,800,000
USD
|
|
2015-05-13 |
2015-05-12 |
B
Purchase
|
Hirsch David
Non-Executive Director
Major owner
|
3,930
+6.4%
12.00
47,160
USD
|
3,930
+6.4%
|
12.00
|
47,160
USD
|
|
2015-05-13 |
2015-05-12 |
B
Purchase
|
Hirsch David
Non-Executive Director
Major owner
|
196,070
+6.4%
12.00
2,352,840
USD
|
196,070
+6.4%
|
12.00
|
2,352,840
USD
|
|