|
2021-04-14 |
2021-04-12 |
PS
Planned sale
|
Harford Simon N.R.
CFO and Treasurer
Officer
|
92
-0.7%
32.12
2,955
USD
|
92
-0.7%
|
32.12
|
2,955
USD
|
|
|
2021-04-02 |
2021-04-01 |
PS
Planned sale
|
Duncan Jason
Chief Legal Officer and GC
Officer
|
300
-3.5%
36.16
10,847
USD
|
300
-3.5%
|
36.16
|
10,847
USD
|
|
|
2021-04-02 |
2021-03-31 |
PS
Planned sale
|
Duncan Jason
Chief Legal Officer and GC
Officer
|
1,426
-14.9%
35.04
49,969
USD
|
1,426
-14.9%
|
35.04
|
49,969
USD
|
|
|
2021-03-03 |
2021-03-03 |
S
Sale
|
Mattsson Jan
Chief Scientific Officer
Officer
|
400
-1.1%
36.20
14,481
USD
|
400
-1.1%
|
36.20
|
14,481
USD
|
|
|
2021-03-03 |
2021-03-02 |
S
Sale
|
Mattsson Jan
Chief Scientific Officer
Officer
|
2,807
-6.9%
37.15
104,281
USD
|
2,807
-6.9%
|
37.15
|
104,281
USD
|
|
|
2021-03-03 |
2021-03-02 |
S
Sale
|
Mattsson Jan
Chief Scientific Officer
Officer
|
612
-1.5%
36.54
22,365
USD
|
612
-1.5%
|
36.54
|
22,365
USD
|
|
|
2021-03-03 |
2021-03-02 |
S
Sale
|
Mattsson Jan
Chief Scientific Officer
Officer
|
12,351
-23.0%
36.07
445,561
USD
|
12,351
-23.0%
|
36.07
|
445,561
USD
|
|
|
2021-03-03 |
2021-03-01 |
S
Sale
|
Mattsson Jan
Chief Scientific Officer
Officer
|
15,300
-22.2%
37.45
572,996
USD
|
15,300
-22.2%
|
37.45
|
572,996
USD
|
|
|
2021-01-25 |
2021-01-22 |
PS
Planned sale
|
Horn Patrick Taylor
Chief Medical Officer
Officer
|
110
-1.1%
34.62
3,808
USD
|
110
-1.1%
|
34.62
|
3,808
USD
|
|
|
2021-01-25 |
2021-01-22 |
PS
Planned sale
|
Duncan Jason
Chief Legal Officer and GC
Officer
|
110
-1.2%
34.62
3,808
USD
|
110
-1.2%
|
34.62
|
3,808
USD
|
|
|
2021-01-13 |
2021-01-11 |
PS
Planned sale
|
Harford Simon N.R.
CFO and Treasurer
Officer
|
110
-2.3%
37.33
4,107
USD
|
110
-2.3%
|
37.33
|
4,107
USD
|
|
|
2020-12-29 |
2020-12-28 |
PS
Planned sale
|
Stephenson Pamela
Chief Commercial Officer
Officer
|
460
-2.1%
39.07
17,974
USD
|
460
-2.1%
|
39.07
|
17,974
USD
|
|
|
2020-10-23 |
2020-10-22 |
PS
Planned sale
|
Duncan Jason
Chief Legal Officer and GC
Officer
|
89
-2.3%
34.71
3,089
USD
|
89
-2.3%
|
34.71
|
3,089
USD
|
|
|
2020-10-23 |
2020-10-22 |
PS
Planned sale
|
Horn Patrick Taylor
Chief Medical Officer
Officer
|
89
-2.0%
34.55
3,075
USD
|
89
-2.0%
|
34.55
|
3,075
USD
|
|
|
2020-10-13 |
2020-10-12 |
PS
Planned sale
|
Harford Simon N.R.
CFO and Treasurer
Officer
|
90
-1.9%
37.30
3,357
USD
|
90
-1.9%
|
37.30
|
3,357
USD
|
|
|
2020-09-25 |
2020-09-25 |
PS
Planned sale
|
Stephenson Pamela
Chief Commercial Officer
Officer
|
451
-2.0%
33.20
14,973
USD
|
451
-2.0%
|
33.20
|
14,973
USD
|
|
|
2020-09-15 |
2020-09-14 |
B
Purchase
|
PERCEPTIVE ADVISORS LLC
Major owner
|
400,000
+20.4%
40.00
16,000,000
USD
|
400,000
+20.4%
|
40.00
|
16,000,000
USD
|
|
|
2020-09-15 |
2020-09-11 |
PS
Planned sale
|
Carter Martha J.
