2022-07-27 |
2022-07-25 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
19 557
-4.5%
42,90
839 066
USD
|
19 557
-4.5%
|
42,90
|
839 066
USD
|
|
2022-07-27 |
2022-07-25 |
V
Vente
|
Urist Marshall
EVP, Research & Investments
Dirigeant
|
3 600
-15.4%
43,05
154 985
USD
|
3 600
-15.4%
|
43,05
|
154 985
USD
|
|
2022-06-29 |
2022-06-29 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
30 000
-6.6%
42,17
1 265 238
USD
|
30 000
-6.6%
|
42,17
|
1 265 238
USD
|
|
2022-06-24 |
2022-06-24 |
V
Vente
|
Urist Marshall
EVP, Research & Investments
Dirigeant
|
23 333
-50.0%
43,19
1 007 694
USD
|
23 333
-50.0%
|
43,19
|
1 007 694
USD
|
|
2022-06-10 |
2022-06-08 |
V
Vente
|
Reddoch James F.
EVP & Chief Scientific Officer
Dirigeant
|
100 000
-9.8%
41,56
4 155 900
USD
|
100 000
-9.8%
|
41,56
|
4 155 900
USD
|
|
2022-05-31 |
2022-05-27 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
13 974
-3.1%
40,77
569 754
USD
|
13 974
-3.1%
|
40,77
|
569 754
USD
|
|
2022-05-31 |
2022-05-27 |
V
Vente
|
Reddoch James F.
EVP & Chief Scientific Officer
Dirigeant
|
75 000
-6.8%
41,08
3 081 008
USD
|
75 000
-6.8%
|
41,08
|
3 081 008
USD
|
|
2022-05-31 |
2022-05-26 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
86 026
-16.2%
40,21
3 459 338
USD
|
86 026
-16.2%
|
40,21
|
3 459 338
USD
|
|
2022-05-25 |
2022-05-23 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
100 000
-15.9%
40,27
4 026 770
USD
|
100 000
-15.9%
|
40,27
|
4 026 770
USD
|
|
2022-05-23 |
2022-05-20 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
123 696
-21.5%
39,28
4 858 655
USD
|
123 696
-21.5%
|
39,28
|
4 858 655
USD
|
|
2022-05-23 |
2022-05-19 |
V
Vente
|
Reddoch James F.
EVP & Chief Scientific Officer
Dirigeant
|
75 000
-6.4%
40,44
3 033 128
USD
|
75 000
-6.4%
|
40,44
|
3 033 128
USD
|
|
2022-05-23 |
2022-05-19 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
26 304
-4.4%
40,09
1 054 651
USD
|
26 304
-4.4%
|
40,09
|
1 054 651
USD
|
|
2022-05-16 |
2022-05-16 |
V
Vente
|
Urist Marshall
EVP, Research & Investments
Dirigeant
|
23 333
-33.3%
39,85
929 836
USD
|
23 333
-33.3%
|
39,85
|
929 836
USD
|
|
2022-03-30 |
2022-03-29 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
60 000
-9.1%
38,59
2 315 322
USD
|
60 000
-9.1%
|
38,59
|
2 315 322
USD
|
|
2022-03-21 |
2022-03-21 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
14 322
-100.0%
39,05
559 288
USD
|
14 322
-100.0%
|
39,05
|
559 288
USD
|
|
2022-03-21 |
2022-03-21 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
25 545
-100.0%
39,05
997 558
USD
|
25 545
-100.0%
|
39,05
|
997 558
USD
|
|
2022-03-21 |
2022-03-18 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
56 181
-39.7%
39,77
2 234 094
USD
|
56 181
-39.7%
|
39,77
|
2 234 094
USD
|
|
2022-03-21 |
2022-03-18 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
26 238
-64.7%
39,38
1 033 334
USD
|
26 238
-64.7%
|
39,38
|
1 033 334
USD
|
|
2022-03-21 |
2022-03-18 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
46 803
-64.7%
39,38
1 843 247
USD
|
46 803
-64.7%
|
39,38
|
1 843 247
USD
|
|
2022-02-25 |
2022-02-24 |
A
Achat
|
Fernandez Henry A
Administrateur non-exécutif
|
32 500
+126.5%
37,49
1 218 373
USD
|
32 500
+126.5%
|
37,49
|
1 218 373
USD
|
|
2021-11-18 |
2021-11-17 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
31 341
-2.7%
42,33
1 326 636
USD
|
31 341
-2.7%
|
42,33
|
1 326 636
USD
|
|
2021-11-18 |
2021-11-17 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
38 815
-2.1%
42,35
