|
2018-12-06 |
2018-12-04 |
S
Sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,922
-2.9%
9.45
37,063
USD
|
3,922
-2.9%
|
9.45
|
37,063
USD
|
|
|
2018-12-06 |
2018-12-03 |
PS
Planned sale
|
Stonehouse Jon P
President & CEO
Executive Director
|
80,000
-9.9%
9.12
729,600
USD
|
80,000
-9.9%
|
9.12
|
729,600
USD
|
|
|
2018-12-04 |
2018-11-30 |
S
Sale
|
Barnes Alane P
Senior VP, Chief Legal Officer
Officer
|
44,290
-36.2%
9.07
401,710
USD
|
44,290
-36.2%
|
9.07
|
401,710
USD
|
|
|
2018-11-26 |
2018-11-23 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,500
-2.5%
9.66
33,810
USD
|
3,500
-2.5%
|
9.66
|
33,810
USD
|
|
|
2018-11-26 |
2018-11-21 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
7,000
-4.8%
9.08
63,560
USD
|
7,000
-4.8%
|
9.08
|
63,560
USD
|
|
|
2018-11-26 |
2018-11-21 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
5,000
-3.5%
9.41
47,050
USD
|
5,000
-3.5%
|
9.41
|
47,050
USD
|
|
|
2018-11-26 |
2018-11-21 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
2,455
-100.0%
9.01
22,120
USD
|
2,455
-100.0%
|
9.01
|
22,120
USD
|
|
|
2018-11-26 |
2018-11-21 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
12,000
-83.0%
9.06
108,720
USD
|
12,000
-83.0%
|
9.06
|
108,720
USD
|
|
|
2018-11-21 |
2018-11-20 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
6,150
-71.5%
8.61
52,952
USD
|
6,150
-71.5%
|
8.61
|
52,952
USD
|
|
|
2018-11-21 |
2018-11-20 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
9,127
-51.5%
8.52
77,762
USD
|
9,127
-51.5%
|
8.52
|
77,762
USD
|
|
|
2018-11-21 |
2018-11-20 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
6,500
-4.5%
8.75
56,875
USD
|
6,500
-4.5%
|
8.75
|
56,875
USD
|
|
|
2018-11-21 |
2018-11-20 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
4,623
-3.3%
8.57
39,619
USD
|
4,623
-3.3%
|
8.57
|
39,619
USD
|
|
|
2018-11-21 |
2018-11-19 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
193
-2.2%
8.30
1,602
USD
|
193
-2.2%
|
8.30
|
1,602
USD
|
|
|
2018-11-21 |
2018-11-19 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
75
-0.1%
8.30
623
USD
|
75
-0.1%
|
8.30
|
623
USD
|
|
|
2018-11-09 |
2018-11-08 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
5,280
-38.0%
8.15
43,032
USD
|
5,280
-38.0%
|
8.15
|
43,032
USD
|
|
|
2018-11-09 |
2018-11-08 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
2,302
-1.6%
8.30
19,107
USD
|
2,302
-1.6%
|
8.30
|
19,107
USD
|
|
|
2018-11-09 |
2018-11-08 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
11,113
-7.5%
8.09
89,904
USD
|
11,113
-7.5%
|
8.09
|
89,904
USD
|
|
|
2018-11-09 |
2018-11-07 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
300
-3.4%
8.00
2,400
USD
|
300
-3.4%
|
8.00
|
2,400
USD
|
|
|
2018-11-09 |
2018-11-07 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
672
-0.5%
8.00
5,376
USD
|
672
-0.5%
|
8.00
|
5,376
USD
|
|
|
2018-11-07 |
2018-11-05 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
215
-0.2%
8.00
1,720
USD
|
215
-0.2%
|
8.00
|
1,720
USD
|
|
|
2018-11-07 |
2018-11-05 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
100
-1.1%
8.00
800
USD
|
100
-1.1%
|
8.00
|
800
USD
|
|
|
2018-11-06 |
2018-11-02 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,500
-2.5%
7.96
27,860
USD
|
3,500
-2.5%
|
7.96
|
27,860
USD
|
|
|
2018-11-06 |
2018-11-02 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
7,356
-5.1%
7.78
57,230
USD
|
7,356
-5.1%
|
7.78
|
57,230
USD
|
|
|
2018-11-06 |
2018-11-02 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
1,000
-10.4%
8.00
8,000
USD
|
1,000
-10.4%
|
8.00
|
8,000
USD
|
|
|
2018-11-05 |
2018-11-01 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
1,544
-15.2%
7.51
11,595
USD
|
1,544
-15.2%
|
7.51
|
11,595
USD
|
|
|
2018-10-23 |
2018-10-19 |
PS
Planned sale
|
Powell Lynne