Chief Regulatory Officer
Officer
|
10,000
-100.0%
40.03
400,300
USD
|
10,000
-100.0%
|
40.03
|
400,300
USD
|
|
|
2020-09-10 |
2020-09-10 |
PS
Planned sale
|
Carter Martha J.
Chief Regulatory Officer
Officer
|
10,000
-100.0%
42.41
424,100
USD
|
10,000
-100.0%
|
42.41
|
424,100
USD
|
|
|
2020-09-10 |
2020-09-09 |
PS
Planned sale
|
Carter Martha J.
Chief Regulatory Officer
Officer
|
2,500
-100.0%
39.82
99,550
USD
|
2,500
-100.0%
|
39.82
|
99,550
USD
|
|
|
2020-09-10 |
2020-09-09 |
PS
Planned sale
|
Carter Martha J.
Chief Regulatory Officer
Officer
|
7,500
-75.0%
38.68
290,100
USD
|
7,500
-75.0%
|
38.68
|
290,100
USD
|
|
|
2020-09-10 |
2020-09-08 |
PS
Planned sale
|
Carter Martha J.
Chief Regulatory Officer
Officer
|
10,000
-100.0%
45.55
455,500
USD
|
10,000
-100.0%
|
45.55
|
455,500
USD
|
|
|
2020-09-10 |
2020-09-08 |
PS
Planned sale
|
Duncan Jason
Chief Legal Officer and GC
Officer
|
4,000
-50.8%
45.55
182,200
USD
|
4,000
-50.8%
|
45.55
|
182,200
USD
|
|
|
2020-09-10 |
2020-09-08 |
PS
Planned sale
|
Mattsson Jan
Chief Scientific Officer
Officer
|
10,000
-29.2%
45.55
455,500
USD
|
10,000
-29.2%
|
45.55
|
455,500
USD
|
|
|
2020-07-23 |
2020-07-22 |
PS
Planned sale
|
Duncan Jason
Chief Legal Officer and GC
Officer
|
91
-2.0%
25.80
2,348
USD
|
91
-2.0%
|
25.80
|
2,348
USD
|
|
|
2020-07-23 |
2020-07-22 |
PS
Planned sale
|
Horn Patrick Taylor
Chief Medical Officer
Officer
|
91
-2.0%
25.80
2,348
USD
|
91
-2.0%
|
25.80
|
2,348
USD
|
|
|
2020-07-10 |
2020-07-10 |
PS
Planned sale
|
Harford Simon N.R.
CFO and Treasurer
Officer
|
92
-1.9%
25.56
2,352
USD
|
92
-1.9%
|
25.56
|
2,352
USD
|
|
|
2020-06-26 |
2020-06-25 |
PS
Planned sale
|
Stephenson Pamela
Chief Commercial Officer
Officer
|
397
-1.7%
30.79
12,224
USD
|
397
-1.7%
|
30.79
|
12,224
USD
|
|
|
2020-04-24 |
2020-04-22 |
PS
Planned sale
|
Duncan Jason
Chief Legal Officer and GC
Officer
|
92
-2.0%
17.68
1,627
USD
|
92
-2.0%
|
17.68
|
1,627
USD
|
|
|
2020-04-24 |
2020-04-22 |
PS
Planned sale
|
Horn Patrick Taylor
Chief Medical Officer
Officer
|
92
-2.0%
17.64
1,623
USD
|
92
-2.0%
|
17.64
|
1,623
USD
|
|
|
2020-04-13 |
2020-04-13 |
PS
Planned sale
|
Harford Simon N.R.
CFO and Treasurer
Officer
|
97
-2.0%
16.52
1,602
USD
|
97
-2.0%
|
16.52
|
1,602
USD
|
|
|
2020-03-25 |
2020-03-25 |
PS
Planned sale
|
Stephenson Pamela
Chief Commercial Officer
Officer
|
1,785
-7.1%
17.60
31,416
USD
|
1,785
-7.1%
|
17.60
|
31,416
USD
|
|
|
2020-02-04 |
2020-02-03 |
B
Purchase
|
PERCEPTIVE ADVISORS LLC
Major owner
|
255,809
+15.0%
21.00
5,371,989
USD
|
255,809
+15.0%
|
21.00
|
5,371,989
USD
|
|
|
2020-01-23 |
2020-01-22 |
PS
Planned sale
|
Horn Patrick Taylor
Chief Medical Officer
|
443
-8.9%
24.29
10,760
USD
|
443
-8.9%
|
24.29
|
10,760
USD
|
|
|
2020-01-23 |
2020-01-22 |
PS
Planned sale
|
Duncan Jason
Chief Legal Officer and GC
|
447
-8.9%
23.97
10,715
USD
|
447
-8.9%
|
23.97
|
10,715
USD
|
|
|
2020-01-14 |
2020-01-10 |
PS
Planned sale
|
Harford Simon N.R.