1 643 749
USD
|
38 815
-2.1%
|
42,35
|
1 643 749
USD
|
|
2021-11-18 |
2021-11-17 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
69 233
-12.2%
42,35
2 931 900
USD
|
69 233
-12.2%
|
42,35
|
2 931 900
USD
|
|
2021-11-18 |
2021-11-17 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
62 435
-9.1%
42,39
2 646 401
USD
|
62 435
-9.1%
|
42,39
|
2 646 401
USD
|
|
2021-11-18 |
2021-11-17 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
84 148
-11.8%
42,39
3 566 832
USD
|
84 148
-11.8%
|
42,39
|
3 566 832
USD
|
|
2021-11-18 |
2021-11-16 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
12 565
-1.8%
42,01
527 805
USD
|
12 565
-1.8%
|
42,01
|
527 805
USD
|
|
2021-11-18 |
2021-11-16 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
65 852
-8.4%
42,12
2 773 660
USD
|
65 852
-8.4%
|
42,12
|
2 773 660
USD
|
|
2021-11-18 |
2021-11-16 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
27 341
-5.2%
43,19
1 180 822
USD
|
27 341
-5.2%
|
43,19
|
1 180 822
USD
|
|
2021-11-18 |
2021-11-16 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
72 659
-12.2%
42,33
3 075 379
USD
|
72 659
-12.2%
|
42,33
|
3 075 379
USD
|
|
2021-06-29 |
2021-06-29 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
479 800
-12.2%
41,26
19 794 437
USD
|
479 800
-12.2%
|
41,26
|
19 794 437
USD
|
|
2021-06-29 |
2021-06-29 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
1 200
-0.0%
42,01
50 409
USD
|
1 200
-0.0%
|
42,01
|
50 409
USD
|
|
2021-06-29 |
2021-06-28 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
167 448
-4.1%
42,11
7 051 269
USD
|
167 448
-4.1%
|
42,11
|
7 051 269
USD
|
|
2021-06-29 |
2021-06-25 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
487 364
-10.6%
42,69
20 807 519
USD
|
487 364
-10.6%
|
42,69
|
20 807 519
USD
|
|
2021-06-29 |
2021-06-25 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
179 100
-16.1%
42,81
7 666 501
USD
|
179 100
-16.1%
|
42,81
|
7 666 501
USD
|
|
2021-06-14 |
2021-06-10 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
10 000
-4.0%
46,45
464 491
USD
|
10 000
-4.0%
|
46,45
|
464 491
USD
|
|
2021-06-14 |
2021-06-10 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
40 000
-4.3%
46,52
1 860 772
USD
|
40 000
-4.3%
|
46,52
|
1 860 772
USD
|
|
2021-06-14 |
2021-06-10 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
20 000
-3.1%
46,46
929 106
USD
|
20 000
-3.1%
|
46,46
|
929 106
USD
|
|
2021-06-08 |
2021-06-08 |
V
Vente
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
50 000
-3.8%
46,43
2 321 540
USD
|
50 000
-3.8%
|
46,43
|
2 321 540
USD
|
|
2021-06-08 |
2021-06-07 |
V
Vente
|
Urist Marshall
EVP & Co-Head of R&I
Dirigeant
|
16 568
-100.0%
47,02
779 059
USD
|
16 568
-100.0%
|
47,02
|
779 059
USD
|
|
2021-06-08 |
2021-06-07 |
VP
Vente planifiée
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
2 210
-0.2%
47,01
103 896
USD
|
2 210
-0.2%
|
47,01
|
103 896
USD
|
|
2021-06-08 |
2021-06-07 |
VP
Vente planifiée
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
47 790
-3.5%
46,57
2 225 523
USD
|
47 790
-3.5%
|
46,57
|
2 225 523
USD
|
|
2021-06-08 |
2021-06-04 |
V
Vente
|
Urist Marshall
EVP & Co-Head of R&I
Dirigeant
|
16 566
-50.0%
45,13
747 662
USD
|
16 566
-50.0%
|
45,13
|
747 662
USD
|
|
2021-06-08 |
2021-06-04 |
V
Vente
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
100 000
-6.8%
44,60
4 459 730
USD
|
100 000
-6.8%
|
44,60
|
4 459 730
USD
|
|
2021-06-04 |
2021-06-02 |
V
Vente
|
Urist Marshall
EVP & Co-Head Research & Inv.
