2019-05-24 |
2019-05-22 |
PS
Planned sale
|
HEALY JAMES
Non-Executive Director
|
257,870
-9.0%
20.69
5,335,330
USD
|
257,870
-9.0%
|
20.69
|
5,335,330
USD
|
|
2019-03-22 |
2019-03-20 |
S
Sale
|
Viret Jean-Frederic
Chief Financial Officer
|
3,000
-18.5%
14.92
44,762
USD
|
3,000
-18.5%
|
14.92
|
44,762
USD
|
|
2018-09-12 |
2018-09-10 |
PS
Planned sale
|
FINCK BARBARA K
Chief Medical Officer
Officer
|
1,760
-4.5%
18.58
32,699
USD
|
1,760
-4.5%
|
18.58
|
32,699
USD
|
|
2018-08-31 |
2018-08-29 |
PS
Planned sale
|
HEALY JAMES
Non-Executive Director
|
25,000
-0.9%
20.50
512,500
USD
|
25,000
-0.9%
|
20.50
|
512,500
USD
|
|
2018-08-15 |
2018-08-13 |
PS
Planned sale
|
FINCK BARBARA K
Chief Medical Officer
Officer
|
1,760
-4.5%
19.02
33,480
USD
|
1,760
-4.5%
|
19.02
|
33,480
USD
|
|
2018-07-25 |
2018-07-23 |
PS
Planned sale
|
Viret Jean-Frederic
Chief Financial Officer
Officer
|
9,291
-71.1%
18.56
172,472
USD
|
9,291
-71.1%
|
18.56
|
172,472
USD
|
|
2018-07-11 |
2018-07-10 |
PS
Planned sale
|
FINCK BARBARA K
Chief Medical Officer
Officer
|
1,260
-3.3%
15.00
18,900
USD
|
1,260
-3.3%
|
15.00
|
18,900
USD
|
|
2018-07-11 |
2018-07-09 |
PS
Planned sale
|
FINCK BARBARA K
Chief Medical Officer
Officer
|
500
-1.3%
15.03
7,515
USD
|
500
-1.3%
|
15.03
|
7,515
USD
|
|
2018-06-20 |
2018-06-18 |
PS
Planned sale
|
FINCK BARBARA K
Chief Medical Officer
|
1,760
-4.5%
15.00
26,400
USD
|
1,760
-4.5%
|
15.00
|
26,400
USD
|
|
2018-05-17 |
2018-05-16 |
S
Sale
|
Lanfear Dennis M
See Remarks
Executive Director
|
20,984
-1.6%
16.26
341,265
USD
|
20,984
-1.6%
|
16.26
|
341,265
USD
|
|
2017-08-10 |
2017-08-08 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
|
17,535
-26.1%
15.02
263,300
USD
|
17,535
-26.1%
|
15.02
|
263,300
USD
|
|
2017-07-07 |
2017-07-05 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
600
-0.9%
15.00
9,000
USD
|
600
-0.9%
|
15.00
|
9,000
USD
|
|
2017-06-05 |
2017-06-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
|
1,732
-2.5%
20.98
36,342
USD
|
1,732
-2.5%
|
20.98
|
36,342
USD
|
|
2017-06-05 |
2017-06-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
|
9,601
-12.1%
20.20
193,950
USD
|
9,601
-12.1%
|
20.20
|
193,950
USD
|
|
2017-05-03 |
2017-05-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
11,333
-12.5%
20.00
226,626
USD
|
11,333
-12.5%
|
20.00
|
226,626
USD
|
|
2017-04-05 |
2017-04-03 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
|
11,333
-11.1%
20.73
234,985
USD
|
11,333
-11.1%
|
20.73
|
234,985
USD
|
|
2017-03-03 |
2017-03-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
|
11,333
-10.0%
24.19
274,171
USD
|
11,333
-10.0%
|
24.19
|
274,171
USD
|
|
2017-02-03 |
2017-02-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
|
11,333
-9.1%
27.37
310,155
USD
|
11,333
-9.1%
|
27.37
|
310,155
USD
|
|
2017-01-27 |
2017-01-25 |
PS
Planned sale