CFO and Treasurer
|
105
-2.1%
27.20
2,856
USD
|
105
-2.1%
|
27.20
|
2,856
USD
|
|
|
2018-11-15 |
2018-11-13 |
PP
Planned purchase
|
Cooper Ronald Harold Wilfred
President and CEO
Executive Director
|
1,026
+15.2%
25.02
25,668
USD
|
1,026
+15.2%
|
25.02
|
25,668
USD
|
|
|
2018-08-16 |
2018-08-14 |
PP
Planned purchase
|
Cooper Ronald Harold Wilfred
President and CEO
Executive Director
|
200
+3.1%
32.50
6,500
USD
|
200
+3.1%
|
32.50
|
6,500
USD
|
|
|
2018-08-16 |
2018-08-14 |
PP
Planned purchase
|
Cooper Ronald Harold Wilfred
President and CEO
Executive Director
|
588
+9.9%
31.63
18,598
USD
|
588
+9.9%
|
31.63
|
18,598
USD
|
|
|
2018-06-14 |
2018-06-13 |
PS
Planned sale
|
Mattsson Jan
Chief Operating Officer
Officer
|
6,903
-16.8%
32.08
221,448
USD
|
6,903
-16.8%
|
32.08
|
221,448
USD
|
|
|
2018-06-14 |
2018-06-12 |
PS
Planned sale
|
Mattsson Jan
Chief Operating Officer
Officer
|
2,421
-5.6%
33.23
80,450
USD
|
2,421
-5.6%
|
33.23
|
80,450
USD
|
|
|
2018-06-14 |
2018-06-12 |
PS
Planned sale
|
Mattsson Jan
Chief Operating Officer
Officer
|
15,676
-26.5%
32.19
504,610
USD
|
15,676
-26.5%
|
32.19
|
504,610
USD
|
|
|
2018-02-01 |
2018-01-30 |
S
Sale
|
Phase4 Partners Ltd
|
1,500
-0.1%
37.06
55,588
USD
|
1,500
-0.1%
|
37.06
|
55,588
USD
|
|
|
2018-02-01 |
2018-01-30 |
S
Sale
|
Phase4 Partners Ltd
|
98,500
-8.5%
34.40
3,388,459
USD
|
98,500
-8.5%
|
34.40
|
3,388,459
USD
|
|
|
2018-01-25 |
2018-01-25 |
B
Purchase
|
PERCEPTIVE ADVISORS LLC
Major owner
|
275,000
+20.8%
33.00
9,075,000
USD
|
275,000
+20.8%
|
33.00
|
9,075,000
USD
|
|
|
2017-12-05 |
2017-12-01 |
S
Sale
|
ASTRAZENECA PLC
Major owner
|
500,000
-49.6%
21.40
10,700,000
USD
|
500,000
-49.6%
|
21.40
|
10,700,000
USD
|
|
|
2014-01-02 |
2013-12-20 |
B
Purchase
|
LIEBERMAN IRA
Non-Executive Director
|
10,800
+2195.1%
2.29
24,732
USD
|
10,800
+2195.1%
|
2.29
|
24,732
USD
|
|
|
2013-12-23 |
2013-12-20 |
S
Sale
|
Pereira Brian JG
Non-Executive Director
|
4,734
-100.0%
2.26
10,699
USD
|
4,734
-100.0%
|
2.26
|
10,699
USD
|
|
|
2012-11-05 |
2012-11-02 |
PS
Planned sale
|
Krasner Alan Seth
Chief Medical Officer
Officer
|
1,100
-3.9%
2.78
3,058
USD
|
1,100
-3.9%
|
2.78
|
3,058
USD
|
|
|
2012-11-05 |
2012-11-02 |
PS
Planned sale
|
Bavier Paul S
General Counsel/Corp. Sec.
Officer
|
1,100
-3.9%
2.78
3,058
USD
|
1,100
-3.9%
|
2.78
|
3,058
USD
|
|
|
2013-09-23 |
2012-09-20 |
B
Purchase
|
DESOUZA ERROL B
CEO
|
10,000
+17.3%
3.34
33,400
USD
|
10,000
+17.3%
|
3.34
|
33,400
USD
|
|
|
2012-03-14 |
2012-03-13 |
S
Sale
|
Bavier Paul S
General Counsel/Corp. Sec.