Dirigeant
|
14 566
-30.5%
41,52
604 850
USD
|
14 566
-30.5%
|
41,52
|
604 850
USD
|
|
2021-06-04 |
2021-06-02 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
50 000
-4.5%
42,13
2 106 385
USD
|
50 000
-4.5%
|
42,13
|
2 106 385
USD
|
|
2021-06-04 |
2021-06-02 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
12 500
-1.7%
42,09
526 128
USD
|
12 500
-1.7%
|
42,09
|
526 128
USD
|
|
2021-05-24 |
2021-05-21 |
V
Vente
|
Urist Marshall
EVP & Co-Head Research & Inv.
Dirigeant
|
100
-0.2%
41,00
4 100
USD
|
100
-0.2%
|
41,00
|
4 100
USD
|
|
2021-05-24 |
2021-05-20 |
V
Vente
|
Urist Marshall
EVP & Co-Head Research & Inv.
Dirigeant
|
1 900
-3.8%
41,08
78 059
USD
|
1 900
-3.8%
|
41,08
|
78 059
USD
|
|
2021-04-16 |
2021-04-14 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
55 898
-21.8%
42,14
2 355 486
USD
|
55 898
-21.8%
|
42,14
|
2 355 486
USD
|
|
2021-04-16 |
2021-04-14 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
13 924
-21.8%
42,12
586 434
USD
|
13 924
-21.8%
|
42,12
|
586 434
USD
|
|
2021-04-16 |
2021-04-14 |
V
Vente
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
55 714
-21.8%
42,10
2 345 593
USD
|
55 714
-21.8%
|
42,10
|
2 345 593
USD
|
|
2021-04-14 |
2021-04-12 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
360
-0.1%
42,32
15 235
USD
|
360
-0.1%
|
42,32
|
15 235
USD
|
|
2021-04-14 |
2021-04-12 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
89
-0.1%
42,32
3 766
USD
|
89
-0.1%
|
42,32
|
3 766
USD
|
|
2021-04-14 |
2021-04-12 |
V
Vente
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
359
-0.1%
42,32
15 193
USD
|
359
-0.1%
|
42,32
|
15 193
USD
|
|
2021-03-24 |
2021-03-22 |
V
Vente
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
43 927
-14.6%
46,32
2 034 519
USD
|
43 927
-14.6%
|
46,32
|
2 034 519
USD
|
|
2021-03-24 |
2021-03-22 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
100
-0.0%
47,04
4 704
USD
|
100
-0.0%
|
47,04
|
4 704
USD
|
|
2021-03-24 |
2021-03-22 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
43 642
-14.5%
46,32
2 021 436
USD
|
43 642
-14.5%
|
46,32
|
2 021 436
USD
|
|
2021-03-24 |
2021-03-22 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
10 987
-14.6%
46,34
509 086
USD
|
10 987
-14.6%
|
46,34
|
509 086
USD
|
|
2021-03-05 |
2021-03-03 |
V
Vente
|
Coyne Terrance P.