Senior VP - CCO
Officer
|
100
-1.0%
7.50
750
USD
|
100
-1.0%
|
7.50
|
750
USD
|
|
|
2018-10-23 |
2018-10-19 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,150
-2.2%
7.45
23,468
USD
|
3,150
-2.2%
|
7.45
|
23,468
USD
|
|
|
2018-10-04 |
2018-10-03 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
100
-0.1%
7.45
745
USD
|
100
-0.1%
|
7.45
|
745
USD
|
|
|
2018-10-04 |
2018-10-03 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
972
-0.7%
7.26
7,057
USD
|
972
-0.7%
|
7.26
|
7,057
USD
|
|
|
2018-10-04 |
2018-10-02 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
5,528
-3.9%
7.27
40,189
USD
|
5,528
-3.9%
|
7.27
|
40,189
USD
|
|
|
2018-10-04 |
2018-10-02 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,250
-2.3%
7.19
23,368
USD
|
3,250
-2.3%
|
7.19
|
23,368
USD
|
|
|
2018-08-13 |
2018-08-09 |
PS
Planned sale
|
Sheridan William P
Senior VP - CMO
Officer
|
62,500
-72.9%
7.03
439,375
USD
|
62,500
-72.9%
|
7.03
|
439,375
USD
|
|
|
2018-06-05 |
2018-06-01 |
PS
Planned sale
|
Sheridan William P
Senior VP - CMO
Officer
|
42,112
-66.7%
6.30
265,306
USD
|
42,112
-66.7%
|
6.30
|
265,306
USD
|
|
|
2017-11-15 |
2017-11-13 |
PS
Planned sale
|
Sheridan William P
Senior VP - CMO
|
64,310
-72.9%
4.72
303,543
USD
|
64,310
-72.9%
|
4.72
|
303,543
USD
|
|
|
2017-09-20 |
2017-09-18 |
S
Sale
|
Cohen Fred E
|
54,250
-31.2%
5.42
294,035
USD
|
54,250
-31.2%
|
5.42
|
294,035
USD
|
|
|
2017-03-22 |
2017-03-20 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,250
-2.2%
9.20
29,900
USD
|
3,250
-2.2%
|
9.20
|
29,900
USD
|
|
|
2017-03-14 |
2017-03-10 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,250
-2.7%
9.06
29,445
USD
|
3,250
-2.7%
|
9.06
|
29,445
USD
|
|
|
2017-03-10 |
2017-03-08 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,250
-2.7%
8.65
28,113
USD
|
3,250
-2.7%
|
8.65
|
28,113
USD
|
|
|
2017-03-10 |
2017-03-08 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,250
-2.6%
8.20
26,650
USD
|
3,250
-2.6%
|
8.20
|
26,650
USD
|
|
|
2017-03-08 |
2017-03-06 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,250
-2.7%
7.90
25,675
USD
|
3,250
-2.7%
|
7.90
|
25,675
USD
|
|
|
2016-12-21 |
2016-12-19 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,250
-2.6%
7.45
24,213
USD
|
3,250
-2.6%
|
7.45
|
24,213
USD
|
|
|
2016-09-16 |
2016-09-14 |
PS
Planned sale
|
Barnes Alane P
VP, General Counsel & Corp Sec
Officer
|
8,357
-9.5%
4.27
35,684
USD
|
8,357
-9.5%
|
4.27
|
35,684
USD
|
|
|
2016-08-29 |
2016-08-25 |
S
Sale
|
Babu Yarlagadda S
Senior VP - Drug Discovery
Officer
|
30,000
-21.2%
4.06
121,800
USD
|
30,000
-21.2%
|
4.06
|
121,800
USD
|
|
|
2016-08-16 |
2016-08-16 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
850
-0.0%
4.29
3,645
USD
|
850
-0.0%
|
4.29
|
3,645
USD
|
|
|
2016-08-16 |
2016-08-16 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
140
-0.0%
4.29
600
USD
|
140
-0.0%
|
4.29
|
600
USD
|
|
|
2016-08-16 |
2016-08-15 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
343,583
-3.5%
4.83
1,658,681
USD
|
343,583
-3.5%
|
4.83
|
1,658,681
USD
|
|
|
2016-08-16 |
2016-08-15 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
56,417
-3.5%
4.83
272,359
USD
|
56,417
-3.5%
|
4.83
|
272,359
USD
|
|
|
2016-08-16 |
2016-08-12 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
296,856
-3.0%
5.25
1,559,711
USD
|
296,856
-3.0%
|
5.25
|
1,559,711
USD
|
|
|
2016-08-16 |
2016-08-12 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
48,744
-2.9%
5.25
256,106
USD
|
48,744
-2.9%
|
5.25
|
256,106
USD
|
|
|
2016-08-16 |
2016-08-12 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
2,834,561
-22.0%
5.00
14,172,805
USD
|
2,834,561
-22.0%
|
5.00
|
14,172,805
USD
|
|
|
2016-08-16 |
2016-08-12 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