Officer
|
8,385
-14.5%
0.59
4,947
USD
|
8,385
-14.5%
|
0.59
|
4,947
USD
|
|
|
2011-09-26 |
2011-09-26 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
43,400
-2.7%
1.05
45,570
USD
|
43,400
-2.7%
|
1.05
|
45,570
USD
|
|
|
2011-09-26 |
2011-09-23 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
34,679
-2.1%
1.09
37,800
USD
|
34,679
-2.1%
|
1.09
|
37,800
USD
|
|
|
2011-09-26 |
2011-09-22 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
52,700
-3.1%
1.12
59,024
USD
|
52,700
-3.1%
|
1.12
|
59,024
USD
|
|
|
2011-09-21 |
2011-09-21 |
PS
Planned sale
|
Steiner Solomon
Non-Executive Director
|
43,094
-2.5%
1.15
49,558
USD
|
43,094
-2.5%
|
1.15
|
49,558
USD
|
|
|
2011-09-22 |
2011-09-20 |
S
Sale
|
Krasner Alan Seth
Chief Medical Officer
Officer
|
3,855
-24.2%
1.17
4,510
USD
|
3,855
-24.2%
|
1.17
|
4,510
USD
|
|
|
2011-09-21 |
2011-09-20 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
82,723
-4.6%
1.17
96,786
USD
|
82,723
-4.6%
|
1.17
|
96,786
USD
|
|
|
2011-09-21 |
2011-09-19 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
190,700
-9.5%
1.19
226,933
USD
|
190,700
-9.5%
|
1.19
|
226,933
USD
|
|
|
2011-09-16 |
2011-09-16 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
152,020
-7.1%
1.22
185,464
USD
|
152,020
-7.1%
|
1.22
|
185,464
USD
|
|
|
2011-09-16 |
2011-09-15 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
58,157
-2.6%
1.22
70,952
USD
|
58,157
-2.6%
|
1.22
|
70,952
USD
|
|
|
2011-09-16 |
2011-09-14 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
16,400
-0.7%
1.22
20,008
USD
|
16,400
-0.7%
|
1.22
|
20,008
USD
|
|
|
2011-09-08 |
2011-09-06 |
S
Sale
|
Steiner Solomon
Major owner
|
102,699
-4.4%
1.14
117,077
USD
|
102,699
-4.4%
|
1.14
|
117,077
USD
|
|
|
2011-09-06 |
2011-09-02 |
S
Sale
|
Steiner Solomon
Major owner
|
57,319
-2.3%
1.18
67,636
USD
|
57,319
-2.3%
|
1.18
|
67,636
USD
|
|
|
2011-09-06 |
2011-09-01 |
S
Sale
|
Steiner Solomon
Major owner
|
35,477
-1.4%
1.22
43,282
USD
|
35,477
-1.4%
|
1.22
|
43,282
USD
|
|
|
2011-08-31 |
2011-08-31 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
144,755
-5.5%
1.27
183,839
USD
|
144,755
-5.5%
|
1.27
|
183,839
USD
|
|
|
2011-08-31 |
2011-08-30 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
74,279
-2.7%
1.21
89,878
USD
|
74,279
-2.7%
|
1.21
|
89,878
USD
|
|
|
2011-08-31 |
2011-08-29 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
85,471
-3.1%
1.23
105,129
USD
|
85,471
-3.1%
|
1.23
|
105,129
USD
|
|
|
2011-08-11 |
2011-08-10 |
B
Purchase
|
SANDERS CHARLES A
Non-Executive Director
|
10,000
+193.8%
1.16
11,600
USD
|
10,000
+193.8%
|
1.16
|
11,600
USD
|
|
|
2011-05-26 |
2011-05-25 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
91,859
-3.2%
2.01
184,637
USD
|
91,859
-3.2%
|
2.01
|
184,637
USD
|
|
|
2011-05-26 |
2011-05-24 |
S
Sale
|
Steiner Solomon
Non-Executive Director
|
49,739
-1.7%
2.06
102,462
USD
|
49,739
-1.7%
|
2.06
|
102,462
USD
|
|
|
2011-03-10 |
2011-03-10 |
S
Sale
|
Steiner Solomon
Non-Executive Director
Major owner
|
5,600
-0.2%
2.17
12,152
USD
|
5,600
-0.2%
|
2.17
|
12,152
USD
|
|
|
2011-03-10 |
2011-03-08 |
S
Sale
|
Steiner Solomon
Non-Executive Director
Major owner
|
164,608
-5.3%
2.23
367,076
USD
|
164,608
-5.3%
|
2.23
|
367,076
USD
|
|
|
2011-03-07 |
2011-03-04 |
S
Sale
|
Steiner Solomon
Non-Executive Director
Major owner
|
15,000
-0.5%
2.05
30,750
USD
|
15,000
-0.5%
|
2.05
|
30,750
USD
|
|
|
2011-03-07 |
2011-03-03 |
S
Sale
|
Steiner Solomon
Non-Executive Director
Major owner
|
54,124
-1.7%
2.06
111,495
USD
|
54,124
-1.7%
|
2.06
|
111,495
USD
|
|