EVP & CFO
Dirigeant
|
1 456
-0.7%
46,83
68 184
USD
|
1 456
-0.7%
|
46,83
|
68 184
USD
|
|
2021-03-05 |
2021-03-03 |
V
Vente
|
Coyne Terrance P.
EVP & CFO
Dirigeant
|
11 001
-5.2%
45,86
504 459
USD
|
11 001
-5.2%
|
45,86
|
504 459
USD
|
|
2021-03-05 |
2021-03-03 |
V
Vente
|
Coyne Terrance P.
EVP & CFO
Dirigeant
|
57 723
-21.4%
45,09
2 602 465
USD
|
57 723
-21.4%
|
45,09
|
2 602 465
USD
|
|
2021-03-05 |
2021-03-03 |
V
Vente
|
Coyne Terrance P.
EVP & CFO
Dirigeant
|
29 820
-9.9%
43,71
1 303 343
USD
|
29 820
-9.9%
|
43,71
|
1 303 343
USD
|
|
2021-03-04 |
2021-03-02 |
V
Vente
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
3 510
-1.2%
47,84
167 925
USD
|
3 510
-1.2%
|
47,84
|
167 925
USD
|
|
2021-03-04 |
2021-03-02 |
V
Vente
|
Coyne Terrance P.
EVP & CFO
Dirigeant
|
5 022
-1.6%
47,88
240 429
USD
|
5 022
-1.6%
|
47,88
|
240 429
USD
|
|
2021-03-04 |
2021-03-02 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
3 510
-1.2%
47,85
167 948
USD
|
3 510
-1.2%
|
47,85
|
167 948
USD
|
|
2021-03-04 |
2021-03-02 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
96 490
-24.1%
46,89
4 524 368
USD
|
96 490
-24.1%
|
46,89
|
4 524 368
USD
|
|
2021-03-04 |
2021-03-02 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
2 625
-3.4%
47,84
125 575
USD
|
2 625
-3.4%
|
47,84
|
125 575
USD
|
|
2021-03-04 |
2021-03-02 |
V
Vente
|
Reddoch James F.
EVP, Research & Investments
Dirigeant
|
96 490
-24.1%
46,89
4 524 233
USD
|
96 490
-24.1%
|
46,89
|
4 524 233
USD
|
|
2021-03-04 |
2021-03-02 |
V
Vente
|
Coyne Terrance P.
EVP & CFO
Dirigeant
|
94 978
-23.7%
46,89
4 453 661
USD
|
94 978
-23.7%
|
46,89
|
4 453 661
USD
|
|
2021-03-04 |
2021-03-02 |
V
Vente
|
Lloyd George W.
EVP, Investments & GC
Dirigeant
|
22 375
-22.4%
46,89
1 049 258
USD
|
22 375
-22.4%
|
46,89
|
1 049 258
USD
|
|
2021-02-26 |
2021-02-25 |
A
Achat
|
Fernandez Henry A
Administrateur non-exécutif
|
25 700
+inf%
46,83
1 203 480
USD
|
25 700
+inf%
|
46,83
|
1 203 480
USD
|
|
2020-12-18 |
2020-12-18 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Actionnaire important
|
101 050
-0.3%
44,02
4 448 221
USD
|
101 050
-0.3%
|
44,02
|
4 448 221
USD
|
|
2020-12-18 |
2020-12-17 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Actionnaire important
|
7 200 000
-15.6%
43,92
316 224 000
USD
|
7 200 000
-15.6%
|
43,92
|
316 224 000
USD
|
|
2020-10-22 |
2020-10-20 |
V
Vente
|
RIGGS RORY B
Administrateur non-exécutif
|
463 200
-100.0%
42,00
19 454 400
USD
|
463 200
-100.0%
|
42,00
|
19 454 400
USD
|
|
2020-06-23 |
2020-06-18 |
A
Achat
|
Coyne Terrance P.
EVP & CFO
Dirigeant
|
1 450
+inf%
28,00
40 600
USD
|
1 450
+inf%
|
28,00
|
40 600
USD
|
|