|
Viret Jean-Frederic
Chief Financial Officer
|
3,900
-56.6%
27.00
105,300
USD
|
3,900
-56.6%
|
27.00
|
105,300
USD
|
|
2017-01-05 |
2017-01-03 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
|
683
-0.5%
28.60
19,536
USD
|
683
-0.5%
|
28.60
|
19,536
USD
|
|
2017-01-05 |
2017-01-03 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
|
10,650
-7.8%
27.90
297,186
USD
|
10,650
-7.8%
|
27.90
|
297,186
USD
|
|
2016-12-20 |
2016-12-16 |
PS
Planned sale
|
Viret Jean-Frederic
Chief Financial Officer
Officer
|
3,900
-62.7%
28.30
110,365
USD
|
3,900
-62.7%
|
28.30
|
110,365
USD
|
|
2016-12-09 |
2016-12-08 |
S
Sale
|
Wahlstrom Mats
Non-Executive Director
|
46,190
-100.0%
27.52
1,271,347
USD
|
46,190
-100.0%
|
27.52
|
1,271,347
USD
|
|
2016-12-09 |
2016-12-07 |
S
Sale
|
Wahlstrom Mats
Non-Executive Director
|
7,393
-13.8%
27.50
203,330
USD
|
7,393
-13.8%
|
27.50
|
203,330
USD
|
|
2016-12-05 |
2016-12-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
8,133
-5.7%
27.55
224,078
USD
|
8,133
-5.7%
|
27.55
|
224,078
USD
|
|
2016-12-05 |
2016-12-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
3,200
-2.2%
27.01
86,445
USD
|
3,200
-2.2%
|
27.01
|
86,445
USD
|
|
2016-11-22 |
2016-11-18 |
PS
Planned sale
|
Viret Jean-Frederic
Chief Financial Officer
Officer
|
3,900
-62.7%
28.19
109,955
USD
|
3,900
-62.7%
|
28.19
|
109,955
USD
|
|
2016-11-03 |
2016-11-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
11,333
-7.2%
27.53
312,042
USD
|
11,333
-7.2%
|
27.53
|
312,042
USD
|
|
2016-10-25 |
2016-10-21 |
PS
Planned sale
|
Viret Jean-Frederic
Chief Financial Officer
Officer
|
3,900
-62.7%
30.62
119,403
USD
|
3,900
-62.7%
|
30.62
|
119,403
USD
|
|
2016-10-05 |
2016-10-03 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
3,237
-2.0%
26.26
84,998
USD
|
3,237
-2.0%
|
26.26
|
84,998
USD
|
|
2016-10-05 |
2016-10-03 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
8,096
-4.8%
25.47
206,204
USD
|
8,096
-4.8%
|
25.47
|
206,204
USD
|
|
2016-09-28 |
2016-09-26 |
PS
Planned sale
|
Viret Jean-Frederic
Chief Financial Officer
Officer
|
3,900
-62.7%
29.88
116,550
USD
|
3,900
-62.7%
|
29.88
|
116,550
USD
|
|
2016-09-22 |
2016-09-21 |
PS
Planned sale
|
Lanfear Dennis M
President and CEO
Executive Director
|
50
-0.0%
31.75
1,588
USD
|
50
-0.0%
|
31.75
|
1,588
USD
|
|
2016-09-22 |
2016-09-20 |
PS
Planned sale
|
Lanfear Dennis M
President and CEO
Executive Director
|
4,010
-0.3%
31.75
127,322
USD
|
4,010
-0.3%
|
31.75
|
127,322
USD
|
|
2016-09-20 |
2016-09-16 |
PS
Planned sale
|
Lanfear Dennis M
President and CEO
Executive Director
|
2,900
-0.2%
31.79
92,199
USD
|
2,900
-0.2%
|
31.79
|
92,199
USD
|
|
2016-09-06 |
2016-09-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
16,999
-9.1%
29.99
509,715
USD
|
16,999
-9.1%
|
29.99
|
509,715
USD
|
|
2016-08-10 |
2016-08-08 |
S
Sale