465,439
-21.9%
5.00
2,327,195
USD
|
465,439
-21.9%
|
5.00
|
2,327,195
USD
|
|
|
2016-08-15 |
2016-08-12 |
S
Sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
4,558
-3.5%
5.22
23,793
USD
|
4,558
-3.5%
|
5.22
|
23,793
USD
|
|
|
2016-08-15 |
2016-08-11 |
S
Sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
1,306
-1.0%
5.05
6,595
USD
|
1,306
-1.0%
|
5.05
|
6,595
USD
|
|
|
2016-08-11 |
2016-08-09 |
S
Sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
14,577
-10.1%
4.43
64,576
USD
|
14,577
-10.1%
|
4.43
|
64,576
USD
|
|
|
2016-02-09 |
2016-02-05 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
45,000
+0.4%
6.33
284,657
USD
|
45,000
+0.4%
|
6.33
|
284,657
USD
|
|
|
2016-02-04 |
2016-02-04 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
24,800
+0.2%
6.65
164,915
USD
|
24,800
+0.2%
|
6.65
|
164,915
USD
|
|
|
2016-02-04 |
2016-02-03 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
91,187
+0.7%
6.29
573,311
USD
|
91,187
+0.7%
|
6.29
|
573,311
USD
|
|
|
2016-02-04 |
2016-02-02 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
91,728
+0.7%
6.52
598,360
USD
|
91,728
+0.7%
|
6.52
|
598,360
USD
|
|
|
2016-01-29 |
2016-01-28 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
25,000
+0.2%
6.88
172,015
USD
|
25,000
+0.2%
|
6.88
|
172,015
USD
|
|
|
2016-01-29 |
2016-01-27 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
63,345
+0.5%
6.98
441,971
USD
|
63,345
+0.5%
|
6.98
|
441,971
USD
|
|
|
2016-01-25 |
2016-01-22 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
3,200
+0.0%
7.00
22,389
USD
|
3,200
+0.0%
|
7.00
|
22,389
USD
|
|
|
2016-01-25 |
2016-01-21 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
103,600
+0.8%
7.29
755,368
USD
|
103,600
+0.8%
|
7.29
|
755,368
USD
|
|
|
2016-01-20 |
2016-01-20 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
1,325
+0.0%
6.94
9,197
USD
|
1,325
+0.0%
|
6.94
|
9,197
USD
|
|
|
2016-01-20 |
2016-01-20 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
51,370
+0.4%
6.87
352,974
USD
|
51,370
+0.4%
|
6.87
|
352,974
USD
|
|
|
2016-01-20 |
2016-01-19 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
92,200
+0.7%
7.12
656,750
USD
|
92,200
+0.7%
|
7.12
|
656,750
USD
|
|
|
2016-01-20 |
2016-01-15 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
25,000
+0.2%
7.49
187,333
USD
|
25,000
+0.2%
|
7.49
|
187,333
USD
|
|
|
2016-01-20 |
2016-01-15 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
175,000
+1.4%
7.45
1,303,890
USD
|
175,000
+1.4%
|
7.45
|
1,303,890
USD
|
|
|
2015-12-22 |
2015-12-21 |
S
Sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,052
-2.2%
10.86
33,145
USD
|
3,052
-2.2%
|
10.86
|
33,145
USD
|
|
|
2015-12-18 |
2015-12-17 |
S
Sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,000
-2.1%
10.49
31,470
USD
|
3,000
-2.1%
|
10.49
|
31,470
USD
|
|
|
2015-06-24 |
2015-06-22 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,750
-2.5%
16.00
60,000
USD
|
3,750
-2.5%
|
16.00
|
60,000
USD
|
|
|
2015-06-22 |
2015-06-19 |
PS
Planned sale
|
Sheridan William P
Senior VP - CMO
Officer
|
70,389
-42.5%
15.05
1,059,354
USD
|
70,389
-42.5%
|
15.05
|
1,059,354
USD
|
|
|
2015-06-22 |
2015-06-19 |
S
Sale
|
Stonehouse Jon P
President & CEO
Executive Director
|
20,000
-3.0%
15.02
300,400
USD
|
20,000
-3.0%
|
15.02
|
300,400
USD
|
|
|
2015-06-22 |
2015-06-19 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,175
-2.1%
15.00
47,625
USD
|
3,175
-2.1%
|
15.00
|
47,625
USD
|
|
|
2015-06-22 |
2015-06-19 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,500
-2.3%
15.00
52,500
USD
|
3,500
-2.3%
|
15.00
|
52,500
USD
|
|
|
2015-06-22 |
2015-06-18 |
PS
Planned sale
|
STAAB THOMAS R II
Senior Vice President and CFO
Officer
|
3,100
-2.0%
13.50
41,850
USD
|
3,100
-2.0%
|
13.50
|
41,850
USD
|
|