|
FMR LLC
See Remark 1
|
10,000
-2.7%
29.87
298,700
USD
|
10,000
-2.7%
|
29.87
|
298,700
USD
|
|
2016-08-10 |
2016-08-08 |
S
Sale
|
FMR LLC
See Remark 1
|
84,976
-18.6%
29.86
2,537,383
USD
|
84,976
-18.6%
|
29.86
|
2,537,383
USD
|
|
2016-08-10 |
2016-08-08 |
S
Sale
|
FMR LLC
See Remark 1
|
1,349
-0.3%
29.84
40,254
USD
|
1,349
-0.3%
|
29.84
|
40,254
USD
|
|
2016-08-10 |
2016-08-08 |
S
Sale
|
FMR LLC
See Remark 1
|
1,100
-0.2%
29.92
32,912
USD
|
1,100
-0.2%
|
29.92
|
32,912
USD
|
|
2016-08-10 |
2016-08-08 |
S
Sale
|
FMR LLC
See Remark 1
|
2,100
-0.5%
29.89
62,769
USD
|
2,100
-0.5%
|
29.89
|
62,769
USD
|
|
2016-08-10 |
2016-08-08 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
15,621
-100.0%
30.00
468,649
USD
|
15,621
-100.0%
|
30.00
|
468,649
USD
|
|
2016-08-10 |
2016-08-08 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
40,000
-100.0%
30.00
1,200,016
USD
|
40,000
-100.0%
|
30.00
|
1,200,016
USD
|
|
2016-08-10 |
2016-08-08 |
S
Sale
|
FMR LLC
See Remark 1
|
475
-0.1%
29.89
14,198
USD
|
475
-0.1%
|
29.89
|
14,198
USD
|
|
2016-08-08 |
2016-08-05 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
25,000
-5.1%
28.78
719,500
USD
|
25,000
-5.1%
|
28.78
|
719,500
USD
|
|
2016-08-08 |
2016-08-04 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
100
-0.0%
27.95
2,795
USD
|
100
-0.0%
|
27.95
|
2,795
USD
|
|
2016-08-08 |
2016-08-04 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
100
-0.0%
27.87
2,787
USD
|
100
-0.0%
|
27.87
|
2,787
USD
|
|
2016-08-08 |
2016-08-04 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
200
-0.0%
27.97
5,594
USD
|
200
-0.0%
|
27.97
|
5,594
USD
|
|
2016-08-08 |
2016-08-04 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
23,200
-4.5%
28.16
653,312
USD
|
23,200
-4.5%
|
28.16
|
653,312
USD
|
|
2016-08-03 |
2016-08-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
11,333
-5.7%
25.54
289,433
USD
|
11,333
-5.7%
|
25.54
|
289,433
USD
|
|
2016-07-25 |
2016-07-21 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
700
-100.0%
26.48
18,537
USD
|
700
-100.0%
|
26.48
|
18,537
USD
|
|
2016-07-25 |
2016-07-21 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
3,291
-82.5%
26.05
85,735
USD
|
3,291
-82.5%
|
26.05
|
85,735
USD
|
|
2016-07-22 |
2016-07-20 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
23,741
-100.0%
25.00
593,525
USD
|
23,741
-100.0%
|
25.00
|
593,525
USD
|
|
2016-07-22 |
2016-07-20 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
50,000
-100.0%
25.02
1,251,210
USD
|
50,000
-100.0%
|
25.02
|
1,251,210
USD
|
|
2016-07-13 |
2016-07-11 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
43,495
-100.0%
20.02
870,931
USD
|
43,495
-100.0%
|
20.02
|
870,931
USD
|
|
2016-07-05 |
2016-07-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
4,250
-2.1%
16.89
71,775
USD
|
4,250
-2.1%
|
16.89
|
71,775
USD
|
|
2016-06-03 |
2016-06-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
4,250
-2.1%
18.67
79,360
USD
|
4,250
-2.1%
|
18.67
|
79,360
USD
|
|
2016-05-19 |
2016-05-17 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
12,000
-100.0%
20.00
240,000
USD
|
12,000
-100.0%
|
20.00
|
240,000
USD
|
|
2016-05-04 |
2016-05-02 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
552
-0.3%
19.63
10,838
USD
|
552
-0.3%
|
19.63
|
10,838
USD
|
|
2016-05-04 |
2016-05-02 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
1,493
-100.0%
20.00
29,860
USD
|
1,493
-100.0%
|
20.00
|
29,860
USD
|
|
2016-05-04 |
2016-05-02 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
3,698
-1.8%
19.13
70,753
USD
|
3,698
-1.8%
|
19.13
|
70,753
USD
|
|
2016-04-06 |
2016-04-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
977
-0.5%
21.89
21,384
USD
|
977
-0.5%
|
21.89
|
21,384
USD
|
|
2016-04-06 |
2016-04-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
3,273
-1.5%
21.20
69,379
USD
|
3,273
-1.5%
|
21.20
|
69,379
USD
|
|
2016-03-03 |
2016-03-02 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
6,015
-2.7%
15.32
92,121
USD
|
6,015
-2.7%
|
15.32
|
92,121
USD
|
|
2016-03-03 |
2016-03-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
485
-0.2%
15.00
7,276
USD
|
485
-0.2%
|
15.00
|
7,276
USD
|
|
2016-02-09 |
2016-02-05 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
2,000
-0.9%
15.02
30,040
USD
|
2,000
-0.9%
|
15.02
|
30,040
USD
|
|
2016-01-06 |
2016-01-04 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
300
-0.1%
22.36
6,707
USD
|
300
-0.1%
|
22.36
|
6,707
USD
|
|
2016-01-06 |
2016-01-04 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
3,950
-1.7%
21.40
84,545
USD
|
3,950
-1.7%
|
21.40
|
84,545
USD
|
|
2015-12-02 |
2015-12-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
8,933
-4.0%
29.67
265,072
USD
|
8,933
-4.0%
|
29.67
|
265,072
USD
|
|
2015-12-02 |
2015-12-01 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
2,400
-1.1%
28.80
69,124
USD
|
2,400
-1.1%
|
28.80
|
69,124
USD
|
|
2016-05-04 |
2015-11-20 |
PS
Planned sale
|
Watler Peter K.
Chief Technical Officer
Officer
|
20,000
-100.0%
27.41
548,178
USD
|
20,000
-100.0%
|
27.41
|
548,178
USD
|
|
2015-11-16 |
2015-11-13 |
S
Sale
|
Richards Christos
Non-Executive Director
|
4,012
-5.9%
27.93
112,051
USD
|
4,012
-5.9%
|
27.93
|
112,051
USD
|
|
2015-11-16 |
2015-11-13 |
S
Sale
|
Richards Christos
Non-Executive Director
|
7,988
-10.5%
27.38
218,681
USD
|
7,988
-10.5%
|
27.38
|
218,681
USD
|
|
2015-11-16 |
2015-11-12 |
S
Sale
|
Richards Christos
Non-Executive Director
|
3,000
-3.8%
27.23
81,693
USD
|
3,000
-3.8%
|
27.23
|
81,693
USD
|
|
2015-11-04 |
2015-11-02 |
PS
Planned sale
|
Herman Alan C.
Chief Scientific Officer
Officer
|
1,900
-0.9%
29.25
55,577
USD
|
1,900
-0.9%
|
29.25
|
55,577
USD
|
|